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Diclofenac + Omeprazole

Uses of Diclofenac + Omeprazole

  • Diclofenac + Omeprazole is primarily used to manage pain and inflammation. It belongs to the group of NSAIDs and proton pump inhibitors (PPIs).

  • Secondary uses of this combination include managing conditions like rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute musculoskeletal pain, postoperative pain, and migraines. The omeprazole component helps to prevent NSAID-related ulcers and gastric mucosal damage.

Side effects of Diclofenac + Omeprazole

  • Nausea

  • Vomiting

  • Abdominal pain

  • Diarrhoea or constipation

  • Dizziness

How Diclofenac + Omeprazole works

  • Diclofenac + Omeprazole is an anti-inflammatory and acid-reducing combination.

  • Diclofenac is a non-steroidal anti-inflammatory medicine. It reduces pain, fever, and inflammation by blocking chemicals called cyclooxygenase (COX) enzymes. These enzymes help to produce prostaglandins, substances in the body that cause pain and inflammation. By blocking these enzymes, diclofenac decreases the levels of prostaglandins and reduces inflammation and pain.

  • Omeprazole is a proton pump inhibitor. It works by blocking a system in the stomach known as the proton pump. This pump is responsible for producing stomach acid. By blocking this system, omeprazole reduces the amount of acid produced in the stomach. This helps to prevent damage to the stomach lining and ulcers that can occur after prolonged use of non-steroidal anti-inflammatory medicines like diclofenac.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Diclofenac + Omeprazole is available as modified-release capsules and tablets.

  • This medication is to be taken orally.

Age and Dose Restrictions

  • This combination is meant for adults only.

Contraindications

  • This combination is contraindicated in patients with hypersensitivity to NSAIDs or omeprazole. It is also contraindicated in individuals with active gastrointestinal bleeding or ulceration, severe heart failure, and severe hepatic or renal impairment. Additionally, patients who have experienced asthma, urticaria, or anaphylactic reactions induced by NSAIDs should avoid this medicine.

Other Medications to Avoid

  • Diclofenac + Omeprazole may interact with other nonsteroidal anti-inflammatory agents (NSAIDs) (like ibuprofen), anticoagulants (such as warfarin), and certain antifungals (like ketoconazole). These interactions can affect the effectiveness and safety of the treatment.

Overdose and Missed Dose

  • An overdose of Diclofenac + Omeprazole could potentially lead to an increased risk of gastrointestinal bleeding, kidney damage, or other severe adverse effects. Immediate medical attention is necessary in the event of an overdose.

  • If you miss a dose of this medication, take it as soon as you remember unless it is nearly time for your next dose. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Taking the medication with food can help reduce gastrointestinal discomfort such as nausea or stomach pain.

  • Drinking adequate water may help alleviate symptoms like dry mouth or constipation linked to medication usage.

Use in Driving and Operating Machinery

  • This medication may impair your ability to drive or operate heavy machinery, particularly if you experience side effects such as dizziness or drowsiness.

Use in Pregnancy and Lactation

  • Diclofenac + Omeprazole is not recommended during the third trimester of pregnancy due to risks of fetal harm.

  • It is advised to consult your doctor regarding its use during pregnancy and while breastfeeding.

Caution in Other Conditions

  • Patients with a history of ulcers or gastrointestinal bleeding should use Diclofenac + Omeprazole with caution.

  • Extreme caution is advised for patients with renal or hepatic impairment.

Special Dietary and Lifestyle Recommendations

  • Maintaining hydration by drinking plenty of fluids can help manage risks associated with renal function.

  • A balanced diet rich in fruits, vegetables, and fibre can help maintain digestive health and prevent complications such as constipation or bloating often seen with NSAID use.

  • Limiting the intake of substances that can increase stomach acidity, such as coffee, spicy foods, and alcohol, may be beneficial for those at risk of gastrointestinal side effects.

  • Regular monitoring by a doctor is recommended to adjust the diet or lifestyle as necessary based on individual health needs and medication effects.

Frequently asked questions

No, Diclofenac + Omeprazole is not a steroid. This combination belongs to the class of medications known as NSAIDs and proton pump inhibitors (PPIs).

Diclofenac + Omeprazole is not commonly known to directly affect sleep. However, Diclofenac may cause side effects like indigestion or stomach discomfort, which could indirectly disrupt sleep. If sleep disturbances occur, consult your doctor.

There is no direct evidence suggesting that Diclofenac + Omeprazole affects fertility. However, if you have concerns about fertility, it is best to consult your doctor before starting any new medication.

There are no specific dietary restrictions when taking Diclofenac + Omeprazole, but it is generally recommended to take the medication with food to minimise possible gastrointestinal side effects.

The safety of taking Diclofenac + Omeprazole daily depends on the patient's individual health condition and their doctor's advice. It is important not to exceed the prescribed dose and duration.

The time required for Diclofenac + Omeprazole to work can vary depending on the severity of the condition being managed. Your doctor would be able to give you a more accurate timeline.

The best time to take this medication will be determined by your doctor.

Terms & Conditions


Diclofenac + Omeprazole in other salts

DICLOFENACDICLOFENAC DIETHYLAMINE + LINSEED OIL + MENTHOL + METHYL SALICYLATEDICLOFENAC + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + OMEPRAZOLEESOMEPRAZOLEESOMEPRAZOLE + LEVOSULPIRIDEOMEPRAZOLEDOMPERIDONE + ESOMEPRAZOLECHLORZOXAZONE + DICLOFENAC + PARACETAMOLDICLOFENAC + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL + SERRATIOPEPTIDASETRYPSIN + BROMELAIN + RUTOSIDE + DICLOFENACDICLOFENAC + RABEPRAZOLEDICLOFENAC + NIMESULIDEDICLOFENAC + EPERISONEESOMEPRAZOLE + ITOPRIDEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEAMOXICILLIN + OMEPRAZOLE + TINIDAZOLEAMOXICILLIN + CLARITHROMYCIN + ESOMEPRAZOLEDICLOFENAC + LINSEED OIL + MENTHOL + METHYL SALICYLATEDICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATEDICLOFENAC SODIUMCAPSAICIN + DICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATEDICLOFENAC DIETHYLAMINE + LINSEED OIL + MENTHOL + METHYL SALICYLATE + THIOCOLCHICOSIDEDICLOFENAC SODIUM + MENTHOL + METHYL SALICYLATECAPSAICIN + DICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATE + PREGABALINDICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATE + VIRGIN LINSEED OILBROMELAIN + DICLOFENAC + RUTOSIDE + TRYPSIN-CHYMOTRYPSINDICLOFENAC + METHOCARBAMOL + PARACETAMOL/ACETAMINOPHENDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINDICLOFENAC + TRYPSIN-CHYMOTRYPSINDICLOFENAC + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + TRAMADOLDICLOFENAC + FAMOTIDINEDICLOFENAC + TIZANIDINEESOMEPRAZOLE + NAPROXENDICLOFENAC + METAXALONEDICLOFENAC + TOLPERISONEDICYCLOMINE + OMEPRAZOLE
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