Naprosyn D 500 Mg Tablet 10

Naprosyn D 500 Tablet 10

Rpg Life Sciences Ltd.

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Composition

Domperidone (10 Mg) + Naproxen (500 Mg)

Naprosyn D 500 Tablet is primarily used for the prevention of migraines, offering relief from pain, inflammation and associated symptoms like nausea and vomiting. This combination medicine falls under the group of nonsteroidal anti-inflammatory drugs (NSAIDs) and prokinetic agents.

In addition to its primary use, these tablets also help manage various conditions that cause pain, tenderness, swelling and stiffness. These may include osteoarthritis, rheumatoid arthritis, juvenile arthritis, ankylosing spondylitis, tendinitis, bursitis, gout and menstrual pain.

As directed by your doctor, this medicine should be taken orally. Before starting this medicine, it's important to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. For the best results, continue taking the medicine for the duration prescribed by your doctor.

Naprosyn D 500 Tablet is used for the following:

Prevention of migraines
Relief from osteoarthritis symptoms
Management of rheumatoid arthritis
Managing juvenile arthritis
Reduction of ankylosing spondylitis symptoms
Handling tendinitis and bursitis
Gout treatment.
Dealing with menstrual pain
Management of mild to moderate pain

Directions for Use of Naprosyn D 500 Tablet 10

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet, as this could affect how it works.
Always take your medicine at consistent times each day for best results.
Never exceed the dose prescribed by your doctor.

Naprosyn D 500 Tablet is taken orally.

Side Effects of Naprosyn D 500 Tablet 10

Naprosyn D 500 Tablet may cause the following side effects:

Nausea
Vomiting
Diarrhoea
Constipation
Abdominal pain
Indigestion
Photosensitivity: This means your skin may react faster than usual to sunlight, causing sunburn.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Naprosyn D 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Indigestion: Try taking Naprosyn D 500 Tablet after meals to lessen this effect.
Photosensitivity: If you notice your skin reacting to sunlight after taking this medicine, consider limiting your exposure to sunlight and applying sunscreen when going outside.

Naprosyn D 500 Tablet contains two active ingredients which act on your body in the following way:

Domperidone (10 mg): This is an antiemetic and prokinetic agent that works by blocking dopamine receptors in your gut. It increases the movement of food through your digestive system and reduces feelings of nausea. Domperidone also inhibits signals in your brain that trigger nausea and vomiting linked with migraines.
Naproxen (500 mg): As a nonsteroidal anti-inflammatory drug (NSAID), naproxen functions by inhibiting the release of specific chemical messengers responsible for pain and inflammation. It blocks the production of prostaglandins which play a crucial role in pain and inflammation pathways.

Pregnancy

Consult your doctor before taking this medicine as it is contraindicated for use when pregnant.

Breastfeeding

Caution is advised when using Naprosyn D 500 Tablet for breastfeeding women. Please discuss this with your doctor before starting the medicine.

Alcohol

Mixing alcohol and Naprosyn D 500 Tablet may increase the risk of side effects. It's best to avoid alcohol while taking this medicine.

Liver

Caution is advised while taking Naprosyn D 500 Tablet in case of mild to moderate liver impairment. This medicine may affect liver function, so it's crucial to discuss any liver problems with your doctor before starting this medication.

Kidney

If you have a history of kidney problems, be careful before taking Naprosyn D 500 Tablet. Always consult your doctor beforehand.

Using Machines & Driving

Naprosyn D 500 Tablet may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Ensure you know how this medicine affects you before engaging in these activities.

Allergy

If you're allergic to domperidone or naproxen, or any other component of Naprosyn D 500 Tablet, avoid taking it. Always inform your doctor about all known allergies before starting a new medication.

Children

Children under 18 years of age should be given Naprosyn D 500 Tablet with caution. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Naprosyn D 500 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Naprosyn D 500 Tablet 10

Drug-Drug Interactions

Naprosyn D 500 Tablet interacts with the following medicines:

Anticoagulants and antiplatelet medicines such as warfarin, aspirin, and clopidogrel may interact with Naprosyn D 500 Tablet, potentially increasing the risk of bleeding.
Diuretics like furosemide and hydrochlorothiazide may experience decreased effectiveness when taken alongside Naprosyn D 500 Tablet.
Selective Serotonin Reuptake Inhibitors (SSRIs) like citalopram or fluoxetine may interact with this medicine, potentially increasing the risk of gastrointestinal bleeding.

Drug-Food Interactions

Certain foods can affect the absorption of Naprosyn D 500 Tablet. For instance:

Grapefruit: This fruit can interfere with how the medicine works, potentially leading to increased side effects.

Drug-Disease Interactions

Naprosyn D 500 Tablet interacts with the following diseases:

Gastrointestinal disorders: The use of Naprosyn D 500 Tablet could exacerbate conditions such as peptic ulcers or active gastrointestinal bleeding.
Cardiovascular disease: People with heart conditions should exercise caution as this medication could potentially increase blood pressure or cause fluid retention.
Kidney Impairment: This medication can worsen renal function in individuals already suffering from kidney disease.
Liver dysfunction: Those with liver disease should exercise caution as this medicine could exacerbate their condition.

Daily Dose

The daily dose of Naprosyn D 500 Tablet should be followed as recommended by your doctor. Factors like how severe your condition is and how well you respond to the medicine might affect your dosage. You must stick to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Overdosing on Naprosyn D 500 Tablet could cause overdose side effects like feeling sick, vomiting, and diarrhoea. If you think you've taken too much of this medicine, let your doctor know right away.

Missed Dose

In case you forget to take Naprosyn D 500 Tablet at the usual time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't increase your dose without discussing it with your doctor.

Store your Naprosyn D 500 Tablet in a cool, dry place away from direct sunlight and moisture.
Ensure the medicine packaging is properly sealed to prevent air exposure.
Strictly keep this medicine out of reach of children for their safety.
Always check the expiry date and avoid using the product post expiry.

Foods rich in omega-3s like flaxseeds, walnuts, and fatty fish may help reduce inflammation.
Regular gentle exercises such as swimming or walking can be beneficial if you're managing conditions causing stiffness and pain. Remember to consult your doctor before starting any exercise regimen.

Fact Box

Drug Category	Antiemetic, NSAID
Therapeutic Category	Pain management
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Migraines, osteoarthritis, menstrual pain

What does Naprosyn D 500 Tablet do?

Naprosyn D 500 Tablet helps manage migraines, reduces pain and inflammation, and minimises symptoms like nausea and vomiting.

How does Naprosyn D 500 Tablet work?

This medicine contains two active ingredients, domperidone and naproxen that reduce pain and inflammation, improve food movement in the gut, and decrease nausea.

Can I take Naprosyn D 500 Tablet without food?

While it can be taken with or without food, consuming it with a meal may lessen the risk of stomach-related side effects.

How soon will I notice the effects of Naprosyn D 500 Tablet?

Pain relief might be noticed within one to two hours, while anti-inflammatory effects could take several days to weeks.

What should I do if I miss a dose of Naprosyn D 500 Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.

Can I use Naprosyn D 500 Tablet for long-term treatment?

Long-term use should be under a doctor's supervision due to potential side effects. Regular health check-ups are recommended.

What are the potential side effects of Naprosyn D 500 Tablet?

Common side effects include nausea, vomiting, diarrhoea, constipation, headache, dizziness, drowsiness, rash and swelling in extremities. Consult your doctor if these persist.

Last Updated On 03 May. 2024 | 4:16PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

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References

P. (n.d.). Domperidone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone
Brutzkus, J. C., Shahrokhi, M., & Varacallo, M. (2023, August 4). Naproxen. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK525965/
Naproxen: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a681029.html
Website, N. (2023, March 15). Naproxen. nhs.uk. https://www.nhs.uk/medicines/naproxen/
Website, N. (2024, March 21). Domperidone. nhs.uk. https://www.nhs.uk/medicines/domperidone/
Domperidone: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01184
Naproxen (Aleve®). (2022, May 1). Mother to Baby | Fact Sheets - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK582870/
Dart R. C. (2001). The use and effect of analgesics in patients who regularly drink alcohol. The American journal of managed care, 7(19 Suppl), S597–S601.

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