Lopmide Capsule 10

Universal Lifesciences

Pack of 10 Units

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MRP ~~₹42.33~~

₹21.12

₹4.23/Units

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Composition

Loperamide (2 Mg)

Lopmide Capsule 10 is primarily used to manage acute episodes of diarrhoea. Although it belongs to the opioid class of medications, it works solely within the gut and does not produce the same effects as other opioids.

In addition to treating acute diarrhoea, it also provides relief from chronic diarrhoea associated with inflammatory bowel diseases like Crohn's disease and ulcerative colitis. It can also help reduce the volume of faecal matter in patients who have undergone ileostomies.

Before starting this medication, consult your doctor for guidance on dosage and frequency. Inform your doctor about any pre-existing conditions or ongoing medications before taking this capsule. If you experience any side effects, notify your doctor immediately. It's essential to take the medicine as prescribed for its full duration to achieve the best results.

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Lopmide Capsule 10 is used in the following conditions:

Managing sudden, acute episodes of diarrhoea
Providing relief from traveller's diarrhoea
Controlling chronic diarrhoea associated with inflammatory bowel diseases (IBS) like Crohn's disease and ulcerative colitis
Reducing faecal volume in patients who have undergone ileostomy
Assisting in the management of diarrhoea due to viral or bacterial infections and food poisoning
Helping manage diarrhoea episodes during IBS flare-ups

Directions for Use of Lopmide Capsule 10

Before taking Lopmide Capsule 10, keep these simple steps in mind:

Swallow the capsule whole with a full glass of water.
Do not chew or crush it.
If you experience constipation or if there's no improvement in your symptoms after 48 hours, stop using this medicine and consult your doctor.

Lopmide Capsule 10 is taken orally.

Lopmide Capsule 10 may have the following common side effects:

Constipation
Dizziness
Abdominal pain
Nausea
Dry mouth
Difficult urination
Irregular heartbeat

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Lopmide Capsule 10. However, if you experience serious side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Constipation: Try taking Lopmide Capsule 10 with plenty of water and fibre-rich food.
Dizziness: Consider taking this medicine at night if it makes you feel dizzy or sleepy during the day.

Lopmide Capsule 10 contain loperamide (2 mg), which interacts with your body in several ways:

Acetylcholine and prostaglandin inhibition: Loperamide reduces peristaltic contractions within your intestines by inhibiting the release of acetylcholine and prostaglandins.
Slowing gut motility: The active ingredient increases intestinal transit time by slowing down the movement of fluids through the intestines.
Fluids and electrolyte absorption: It promotes the absorption of fluids and electrolytes from the intestinal lumen, reducing fluid loss during episodes of diarrhoea.
Anal sphincter tone increase: The resting anal sphincter tone is increased due to loperamide's action, contributing to a reduction in stool frequency.

Pregnancy

Caution is advised while taking Lopmide Capsule 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's essential to discuss with your doctor before using Lopmide Capsule 10.

Alcohol

There's no specific information about the interaction of Lopmide Capsule 10 with alcohol. However, it's always wise to consult your doctor regarding this matter.

Liver

People with liver disease should use Lopmide Capsule 10 cautiously, as it is processed by the liver. If you have any liver problems, discuss them with your doctor before starting this medication.

Kidney

There's limited information about the effects of Lopmide Capsule 10 on kidney health. So, if you have any kidney health issues, make sure to consult your doctor before taking this medicine.

Using Machines & Driving

Lopmide Capsule 10 may cause dizziness and drowsiness. Exercise caution while driving or operating machinery after taking this medicine.

Allergy

Lopmide Capsule 10 is contraindicated for those who are hypersensitive to loperamide or any other inactive ingredients in the medicine. If you've had allergic reactions to medicines in the past, talk to your doctor first.

Children

Lopmide Capsule 10 is not recommended for children under 2 years of age. Always consult your doctor before giving it to children in this age group.

Older Patients

Older patients should take Lopmide Capsule 10 under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Lopmide Capsule 10 interacts with the following medicines:

Cholesterol-lowering medicines: Gemfibrozil and rosuvastatin can increase loperamide levels in your blood, potentially enhancing both its effects and side effects.
Antifungal medication: Itraconazole and ketoconazole can raise loperamide levels, possibly leading to increased effects or side effects.
Heart medications: Quinidine and procainamide can elevate loperamide levels, potentially causing side effects.
Antiviral medications: Ritonavir and dolutegravir can increase loperamide levels, possibly enhancing effects or side effects.
Diuretics: Desmopressin and indapamide may increase the risk of water intoxication when taken with Lopmide Capsule 10.
Antibiotics: Amoxicillin, ampicillin, cefixime, and clindamycin can cause antibiotic-associated diarrhoea when used with Lopmide Capsule 10.

Drug-Food Interactions

There are no known food interactions with Lopmide Capsule 10.

Drug-Disease Interactions

Lopmide Capsule 10 interacts with the following diseases:

Liver disease: If you have liver disease, use Lopmide Capsule 10 with caution as it's extensively metabolised by the liver. Your doctor may need to adjust your dosage.
Intestinal disorders: Lopmide Capsule 10 should be avoided if you have abdominal pain without diarrhoea or constipation. It's also contraindicated in certain intestinal conditions, like acute ulcerative colitis and bacterial enterocolitis caused by Salmonella, Shigella, or Campylobacter.

Daily Dose

The daily dose of Lopmide Capsule 10 should be taken as instructed by your doctor. This may vary based on individual factors, such as the severity of your condition and your response to treatment. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

Overdosing on Lopmide Capsule 10 may lead to common side effects such as constipation, dizziness, abdominal pain, or dry mouth. If you experience these symptoms persistently after taking more than the prescribed dose, inform your doctor.

Missed Dose

If you forget to take a scheduled dose of Lopmide Capsule 10, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.

Ensure to store Lopmide Capsule 10 in a cool, dry place where the temperature stays below 30°C.
Avoid exposure to light and moisture.
Always keep this medicine out of reach of children.

If you're taking Lopmide Capsule 10 to manage sudden bouts of diarrhoea, remember to drink plenty of fluids. This helps replace the fluid lost from your body due to diarrhoea.
A low-fibre diet can benefit those managing chronic diarrhoea caused by conditions such as Crohn's disease. It reduces the amount of undigested food and, therefore, lessens stool weight and frequency. Please consult your doctor for a personalised diet plan based on your health condition.

Fact Box

Drug Category	Opioid Receptor Agonist
Therapeutic Category	Antidiarrhoeal
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Acute Diarrhoea, Chronic Diarrhoea

What is the main use of Lopmide Capsule 10?

Lopmide Capsule 10 is mainly used to manage sudden episodes of diarrhoea, including traveller's diarrhoea.

How does Lopmide Capsule 10 work?

Lopmide Capsule 10 slows down intestine activity, reducing the frequency and volume of stools, thereby managing diarrhoea symptoms.

Can I drink alcohol while taking Lopmide Capsule 10?

It's best to avoid alcohol when taking Lopmide Capsule 10 as it can exacerbate diarrhoea and complicate the condition.

Is Lopmide Capsule 10 safe for everyone to take?

No, people with certain conditions, like ulcerative colitis or bloody stools, should not take this medicine. Always consult your doctor first.

Can I drive after taking Lopmide Capsule 10?

Caution is advised as Lopmide Capsule 10 may cause dizziness or drowsiness, which could affect your ability to drive or operate machinery.

What should I do if I experience side effects from taking Lopmide Capsule 10?

If you experience severe side effects like blood in stools or irregular heartbeat, seek immediate medical attention.

How should I store my Lopmide Capsule 10?

Store them at a temperature below 30°C, away from light and moisture, and out of reach of children.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

References

FDA warns about serious heart problems. (2018, January 29). U.S. Food and Drug Administration. https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-warns-about-serious-heart-problems-high-doses-antidiarrheal
Sahi N, Nguyen R, Patel P, et al. Loperamide. (2024, February 28). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK557885/
Loperamide: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682280.html
Loperamide: A medicine used to treat diarrhoea. (2024, April 11). NHS. https://www.nhs.uk/medicines/loperamide/
Loperamide. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00836

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