Ibiflo S 50500 Mg Nexcap 30

Ibiflo S 50/500 MG Nexcap 30

Indiabulls Pharmaceuticals Ltd

Bottle of 30 Units

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Composition

Fluticasone Propionate (500 Mcg) + Salmeterol (50 Mcg)

Ibiflo S 50/500 MG Nexcap 30 is primarily utilised to manage chronic obstructive pulmonary disease (COPD) and asthma in adults. This medication is a combination of two active ingredients and is classified as a corticosteroid and a long-acting beta-2 agonist.

In addition to its primary use, this medicine is indicated for the maintenance treatment of airflow obstruction and for the prevention of exacerbations in patients with COPD, which includes chronic bronchitis and emphysema. It is also employed in the long-term, twice-daily maintenance treatment of asthma in patients aged four and above.

This medicine should be taken orally as directed by your doctor. Ensure you inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. Continue taking the medicine for the period prescribed by your doctor for optimal results.

Ibiflo S 50/500 MG Nexcap 30 is used for the following:

Maintenance and management of airflow obstruction in adult patients
Prevention of worsening or flare-ups in chronic obstructive pulmonary disease (COPD) patients
Long-term control of asthma symptoms in individuals aged 4 years and older
Management of chronic bronchitis in adults
Control of emphysema symptoms in adults

Directions for Use of Ibiflo S 50/500 MG Nexcap 30

To effectively use Ibiflo S 50/500 MG Nexcap 30, please follow these instructions:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Ibiflo S 50/500 MG Nexcap 30 should be inhaled with a dry powder Rotanex.

The common side effects of Ibiflo S 50/500 MG Nexcap 30 may include:

Nasopharyngitis: This refers to inflammation of the nasal passages and the upper part of your throat.
Pharyngitis: This is a type of sore throat caused by inflammation of the back of the throat.
Upper respiratory tract infections
Oral candidiasis: This is a yeast infection in your mouth, commonly referred to as thrush.
Headache
Hoarseness and throat irritation
Cough
Musculoskeletal pain: This refers to pain in your muscles, ligaments, tendons, and bones.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Ibiflo S 50/500 MG Nexcap 30. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are two general guidelines for managing common side effects:

Oral candidiasis: Maintain good oral hygiene and rinse your mouth after each dose to minimise this effect.
Musculoskeletal pain: If you experience this after using Ibiflo S 50/500 MG Nexcap 30, consider taking your dose at bedtime.

Ibiflo S 50/500 MG Nexcap 30 contains two active ingredients:

Fluticasone propionate (500 mcg): This synthetic trifluorinated corticosteroid has potent anti-inflammatory activity. It works by binding to the glucocorticoid receptors in the cells of your airways and suppressing the release of inflammatory mediators such as leukotrienes and cytokines. This action reduces inflammation, swelling, and mucus production in the airways.
Salmeterol (50 mcg): Salmeterol is a selective, long-acting beta-2 adrenergic agonist. It stimulates the beta-2 receptors in the smooth muscles of your airways. This activity leads to the relaxation of the bronchial smooth muscles and dilation of the airways, relieving bronchospasms and improving airflow for up to 12 hours.

The combined actions of these two components help improve lung function, reduce symptoms, and prevent COPD and asthma exacerbations when used regularly as prescribed.

Pregnancy

Caution is advised while taking Ibiflo S 50/500 MG Nexcap 30 if you are pregnant. It is best to consult your doctor before starting this medicine.

Breastfeeding

If you're breastfeeding, it's recommended to talk to your doctor before starting on Ibiflo S 50/500 MG Nexcap 30, as it's unclear whether the medicine passes into breast milk.

Alcohol

There's no known interaction between Ibiflo S 50/500 MG Nexcap 30 and alcohol. However, it's always a good idea to discuss your drinking habits with your doctor.

Liver

Ibiflo S 50/500 MG Nexcap 30 should be used with caution by patients with liver problems. If you have any liver health issues, discuss them with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, use Ibiflo S 50/500 MG Nexcap 30 with caution. Make sure to consult your doctor before taking this medicine.

Using Machines & Driving

Ibiflo S 50/500 MG Nexcap 30 doesn't generally affect your ability to drive or operate machinery. However, if you feel unwell or dizzy after using the medicine, avoid these activities until you feel better.

Allergy

Avoid using Ibiflo S 50/500 MG Nexcap 30 if you have severe hypersensitivity to milk proteins or any ingredients in the formulation. Always check the ingredient list and discuss any allergies with your doctor.

Children

Children under 4 years of age should not use Ibiflo S 50/500 MG Nexcap 30. For children aged 4 and above, consult your doctor before giving this medicine.

Older Patients

Older patients can use Ibiflo S 50/500 MG Nexcap 30 under medical supervision as they may experience more side effects. It's especially important to discuss any existing liver or kidney issues with your doctor before starting this medication.

Interactions of Ibiflo S 50/500 MG Nexcap 30

Drug-Drug Interactions

Ibiflo S 50/500 MG Nexcap 30 interacts with the following medicines:

Antifungals: Medicines like ketoconazole may interact with Ibiflo S 50/500 MG Nexcap 30, possibly increasing the risk of side effects due to higher levels of fluticasone and salmeterol in your body.
Monoamine oxidase inhibitors (MAOIs): Medicines like phenelzine or tranylcypromine, when taken with Ibiflo S 50/500 MG Nexcap 30, can increase the risk of high blood pressure or other cardiovascular effects.
Tricyclic antidepressants: Antidepressants such as amitriptyline or nortriptyline can enhance the effect of salmeterol, potentially leading to an increased heart rate or blood pressure.
Other adrenergic medicines: Medications like epinephrine or pseudoephedrine, which stimulate your nervous system, may increase the bronchodilatory effects of salmeterol, potentially leading to excessive heart stimulation.
Xanthine derivatives: Medicines such as theophylline, when used with Ibiflo S 50/500 MG Nexcap 30, can lead to a higher risk of cardiac-related side effects.

Drug-Food Interactions

There are no specific food items known to interact with Ibiflo S 50/500 MG Nexcap 30.

Drug-Disease Interactions

Ibiflo S 50/500 MG Nexcap 30 interacts with the following diseases:

Cardiovascular disorders: If you have coronary insufficiency, arrhythmias, or hypertension, use Ibiflo S 50/500 MG Nexcap 30 cautiously as it could worsen these conditions.
Convulsive disorders or thyrotoxicosis: Use this medicine carefully as it may exacerbate these conditions.
Diabetes mellitus: This medicine might impact blood sugar control, so close monitoring is necessary if you're diabetic.
Hepatic impairment: Hepatic disease could affect how your body processes this medicine, altering its effectiveness or potentially increasing the risk of side effects.
Tuberculosis, untreated fungal/bacterial/viral infections, or ocular herpes simplex: If you have any of these conditions, Ibiflo S 50/500 MG Nexcap 30 may worsen them or cause complications.

Daily Dose

The daily dose of Ibiflo S 50/500 MG Nexcap 30 should be as advised by your doctor. This dosage can vary depending on individual factors like the severity of your condition or how you respond to the medicine. Always follow your doctor's prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Overdosing on Ibiflo S 50/500 MG Nexcap 30 might lead to common side effects becoming more pronounced. If you've accidentally taken more than your prescribed dose, don't panic, but do inform your doctor about it.

Missed Dose

If you forget to take a dose of Ibiflo S 50/500 MG Nexcap 30, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never double up on doses without consulting your doctor.

Store Ibiflo S 50/500 MG Nexcap 30 at room temperature.
Keep the capsule in its original package until use to protect it from light and moisture.
Always keep Ibiflo S 50/500 MG Nexcap 30 out of reach of children.
Check the expiry date on the package and make sure to use the medicine before this date.

If you're managing asthma or COPD with Ibiflo S 50/500 MG Nexcap 30, avoid exposure to cigarette smoke. Passive smoking can worsen your condition.
Maintain a balanced diet, rich in antioxidants like fruits and vegetables. Antioxidants can help reduce inflammation in your airways.

Fact Box

Drug Category	Corticosteroid, Beta-2 agonist
Therapeutic Category	Anti-asthmatic, COPD management
Available Dosage Types	Nexcaps
Habit Forming	No
Ailment	Asthma, Chronic obstructive pulmonary disease (COPD)

What is Ibiflo S 50/500 MG Nexcap 30 used for?

Ibiflo S 50/500 MG Nexcap 30 is a medication used to manage chronic obstructive pulmonary disease (COPD) and asthma in adults by reducing airway inflammation and relaxing muscles around the airways.

How should I use Ibiflo S 50/500 MG Nexcap 30?

This medicine is for oral inhalation only. The capsules should not be swallowed but used with the inhaler device provided, delivering the medication directly into your lungs.

Can I swallow the Ibiflo S 50/500 MG Nexcap 30 capsules?

No, the capsules are not meant to be swallowed. They are designed for inhalation through the provided inhaler device to ensure effective delivery of the medicine to your lungs.

What if I miss a dose of Ibiflo S 50/500 MG Nexcap 30?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule.

Can I stop taking Ibiflo S 50/500 MG Nexcap 30 suddenly?

No, you should not stop using Ibiflo S 50/500 MG Nexcap 30 abruptly. Sudden discontinuation could worsen your COPD or asthma symptoms. Always consult your doctor before stopping any medication.

How long does it take for Ibiflo S 50/500 MG Nexcap 30 to work?

You may see improvement in symptoms within 30 minutes of taking your first dose, but regular usage over a week or longer is typically needed to achieve maximum benefit.

Are there any side effects of using Ibiflo S 50/500 MG Nexcap 30?

Side effects may include nasal inflammation, throat irritation, headache, cough, muscle pain, and oral fungal infection (thrush). If you experience any unusual symptoms, consult your doctor immediately.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

GlaxoSmithKline. (2000). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021077s029lbl.pdf
GlaxoSmithKline. (2000). HIGHLIGHTS OF PRESCRIBING INFORMATION. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021254s036lbl.pdf
DailyMed - FLUTICASONE PROPIONATE AND SALMETEROL powder, metered. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=77269609-fb89-47c7-97cc-22e0183e91ae
Fluticasone and salmeterol oral inhalation: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a699063.html
Salmeterol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00938
Fluticasone propionate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00588

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