Glipy Met 50500 Mg Tablet Sr 10

Glipy Met 500 Sr Tablet 10

Alembic Ltd

Strip of 10 Units

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₹77.44

₹9.21/Units

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Store Below 30^o C

Composition

Metformin (500 Mg) + Vildagliptin (50 Mg)

Glipy MET 500 Tablet is mainly used for managing type 2 diabetes mellitus in adults. It's a combination medicine that falls into the category of oral antidiabetic medications.

This medication is particularly beneficial for those who haven't achieved desired control over their blood sugar levels through diet, exercise and metformin alone. Apart from the main use, it also helps prevent severe complications linked with diabetes, such as kidney issues, blindness, nerve damage, limb amputations and heart problems.

Before starting this tablet, you should consult your doctor and inform him about any existing health conditions or ongoing medicines. If you notice any side effects while taking this medicine, notify your doctor right away. Make sure to continue the medicine for the duration prescribed by your doctor to achieve optimal results.

Glipy MET 500 Tablet is used for the following:

Management of type 2 diabetes mellitus in adults: This medicine is particularly helpful for those who have not achieved satisfactory blood sugar control with diet, exercise and metformin alone.
Assistance in preventing serious complications associated with diabetes: These include kidney damage, blindness, nerve problems, limb amputations, and cardiovascular issues.

Directions for Use of Glipy Met 500 Sr Tablet 10

Here's how you should take Glipy MET 500 Tablet:

Swallow the tablet whole with water.
Do not crush, chew or break the tablet.
It is advisable to take this medicine with your evening meal.
Make sure you follow the dosage as prescribed by your doctor.
Remember to continue your regular diet and exercise while taking this medication.

Glipy MET 500 Tablet is taken orally.

Side Effects of Glipy Met 500 Sr Tablet 10

While taking Glipy MET 500 Tablet, you might experience a few side effects:

Diarrhoea
Nausea and Vomiting
Abdominal Pain
Flatulence: This is a fancy term for excessive gas in your stomach or intestine.
Headache
Dizziness
Nasopharyngitis: This refers to inflammation of the nasopharynx, the upper part of your throat behind the nose.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glipy MET 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips on managing a couple of common side effects:

Diarrhoea: Try taking Glipy MET 500 Tablet with your evening meal.
Abdominal Pain: If this medication causes stomach discomfort, consider taking it after meals.

Glipy MET 500 Tablet contains two active ingredients:

Metformin (500 mg): As a biguanide medication, metformin primarily works by reducing the production of glucose in your liver. It also decreases the absorption of glucose from your gut and improves how sensitive your body's cells are to insulin. This does not promote insulin secretion, hence it's less likely to cause low blood sugar levels.
Vildagliptin (50 mg): This is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It blocks an enzyme in your body that breaks down incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By prolonging these hormones' activity, vildagliptin enhances insulin secretion from pancreatic beta-cells and suppresses glucagon secretion from pancreatic alpha-cells when glucose levels are elevated. Consequently, vildagliptin helps reduce blood sugar levels.

Pregnancy

Glipy MET 500 Tablet should be used with caution if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking this medicine if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Be cautious if consuming alcohol while taking Glipy MET 500 Tablet. Alcohol can interfere with blood sugar control in diabetes, potentially affecting the medicine's effectiveness.

Liver

Glipy MET 500 Tablet should be used with caution if you have liver problems. This medicine may affect liver function, so it's a good idea to discuss any liver-related concerns with your doctor before starting treatment.

Kidney

This medicine should be used cautiously if you have kidney problems, as metformin, one of its ingredients, is eliminated via the kidneys. Regular monitoring of kidney function is advised while taking this medicine.

Using Machines & Driving

As Glipy MET 500 Tablet may cause dizziness, caution is advised when driving or using machines until you know how this medicine affects you.

Allergy

If you're allergic to metformin, vildagliptin, or any other components in this medicine, it's important not to take Glipy MET 500 Tablet. Always inform your doctor about any known allergies before starting this medication.

Children

This medication isn't recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Glipy MET 500 Tablet under medical supervision. They may be more susceptible to its side effects and might also have liver and kidney issues. Your doctor will guide you based on your health status.

Interactions of Glipy Met 500 Sr Tablet 10

Drug-Drug Interactions

Renal function affecting medicines: Medicines like cimetidine, ranolazine, and vandetanib may interact with metformin, a component of Glipy MET 500 Tablet. This interaction could potentially increase the risk of lactic acidosis.
Strong CYP3A4 inducers: Medicines such as rifampicin can decrease the plasma concentrations of vildagliptin, another component in this medication.

Drug-Food Interactions

High-fat meals: Consuming high-fat meals while taking this medicine could impact the absorption and effectiveness of vildagliptin.

Drug-Disease Interactions

Renal Impairment: As metformin is primarily eliminated via the kidneys, patients with kidney disease should use this medication cautiously.
Severe Hepatic Impairment: This medicine should not be used by individuals with severe liver disease as it could exacerbate their condition.

Daily Dose

The daily dosage of Glipy MET 500 Tablet should be as prescribed by your doctor. This can vary depending on factors like the severity of your condition and your response to the medication. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you unintentionally take more than the prescribed dose of Glipy MET 500 Tablet, you may experience overdose symptoms like nausea, vomiting, or diarrhoea. If these symptoms persist or worsen, kindly inform your doctor.

Missed Dose

If you forget to take your regular dose of Glipy MET 500 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your usual dosage schedule. Never adjust your dosage without consulting your doctor.

Store Glipy MET 500 Tablet at room temperature, ideally below 30°C.
Keep the medicine protected from light and moisture.
Always keep this medicine out of reach of children.
Use the tablet before its expiry date.

Regular physical activity is beneficial. Try to incorporate moderate exercise, such as walking or cycling, into your daily routine. This can help control blood sugar levels.
Opt for a balanced diet rich in fiber and low in refined sugars. Include whole grains, fruits, vegetables, and lean proteins to support management of type 2 diabetes.

Fact Box

Drug Category	Biguanide, DPP-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Glipy MET 500 Tablet used for?

It's used to manage blood sugar levels in adults with type 2 diabetes who haven't achieved satisfactory control with diet, exercise, and metformin alone.

How does Glipy MET 500 Tablet work?

It combines two active ingredients to regulate blood glucose. Metformin reduces glucose production and absorption, while vildagliptin enhances insulin secretion and reduces glucagon secretion.

When should I take Glipy MET 500 Tablet?

Typically, it's taken once daily with the evening meal. Remember not to crush or chew it; swallow the tablet whole.

What are the common side effects of Glipy MET 500 Tablet?

Common side effects can include nausea, diarrhoea, vomiting, abdominal pain, flatulence, headache, dizziness, and nasopharyngitis.

Are there any precautions I should take while using Glipy MET 500 Tablet?

Yes, it's contraindicated for individuals with hypersensitivity to metformin or vildagliptin, renal impairment, type 1 diabetes, diabetic ketoacidosis, or severe hepatic impairment.

Can other medicines affect how Glipy MET 500 Tablet works?

Yes, certain medications that affect renal function or compete for renal tubular secretion can interact with metformin. Always consult your doctor before starting new medication.

How should I store Glipy MET 500 Tablet?

Store it below 30°C in a dry place, protected from light and moisture. Keep the medicine out of reach of children and pets.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Eucreas. (n.d.). Eucreas Summary of product characteristics. https://www.ema.europa.eu/en/documents/product-information/eucreas-epar-product-information_en.pdf
Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
NVR & FB. (2020). Galvus. In Galvus (pp. 1–19). https://www.novartis.com/sg-en/sites/novartis_sg/files/Galvus-Jul2020.SIN-App051120.pdf
Vildagliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04876

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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