Gastrogyl 250300 Mg Tablet 10

Gastrogyl 250/300 MG Tablet 10

Biological E Ltd

Pack of 10 Units

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Composition

Ciprofloxacin (250 Mg) + Tinidazole (300 Mg)

Gastrogyl 250/300 MG Tablet 10 is primarily used to manage various bacterial and parasitic infections. This combination medicine falls under the category of antibiotics.

In addition to its main use, this medicine is also prescribed for conditions such as bacterial gastroenteritis and diarrhoea, giardiasis and amoebiasis, gynaecological infections like bacterial vaginosis and trichomoniasis, respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections, amongst others.

Before you start taking this medicine, it's essential to consult your doctor about the right dosage and frequency for you. Make sure to inform your doctor about any preexisting conditions or ongoing medications. If you experience any side effects while on this medicine, notify your doctor immediately. It's important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Gastrogyl 250/300 MG Tablet 10 is commonly used to manage the following conditions:

Management of bacterial gastroenteritis and diarrhoea.
Control of giardiasis and amebiasis.
Management of gynaecological infections like bacterial vaginosis and trichomoniasis.
Handling intraabdominal infections.
Management of respiratory tract infections.
Control of urinary tract infections.
Management of skin and soft tissue infections.
Handling bone and joint infections.
Prevention of infections during surgery.

Directions for Use of Gastrogyl 250/300 MG Tablet 10

Here are the general instructions for taking Gastrogyl 250/300 MG Tablet 10:

Swallow the tablet whole with a glass of water.
Take the tablet with food to minimise possible stomach upset.
Avoid breaking or chewing the tablet before consuming it.
Do not take more than recommended by your doctor.
For specific directions related to your condition, always consult your doctor.

Gastrogyl 250/300 MG Tablet 10 is taken orally.

Side Effects of Gastrogyl 250/300 MG Tablet 10

Gastrogyl 250/300 MG Tablet 10 may cause the following side effects:

Nausea
Diarrhoea
Abdominal pain
Dyspepsia: This refers to indigestion or discomfort in the stomach.
Metallic taste in the mouth: You might notice a strange, unpleasant taste.
Skin rash and itching
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gastrogyl 250/300 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Increase your water intake and consume plenty of healthy fluids to stay hydrated.
Dyspepsia: If you have indigestion, taking this medicine after light meals might lessen this effect.

How Gastrogyl 250/300 MG Tablet 10 Works?

Gastrogyl 250/300 MG Tablet 10 contains two active ingredients:

Ciprofloxacin (250 mg): This fluoroquinolone antibiotic works by inhibiting two enzymes in your body DNA gyrase and topoisomerase IV. These enzymes are crucial for bacterial DNA replication and cell division. By blocking these enzymes, Ciprofloxacin effectively hampers the growth and multiplication of bacteria.
Tinidazole (300 mg): As a nitroimidazole antibiotic and antiprotozoal agent, Tinidazole acts by causing damage to the DNA of anaerobic bacteria and protozoa which leads to their cell death. Tinidazole is particularly effective against certain parasites like Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia.

Pregnancy

Caution is advised while taking Gastrogyl 250/300 MG Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Gastrogyl 250/300 MG Tablet 10 is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Consuming alcohol during treatment with Gastrogyl 250/300 MG Tablet 10 and for at least 3 days after completing the course is not recommended due to a possible reaction with Tinidazole.

Liver

Caution is advised while taking Gastrogyl 250/300 MG Tablet 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before using Gastrogyl 250/300 MG Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause dizziness or drowsiness; exercise caution when driving or operating machinery.

Allergy

Gastrogyl 250/300 MG Tablet 10 should not be taken if you are allergic to Ciprofloxacin, Tinidazole, or any other quinolone or nitroimidazole antibiotics. If you know you have such allergies, inform your doctor.

Children

Gastrogyl 250/300 MG Tablet 10 is an adult formulation and should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Gastrogyl 250/300 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Gastrogyl 250/300 MG Tablet 10

Drug-Drug Interactions

Gastrogyl 250/300 MG Tablet 10 interacts with the following medicines:

Antacids and supplements (e.g., magnesium or aluminium-containing antacids, calcium, iron supplements): These can reduce the absorption of Ciprofloxacin, leading to decreased effectiveness.
Blood thinners (e.g., Warfarin): Tinidazole can enhance the effects of warfarin, increasing the risk of bleeding. Ciprofloxacin may also potentiate this effect.
Antiarrhythmics (e.g., Amiodarone, Quinidine): Ciprofloxacin can prolong the QT interval, potentially leading to serious heart rhythm problems when combined with these medicines.

Drug-Food Interactions

Gastrogyl 250/300 MG Tablet 10 interacts with dairy products such as milk and cheese. These foods may decrease the absorption of Ciprofloxacin.

Drug-Disease Interactions

Gastrogyl 250/300 MG Tablet 10 interacts with the following diseases:

Epilepsy: If you have epilepsy or other seizure disorders, this medicine could exacerbate your condition due to its interaction with Ciprofloxacin.
Liver disease: Gastrogyl 250/300 MG Tablet 10 should be used cautiously if you have liver disease as it can further strain your liver function.
Myasthenia gravis: This medicine could worsen muscle weakness in people with myasthenia gravis due to its interaction with Ciprofloxacin.
QT prolongation: This medicine should be used carefully in those with a history of QT prolongation as it might increase the risk of serious heart rhythm problems.

Dosage of Gastrogyl 250/300 MG Tablet 10

Daily Dose

The daily dose of Gastrogyl 250/300 MG Tablet 10 is dictated by your doctor, who adjusts it based on your response to treatment and the severity of your condition. Always follow the prescribed dosage without exceeding it unless advised by your doctor.

Over Dose

In the event of an overdose, common symptoms could include feeling unwell or experiencing a mild stomach upset. Remember, excessive intake of this medicine won't speed up recovery but might increase side effects. If you're feeling unwell after taking more than the prescribed dose, let your doctor know.

Missed Dose

If you forget to take Gastrogyl 250/300 MG Tablet 10 when you should, take it as soon as you remember. But if it's nearly time for the next dose, just skip the missed one and stick to your regular schedule. Always consult your doctor before altering your dosage.

Store Gastrogyl 250/300 MG Tablet 10 at room temperature.
Keep the medicine in a dry place, away from excess heat and direct sunlight.
Avoid moisture and do not store in damp areas such as bathrooms.
Keep this medicine out of reach of children.
Always use the product before the expiry date printed on the packaging.

As Gastrogyl 250/300 MG Tablet 10 is used to manage bacterial and parasitic infections, maintaining proper hygiene is essential. Regularly washing your hands, especially before meals, can help prevent infection spread.
Since alcohol consumption can cause adverse reactions with this medicine, it's recommended that you abstain from alcohol during your course of treatment, and for three days after completion.

Fact Box

Drug Category	DNA Synthesis Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Giardiasis

What is Gastrogyl 250/300 MG Tablet 10 used for?

Gastrogyl 250/300 MG Tablet 10 is used to manage various bacterial and parasitic infections including gastroenteritis, urinary tract infections, and gynaecological infections.

How does Gastrogyl 250/300 MG Tablet 10 work?

This medicine contains two active ingredients ciprofloxacin and tinidazole. Both disrupt the DNA of bacteria and parasites, preventing them from growing and multiplying.

Can I take Gastrogyl 250/300 MG Tablet 10 on an empty stomach?

You must take the medicine exactly as prescribed by your doctor.

What should I do if I forget to take a dose of Gastrogyl 250/300 MG Tablet 10?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one. Don't double up doses.

Can I drink alcohol while taking Gastrogyl 250/300 MG Tablet 10?

No, drinking alcohol while taking this medicine and for three days after finishing the course can cause unpleasant symptoms like nausea, vomiting, or rapid heartbeat.

What are some common side effects of Gastrogyl 250/300 MG Tablet 10?

Common side effects may include nausea, vomiting, abdominal pain, headache, dizziness, and a metallic taste in your mouth.

Should I stop taking Gastrogyl 250/300 MG Tablet 10 once my symptoms improve?

No, you should complete the entire course prescribed by your doctor even if your symptoms improve earlier to prevent the infection from returning.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

National Agency for Food & Drug Administration & Control (NAFDAC). (n.d.). SUMMARY OF PRODUCT CHARACTERISTICS (SMPC) TEMPLATE. In Registration & Regulatory Affairs (R & R) Directorate (Cipnox Plus). https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/January_2023_Revised/CIPNOX-PLUS-TABLETS.pdf
HIGHLIGHTS OF PRESCRIBING INFORMATION. (1987). [Prescribing information; Tablet, for oral use]. In CIPRO. Bayer HealthCare Pharmaceuticals Inc. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019537s086lbl.pdf
Ciprofloxacin: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00537
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2004). [Prescribing information]. In Tindamax. https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021618s003lbl.pdf
Tinidazole: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00911

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