Aprezo 30 Mg Tablet 10

Aprezo 30 Tablet 10

Glenmark Pharmaceuticals Ltd.

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Composition

Apremilast (30 Mg)

Aprezo 30 Tablet is a medicine used to manage certain skin and joint conditions. It helps with plaque psoriasis, psoriatic arthritis, and oral ulcers caused by Behcet's disease.

When using Aprezo 30 Tablet, it is important to follow the prescribed dosage. Swallow the tablet whole with a glass of water. Read the instructions on the prescription label and consult your doctor if you have any questions.

It may take several months for the complete effectiveness of the medicine to show. At the same time, continue taking this medicine as prescribed even if you start feeling better. Stay hydrated by drinking plenty of water and avoid alcohol while on this treatment.

Please note that Aprezo 30 Tablet may not be suitable for everyone. Talk to your doctor about any gut problems, intolerance to certain sugars, kidney problems, or liver problems before taking this medicine.

Aprezo 30 Tablet uses include the management of the following conditions:

Plaque psoriasis: Chronic skin condition with red, scaly, itchy, and painful patches on the skin.
Psoriatic arthritis: Arthritis that affects individuals with psoriasis, causing joint inflammation and pain.
Oral ulcers caused by Behcet's disease: Rare inflammatory condition resulting in mouth ulcers.

Take Aprezo 30 Tablet as prescribed by your doctor.
Swallow the tablet whole with a glass of water.
Do not crush, chew, or break the tablet.
Follow the instructions on your prescription label.
Take it at the same time every day to maintain consistency.
Consult your doctor before making any changes to your dosage or treatment plan.

Aprezo 30 Tablet is taken orally, which means you swallow it with water. It is not to be used topically or injected.

Taking Aprezo 30 Tablet may cause certain side effects. Here are a few common ones:

Nausea
Diarrhoea
Vomiting

It's important to note that these side effects are usually mild and may go away on their own as your body adjusts to the medicine.

Managing the Side Effects:

If you experience any of these side effects while taking Aprezo 30 Tablet, here are some natural ways to manage them:

Nausea: Try eating smaller, more frequent meals throughout the day and avoid greasy or spicy foods.
Diarrhoea: Stay hydrated and consume foods that are gentle on your stomach, such as plain rice or bananas.
Vomiting: Take small sips of clear liquids, such as water or ginger ale, and rest until you feel better.

Remember, if these side effects persist or worsen, it is important to consult your doctor for further guidance.

Aprezo 30 Tablet contains apremilast as its active ingredient.

Apremilast works by blocking certain chemical messengers responsible for inflammation associated with psoriatic arthritis and psoriasis.
By reducing inflammation, Aprezo 30 Tablet helps alleviate the signs and symptoms of these conditions.
It targets specific enzymes called phosphodiesterase 4 (PDE4) inhibitors to regulate the immune response in the body.
This regulation helps in reducing redness, scaling, itching, pain, joint inflammation, and mouth ulcers.

Pregnancy

If you are pregnant or planning to become pregnant, consult your doctor before taking Aprezo 30 Tablet. Limited studies in humans have shown harmful effects on the developing baby.

Breastfeeding

Aprezo 30 Tablet is not recommended while breastfeeding. Consult your doctor before using this medicine if you are nursing your baby.

Alcohol

Exercise caution when consuming alcohol while taking Aprezo 30 Tablet. It is best to consult your doctor before consuming alcohol during the treatment.

Liver

Inform your doctor if you have any liver problems before starting Aprezo 30 Tablet.

Kidney

Let your doctor know if you have any kidney issues before taking Aprezo 30 Tablet.

Using Machines & Driving

Aprezo 30 Tablet is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid such activities and consult your doctor.

Allergy

If you have known allergies to any components of Aprezo 30 Tablet, inform your doctor before using it.

Children

Aprezo 30 Tablet is not recommended for use in children. Consult a paediatrician for suitable alternatives if needed.

Older Patients

Caution should be exercised in elderly patients when using Aprezo 30 Tablet. Regular monitoring may be required by the treating physician.

Drug-Drug Interactions

Here are some categories of drugs that may interact with Aprezo 30 Tablet:

Immunosuppressants: Methotrexate, cyclosporine
Biologic agents: Adalimumab, infliximab
CYP3A4 inhibitors: Ketoconazole, clarithromycin
CYP3A4 inducers: Carbamazepine, rifampin
OAT3 inhibitors: Probenecid

Drug-Food Interactions

There are no known specific food or beverage interactions with Aprezo 30 Tablet.

Drug-Disease Interactions

Individuals with a history of depression or suicidal thoughts should exercise caution when taking Aprezo 30 Tablet, as it may worsen these conditions.
Patients with severe kidney or liver problems should consult their doctor before using Aprezo 30 Tablet.
Aprezo 30 Tablet is not recommended for use in patients with severe gastrointestinal disorders.

Please note that these interactions are based on the details provided and may not be exhaustive. It is important to inform your doctor about all the medications you are taking and any existing medical conditions before starting Aprezo 30 Tablet.

Daily Dose

Take Aprezo 30 Tablet as prescribed by your doctor. The usual dose is twice a day, at the same time every day. Your doctor may adjust the dose based on your condition and response to treatment. Take it with or without food.

Over Dose

Taking too many tablets can lead to serious side effects. If you accidentally take too much, seek immediate medical attention. Contact your doctor or go to a nearby hospital.

Missed Dose

If you forget to take Aprezo 30 Tablet as instructed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Aprezo 30 Tablet in a cool, dry place.
Protect it from light and moisture to maintain its effectiveness.
Keep the medicine out of the reach of children and pets.
Use the product before the expiry date mentioned on the packaging.

Maintain a balanced diet with plenty of fruits and vegetables.
Stay hydrated by drinking enough water throughout the day.
Engage in regular exercise to support overall health.
Avoid excessive alcohol consumption while using Aprezo 30 Tablet.
If indicated for paediatric use, ensure your child follows a healthy diet and gets regular physical activity.
Follow any additional dietary or lifestyle recommendations provided by your doctor or healthcare professional.

Take Aprezo 30 Tablet as prescribed by your doctor.
Avoid crushing or breaking the tablets; swallow them whole with water.
Be patient, as it may take time for the medicine to show its full effectiveness.
If you experience any side effects, inform your doctor immediately.
Do not stop taking the medicine without consulting your doctor.

Fact Box

Drug Category	Phosphodiesterase 4 (PDE4) inhibitor
Therapeutic Category	Dermatological and rheumatological disorders
Available Dosage Types	Tablets
Habit Forming	Non-addictive
Ailment	Plaque psoriasis, psoriatic arthritis, Behcet's disease

What conditions can Aprezo 30 Tablet be used for?

Aprezo 30 Tablet is used to manage three conditions: plaque psoriasis, psoriatic arthritis, and oral ulcers caused by Behcet's disease. Plaque psoriasis is a chronic skin condition characterized by red, scaly, itchy, and painful patches on the skin. Psoriatic arthritis is a type of arthritis that affects individuals with psoriasis, causing joint inflammation and pain. Behcet's disease is a rare inflammatory condition that can lead to mouth ulcers.

How does Aprezo 30 Tablet help in these conditions?

Aprezo 30 Tablet helps reduce the symptoms associated with plaque psoriasis, psoriatic arthritis, and oral ulcers caused by Behcet's disease. It alleviates redness, scaling, itching, pain, joint inflammation, and mouth ulcers. However, it may take several months for the full effectiveness of the medicine to show. Remember to stay hydrated by drinking plenty of water and avoid consuming alcohol while on this treatment.

How should I take Aprezo 30 Tablet?

Aprezo 30 Tablet is taken orally in the form of tablets. The recommended dosage is twice a day at the same time every day. Swallow the tablets whole with a glass of water; do not crush, chew, or break them. Follow the instructions on your prescription label and consult your doctor if you have any questions.

How does Aprezo 30 Tablet work?

Aprezo 30 Tablet belongs to a class of drugs called phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers responsible for inflammation associated with psoriatic arthritis and psoriasis. By reducing inflammation, it helps alleviate the signs and symptoms of these conditions.

What are the common side effects of Aprezo 30 Tablet?

Common side effects of Aprezo 30 Tablet include nausea, diarrhoea, and vomiting. These side effects are usually mild and may subside as the body adjusts to the medication. If they persist or worsen, inform your doctor.

Are there any precautions I should take while using Aprezo 30 Tablet?

Exercise caution when consuming alcohol while taking Aprezo 30 Tablet and consult your doctor before doing so. It may be unsafe to use during pregnancy, so consult your doctor if you are pregnant or planning to become pregnant. It is not recommended for use during breastfeeding; consult your doctor before using this medication if you are breastfeeding. Aprezo 30 Tablet is not recommended for use in children and adolescents.

How should I store Aprezo 30 Tablet?

Store Aprezo 30 Tablet in a cool and dry place away from direct sunlight to maintain its effectiveness.

Last Updated On 12 Sep. 2023 | 4:36PM (IST)

Certified Content

Written by

Bhavya Mehta

Scientific & Medical Writer | 3 years

M.Sc. Biological Sciences

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Griffiths, C. E. M., Creamer, D., Barker, J., Chalmers, R., & Bleiker, T. O. (2016). Plaque psoriasis, psoriatic arthritis, Atopic Eczema. Rook's Textbook of Dermatology (9th ed., pp. 1161, 1177, 1296).
Zerilli, T., & Ocheretyaner, E. (2015). Apremilast (Otezla): A New Oral Treatment for Adults with Psoriasis and Psoriatic Arthritis. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517531/
Amgen Europe B.V. (2021). Electronic Medicines Compendium (EMC). Retrieved from https://www.medicines.org.uk/emc/files/pil.3648.pdf
Apremilast: MedlinePlus Drug Information. (n.d.). MedlinePlus. Retrieved from https://medlineplus.gov/druginfo/meds/a614022.html
Clinical Pharmacology Review: Apremilast. (2014). FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205437Orig1s000ClinPharmR.pdf

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