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Clobetasol + Gentamicin + Miconazole

Uses of Clobetasol + Gentamicin + Miconazole

  • The main use of Clobetasol + Gentamicin + Miconazole is to manage mixed fungal, bacterial, and inflammatory skin conditions. It belongs to the class of potent corticosteroids, aminoglycoside antibiotics, and imidazole antifungals.

  • Secondary uses of this combination medicine include the management of infected eczema, inflamed ringworm (tinea corporis), inflamed jock itch (tinea cruris), inflamed athlete's foot (tinea pedis), and other mixed skin infections with secondary inflammation.

Side effects of Clobetasol + Gentamicin + Miconazole

  • Burning or stinging sensations

  • Itching or redness

  • Dryness or peeling skin

  • Skin irritation or rashes

  • Hives

How Clobetasol + Gentamicin + Miconazole works

  • Clobetasol + Gentamicin + Miconazole is a comprehensive topical medication.

  • Clobetasol, part of the corticosteroid family, works by suppressing the immune response, specifically reducing the production of certain chemical messengers (prostaglandins and leukotrienes) in the body that cause inflammation, swelling and itching on the skin.

  • Gentamicin, an antibiotic, operates by attaching to bacterial proteins and disturbing their manufacturing process. This disrupts normal bacterial function, causing the bacteria to perish.

  • Miconazole, an antifungal agent, obstructs the production of a substance called ergosterol which is crucial for the fungal cell membrane. As a result, holes appear in this membrane, leading to the leakage of necessary components and the ultimate death of the fungal cells.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Clobetasol + Gentamicin + Miconazole is available via topical route ( cream, ointment, and lotion).

Age and Dose Restrictions

  • This medicine is meant for use in adults and children over the age of twelve years.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to any component of the medication. It is also contraindicated in viral skin infections such as herpes, chickenpox, or shingles.

Other Medications to Avoid

  • This combination may interact with oral corticosteroids (such as prednisone and dexamethasone). Before starting any prescription or over-the-counter medications, it is crucial to consult a doctor, as using other topical corticosteroids or antibiotics with Clobetasol + Gentamicin + Miconazole might lead to increased effects.

Overdose and Missed Dose

  • An overdose of Clobetasol + Gentamicin + Miconazole may lead to excessive skin thinning, weakening of the skin's natural defences, or increased risk of systemic side effects. If you suspect an overdose, wash the area with mild soap and water and consult your doctor.

  • If you miss a dose of this medicine, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medicine to make up for a missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing dryness or peeling, consider applying the medication at a different time of day when you can allow the treatment area to air out without cover.

  • For mild irritation or redness, ensure application is thin and even; do not rub aggressively.

Use in Driving and Operating Machinery

  • Clobetasol + Gentamicin + Miconazole does not impair your ability to drive or operate machinery. However, caution should be taken to avoid getting the medication in your eyes or on other sensitive areas that might distract you while engaging in such activities.

Use in Pregnancy and Lactation

  • The use of Clobetasol + Gentamicin + Miconazole during pregnancy and breastfeeding is not recommended unless clearly needed. Consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with extensive burns or wounds should exercise caution when using this medicine due to the potential for increased systemic absorption of corticosteroids.

  • Caution is advised for patients who have a history of hypersensitivity reactions to similar medications.

Special Dietary and Lifestyle Recommendations

  • Maintain good hygiene in affected areas; keep the skin clean and dry to help reduce fungal growth and bacterial colonisation.

  • Wear breathable clothing to prevent moisture build-up, which can exacerbate skin infections.

  • Manage stress levels as high stress can negatively affect immune function and exacerbate inflammation.

  • For those dealing with infected eczema or athlete’s foot, avoid sharing personal items like towels or shoes that can spread fungi and bacteria.

  • Ensure to follow proper handwashing techniques especially after applying the medication to prevent spreading infection to other body parts or individuals.

Frequently asked questions

No, the combination of Clobetasol + Gentamicin + Miconazole is not a steroid.

Clobetasol + Gentamicin + Miconazole should not be used on large areas of the body or under occlusive dressings unless directed by a doctor, as this increases systemic absorption.

Yes, Clobetasol + Gentamicin + Miconazole may temporarily stain your skin, hair, or fabrics.

Systemic effects of corticosteroid absorption, such as weight gain and mood changes, are rare but can occur with prolonged use or improper application.

Clobetasol + Gentamicin + Miconazole does not affect male or female fertility.

You should continue using Clobetasol + Gentamicin + Miconazole for the full duration prescribed by your doctor, even if your symptoms improve before the end of the treatment course.

No, Clobetasol + Gentamicin + Miconazole usually requires a prescription and is not available over the counter.

Terms & Conditions


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