Tretin 0.025% Cream 30gm

Hegde & Hegde

Tube of 30 GM

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Composition

Tretinoin (0.025 %)

Strength:

0.05 %0.025 %

Tretin 0.025% or Tretinoin cream is used to treat acne, fine wrinkles, dark spots, and other skin conditions as advised by your doctor. It is a form of vitamin A that works by increasing skin cell turnover, helping to unclog pores and reduce acne formation. Additionally, it is effective in treating rough skin, fine wrinkles, and dark spots caused by sun damage. One common composition is Tretin 0.025% cream. It is available in various forms, including creams, gels, and lotions. It can take several weeks or months to see the full effects of Tretinoin, and it may cause some side effects, such as skin irritation and dryness.

Tretin 0.025% cream composition: Tretin cream contains the active ingredient Tretinoin in a concentration of 0.025%. Tretinoin is a member of the retinoid class of drugs and is a derivative of vitamin A.

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Tretin 0.025% Cream is used to treat acne, fine wrinkles, dark spots, and skin damage from the sun. It helps reduce hyperpigmentation, melasma, and rough skin texture. The cream is also effective for conditions like stretch marks, ichthyosis (dry, scaly skin), rosacea (redness and pimples on the face), keratosis pilaris (bumpy skin), and photoaging (premature aging from sun exposure). Additionally, it prevents new acne breakouts, improves skin texture, and enhances overall skin appearance.

Directions for Use of Tretin 0.025% Cream 30gm

The medicine Tretin 0.025% cream is often applied topically on the skin's affected areas. But following these steps, you can avail better results from this ointment:

Wash your skin: If you have irritating skin, use a mild cleanser to wash it before using Tretinoin, then pat it dry.
Apply a thin layer: Apply a pea-sized amount of Tretin 0.025% cream to the affected area, such as the mucous membrane, keeping the eyes, mouth, and nostrils out of the way.
Prevent sensitive areas: To reduce the risk of skin irritation, avoid using Tretinoin on irritated, sunburned, or damaged skin.
Be patient and keep using Tretin 0.025% cream as your doctor has instructed until you identify a noticeable improvement in your skin condition, which could take many weeks or months.
To prevent further harm to your skin during the day, use sunscreen with a minimum SPF of 30 and wear protective clothing. You must stop using Tretin 0.025% cream and speak with your doctor if you get severe skin rashes or allergic reactions.
Tretin 0.025% cream is commonly used at night time since exposure to sunshine can increase your skin's sensitivity to the medicine.

Tretin 0.025% cream is administered topically, which means it is placed on the skin's surface and absorbed through the epidermis into the tissues beneath.

Side Effects of Tretin 0.025% Cream 30gm

It’s better to consult a doctor before using Tretin 0.025% cream. Here are some common side effects of Tretin 0.025% cream:

Skin irritation: This is the most common side effect of Tretin 0.025% cream, characterised by redness, dryness, peeling, and skin flaking.
Sensitivity to sunlight: Tretin 0.025% cream can increase the skin's sensitivity to sunlight, making it more prone to sunburn and other skin damage.
Burning or stinging feeling: Some people may experience a burning or stinging sensation when using Tretin Cream, especially during the first few weeks of treatment.
Itching or scratchy skin: Tretin 0.025% cream can also cause the skin to feel itchy or scratchy, which can be uncomfortable.
Skin colour change: In some cases, Tretin Cream may cause changes in skin colour, including darkening or lightening of the skin.
Dryness: Tretin 0.025% cream can dry out the skin, making it feel tight and uncomfortable.
Peeling: Tretin 0.025% cream can cause the skin to peel, which can be unpleasant and uncomfortable.
Rash: Some people may develop a rash or hives when using Tretin Cream, which can be a sign of an allergic reaction.
Acne flare-ups: In some cases, Tretin Cream may cause acne flare-ups, especially during the first few weeks of treatment.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing Tretin 0.025% cream. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Tretin 0.025% cream works by increasing the turnover rate of skin cells. Tretinoin helps to regulate the growth and differentiation of skin cells by binding to specific receptors on the surface of skin cells. This increases the rate at which skin cells are shed and new cells are produced, which helps to unclog pores and reduce the formation of acne. Tretinoin also helps to improve the appearance of wrinkles and dark spots on the skin by stimulating collagen production.
In addition to regulating skin cell growth and differentiation, Tretinoin also has anti-inflammatory properties that can help to reduce the redness and swelling associated with acne.

Pregnancy

Tretin 0.025% cream should be used with caution during pregnancy, as it may harm the developing foetus. If you're pregnant or planning to become pregnant, it's important to talk to your healthcare provider before using tretin cream.

Breastfeeding

It's not known whether tretin cream passes into breast milk. If you're a breastfeeding mother, it's important to talk to your healthcare provider before using tretin cream.

Alcohol

There are no known interactions between tretin cream and alcohol. However, excessive alcohol consumption can increase the risk of skin irritation and dryness, which may worsen the side effects of Tretin 0.025% cream.

Liver

There are no specific precautions for using tretin cream in patients with liver disease. However, patients with liver disease may be more susceptible to skin irritation and other side effects of tretin cream.

Kidney

There are no specific precautions for using Tretin 0.025% cream in patients with kidney disease. But it’s always best to consult a doctor before using the medication.

Using Machines & Driving

Tretin 0.025% cream is not known to affect a person's ability to use machines or drive.

Allergy

If you are allergic to tretin cream or any of its ingredients, do not use this medication. Be sure to tell your healthcare provider if you have any known allergies before using tretin cream.

Children

Tretin 0.025% cream should not be used in children under 12 years of age without the advice of a healthcare provider.

Older Patients

Tretin cream can be used in older patients, but they may be more susceptible to skin irritation and other side effects. Healthcare providers may adjust the dosage or closely monitor older patients while using tretin cream.

Interactions of Tretin 0.025% Cream 30gm

Drug-Drug Interactions

Avoid using Tretin cream with other topical medications that can cause skin irritation, such as benzoyl peroxide, salicylic acid, or sulphur-containing products, as this may worsen skin irritation.
Tretin cream may interact with other topical medications containing retinoids, such as adapalene, tazarotene, or isotretinoin, increasing the risk of skin irritation, dryness, or redness.
Tretin cream may increase the risk of sunburn when used in combination with other medications that make the skin more sensitive to sunlight, such as tetracyclines, sulfa drugs, or thiazides.
Taking oral vitamin A supplements with Tretin cream may increase the risk of vitamin A toxicity.
Oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone) will interact with Tretin 0.025% cream. So it should be avoided while using Tretin cream.
Tretin cream may interact with tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Monodox, Vibramycin, others), minocycline (Minocin), oxytetracycline (Terramycin), and tetracycline (Sumycin, Tetrex, others). It may also interact with tranexamic acid (Cyklokapron)

Drug-Food Interactions

There are no known significant interactions between Tretin cream and specific foods. However, consuming foods high in vitamin A (such as carrots, sweet potatoes, and spinach) in excessive amounts while using Tretin cream may increase the risk of vitamin A toxicity.

Drug-Disease Interactions

Individuals with eczema or atopic dermatitis may be more prone to developing skin irritation or allergic reactions when using Tretin cream.
Tretin 0.025% cream may increase skin sensitivity and worsen symptoms in individuals with sunburn, windburn, or other skin irritations. It is recommended to wait until the skin has fully healed before using Tretin cream.

Daily Dose

The dosage of Tretin 0.025% cream depends on the condition being treated and the severity of the condition. Typically, for the treatment of acne vulgaris or fine wrinkles, a pea-sized amount of cream is applied once daily to the affected area, usually in the evening. The cream should be applied to clean, dry skin, and it is important to avoid applying the cream to areas around the eyes, mouth, and nose.

Over Dose

Using too much Tretin 0.025% cream can cause skin irritation, redness, peeling, and discomfort. If you accidentally apply too much Tretin cream, simply wash off the excess with mild soap and water. If you experience severe skin irritation, seek medical attention.

Missed Dose

If you miss a dose of Tretin cream, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Don't apply extra cream to make up for the missed dose.

In order to ensure the safety and effectiveness of the Tretin cream, it needs to be properly maintained.
Tretin 0.025% cream should be kept at a room temperature (20°C - 25°C).
Don't keep it in extreme heat or cold.
Tretin cream needs to be stored in a dry environment to avoid the medication being harmed by moisture.
When taking tretin cream, check the expiration date and discard any expired medication.

Protect Your Skin From Sunburn: Wear protective clothing and apply sunscreen daily with at least SPF 30 to protect your skin from the sun. Skin needs protection from sunburn. Tretinoin can make your skin more sensitive to the sun.
Avoid harsh skin care products: While using tretinoin, your skin may become irritated by products containing alcohol, astringents, or exfoliating agents. Use moisturisers and cleansers that are mild instead.
Moisturise and Hydrate: Tretinoin might cause your skin to dry; therefore, it's crucial to apply a decent moisturiser regularly. Drink enough water to maintain good skin health and prevent dryness and irritation.
Get Good Sleep: Your body can heal and rejuvenate your skin with adequate restful sleep. Avoid smoking and drinking too much alcohol, as these behaviours can harm your skin and reduce the effectiveness of tretin cream.
In general, living a healthy lifestyle and taking care of your skin can boost the effectiveness of tretin cream and keep your skin looking its best.

Tretin cream should only be used at night because sunshine can make the drug more irritating to your skin. Also, sunlight is not suitable for acne in general too.
To cover your entire face, apply a small amount of tretin cream.
If tretin cream gets in your mouth, nose, or eyes, it could irritate you. Take caution not to use it in these places.
Tretin cream can dry out your skin; therefore, after using it, it is important to moisturise your skin in order to keep it hydrated.
Waxing and other hair removal procedures should be avoided while using tretin cream since it can make your skin more sensitive.

Fact Box

Drug Category	Vitamin A supplement
Therapeutic Category	Topical acne treatment
Available Dosage Types	Cream
Habit Forming	No
Ailment	Tretin cream is used to treat acne and to improve the appearance of fine wrinkles, dark spots, and rough skin.

What is the use of Tretin 0.025% Cream?

Tretin 0.025% Cream is used to treat acne and improve skin texture by keeping pores clear. It also reduces fine wrinkles, dark spots, and rough skin caused by sun damage. It promotes skin cell turnover, enhancing skin tone and clarity with regular use under medical supervision.

What negative effects might tretin 0.025% cream cause?

The most frequent side effects of using tretin 0.025% cream are skin discolouration, itching, burning, and skin that is red, dry, peeling, and stinging.

How should I apply tretin 0.025% cream?

Tretin 0.025% cream is typically applied on clean, dry skin once daily, preferably at night. It's crucial to adhere to your healthcare provider's directions carefully.

How long does it take for Tretin 0.025% cream to produce results?

The usage of tretin 0.025% cream can take many weeks before noticeable improvements are seen. To get the best outcomes, taking the drug consistently and according to the directions is crucial.

Can those with sensitive skin use tretin 0.025% cream?

Those with sensitive skin can use tretin 0.025% cream, but there is a risk of irritation, dryness, and other negative effects. Tretin cream may need to be used at a lower concentration on individuals with sensitive skin.

Can you use tretin 0.025% cream while nursing or when pregnant?

tretin 0.025% cream should not be used during pregnancy or nursing since it could affect the developing foetus or newborn. Before taking Tretinoin or other medicine, women expecting pregnancy or nursing should consult or visit their doctor for guidance, since no research is available.

Last Updated On 05 Feb. 2025 | 12:17PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

301, Om Chambers, 123, August Kranti Rd, Babulnath, Kemps Corner, Malabar Hill, Mumbai, Maharashtra 400036

Country of origin: INDIA

References

Tretinoin (Emollient) Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD. (n.d.). https://www.webmd.com/drugs/2/drug-12141/tretinoin-emollient-topical/details
Tretinoin 0.025 % Topical Cream: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD. (n.d.). https://www.webmd.com/drugs/2/drug-3956/tretinoin-topical/details/list-conditions
Pietrangelo, A. (2023, February 1). What Are the Benefits and Side Effects of Using Tretinoin? Healthline. https://www.healthline.com/health/skin/tretinoin
Eske, J. (2024, January 23). Tretinoin: Benefits, uses, side effects, and how it compares to retinol and adapalene. https://www.medicalnewstoday.com/articles/tretinoin

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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