Nebider H 5/12.5 MG Tablet 10

Elder Prroject Limited

Strip of 10 Units

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MRP ~~₹150.00~~

₹74.85

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Composition

Hydrochlorothiazide (12.5 Mg) + Nebivolol (5 Mg)

Nebider H 5/12.5 MG Tablet 10 is primarily used to manage high blood pressure, also known as hypertension. It's a combination medicine that falls into the category of antihypertensives.

Aside from its main use, this medicine is also particularly beneficial when either one of the components alone is not sufficient to control hypertension. The combination of two antihypertensive agents in this medication allows for better blood pressure management compared to using just one component.

Consult your doctor for the right dosage and frequency for you. Before starting this medication, ensure you inform your doctor of any current health conditions or ongoing medications. If you experience any side effects, report them to your doctor immediately. It's crucial to continue taking the medicine for the full duration prescribed by your doctor for optimal results.

Nebider H 5/12.5 MG Tablet 10 is used for the following:

Management of high blood pressure in adults
Effective control of hypertension when either Nebivolol or Hydrochlorothiazide alone is insufficient
Achievement of better blood pressure regulation due to the combination of two antihypertensive agents with complementary mechanisms

Directions for Use of Nebider H 5/12.5 MG Tablet 10

Here are some instructions while taking Nebider H 5/12.5 MG Tablet 10:

Swallow this medicine whole with a sufficient amount of water.
Avoid breaking or chewing the tablet.
It's recommended to take your medicine at the same time each day to maintain a consistent level in your body.
Never take more than your doctor's recommended dose without consulting them first.
Ensure you do not stop taking this medicine without speaking to your doctor first.

Nebider H 5/12.5 MG Tablet 10 is taken orally.

Side Effects of Nebider H 5/12.5 MG Tablet 10

While using Nebider H 5/12.5 MG Tablet 10, you may experience some side effects. These include:

Headache
Dizziness
Fatigue
Nausea
Diarrhoea
Insomnia: This refers to difficulty in falling asleep or maintaining sleep.
Bradycardia: This term means a slower-than-normal heart rate.
Impotence: This is a condition in which a man can't achieve or maintain an erection during sexual performance.
Decreased libido: This means reduced interest in sexual activity.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Nebider H 5/12.5 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Nebider H 5/12.5 MG Tablet 10 with food or milk to lessen this effect.
Insomnia: If sleep disturbance occurs after taking this medicine, consider taking it early in the evening.

How Nebider H 5/12.5 MG Tablet 10 Works?

Nebider H 5/12.5 MG Tablet 10 essentially contains two active ingredients:

Hydrochlorothiazide (12.5 mg): This is a type of medicine known as a diuretic, which helps your kidneys eliminate extra water and salt from your body. By doing so, it reduces the volume of blood in your body and hence lowers blood pressure.
Nebivolol (5 mg): This is a highly selective beta-1 adrenergic receptor blocker which works by relaxing your blood vessels, slowing down your heart rate, and reducing the force with which your heart needs to pump blood around the body. This ultimately lowers your blood pressure. Additionally, nebivolol has properties that allow it to widen (or dilate) blood vessels, which further helps reduce blood pressure.

Pregnancy

Caution is advised while taking Nebider H 5/12.5 MG Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Before breastfeeding, ensure to discuss with your doctor the potential risks and benefits of using Nebider H 5/12.5 MG Tablet 10.

Alcohol

It's advisable to limit alcohol consumption while on this medicine, as it might enhance its side effects like dizziness or drowsiness.

Liver

Patients with severe liver impairment should use Nebider H 5/12.5 MG Tablet 10 with caution and under close medical supervision due to the risk of worsening their condition.

Kidney

If you have a history of kidney problems, caution is advised before using Nebider H 5/12.5 MG Tablet 10. It would be a good idea to consult your doctor before starting this medicine.

Using Machines & Driving

This medicine may cause dizziness or drowsiness. Avoid operating machinery or driving until you know how Nebider H 5/12.5 MG Tablet 10 affects you.

Allergy

Patients with a history of allergies, especially to sulfa medicines, should use this medicine with caution as hydrochlorothiazide is a sulfonamide derivative

Children

Nebider H 5/12.5 MG Tablet 10 is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Elderly patients should take Nebider H 5/12.5 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects, particularly if they have liver and kidney issues or are on other medication. Your doctor will guide you based on your health status.

Interactions of Nebider H 5/12.5 MG Tablet 10

Drug-Drug Interactions

Nebider H 5/12.5 MG Tablet 10 interacts with the following medicines:

Cardiac glycosides: Medicines like digoxin may interact with Nebider H 5/12.5 MG Tablet 10, possibly leading to altered effects or increased risk of side effects.
Non-steroidal Anti-Inflammatory Medicines (NSAIDs): Medicines like ibuprofen and naproxen can reduce the diuretic and blood pressure-lowering effects of this medicine when taken together.

Drug-Food Interactions

Certain food items may interact with Nebider H 5/12.5 MG Tablet 10:

High sodium foods: Consuming foods high in sodium might decrease the effectiveness of hydrochlorothiazide, an ingredient in Nebider H 5/12.5 MG Tablet 10.

Drug-Disease Interactions

Nebider H 5/12.5 MG Tablet 10 interacts with the following diseases:

Diabetes: This medicine could impact the control of blood sugar levels, making it necessary to closely monitor glucose levels when using this medication.
Bronchial asthma: Patients with a history of bronchial asthma should use this tablet cautiously as nebivolol, a component of Nebider H 5/12.5 MG Tablet 10, may worsen these conditions.

Daily Dose

Your daily dose of Nebider H 5/12.5 MG Tablet 10 should be as instructed by your doctor. The dosage might vary based on your health condition and how well you respond to the medicine. Always stick to the prescribed dosage and do not exceed it without discussing with your doctor.

Over Dose

If you accidentally take more than the recommended dose of Nebider H 5/12.5 MG Tablet 10, you might feel dizzy or nauseous. In such a case, drink plenty of water and inform your doctor about the situation.

Missed Dose

In case you forget to take a dose of Nebider H 5/12.5 MG Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Always talk to your doctor before making any changes in your dosage.

Store Nebider H 5/12.5 MG Tablet 10 at room temperature.
Keep the medicine in a dry place, shielded from light and moisture.
Always make sure it's out of reach of children.
Use the Tablet before its expiry date for maximum efficacy.

Consuming less salt can help manage high blood pressure, which is what Nebider H 5/12.5 MG Tablet 10 is used to manage.
Drinking plenty of water can help your kidneys function effectively and support the diuretic action of hydrochlorothiazide in the Tablet.

Fact Box

Drug Category	Beta-Blocker, Diuretic
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension

What is Nebider H 5/12.5 MG Tablet 10 used for?

Nebider H 5/12.5 MG Tablet 10 helps manage high blood pressure in adults when a single medicine isn't enough to control it effectively.

How does Nebider H 5/12.5 MG Tablet 10 work?

It combines two active ingredients: hydrochlorothiazide, which reduces blood volume by removing excess water and salt from the body, and nebivolol, which relaxes blood vessels and slows down heart rate.

When should I take Nebider H 5/12.5 MG Tablet 10?

You should take this medicine exactly as per your doctor's instructions.

Can Nebider H 5/12.5 MG Tablet 10 cause side effects?

Yes, it may cause side effects like headache, dizziness, fatigue, nausea, diarrhoea or decreased libido. Please consult your doctor if you experience any unusual symptoms.

Are there any precautions I need to take while using Nebider H 5/12.5 MG Tablet 10?

Yes, people with severe lung disease or liver or kidney impairment must use this medicine cautiously and under close medical supervision.

Can Nebider H 5/12.5 MG Tablet 10 interact with other medications?

Yes, it may interact with certain medicines like digoxin, lithium or non-steroidal anti-inflammatory drugs (NSAIDs). Always inform your doctor about all medications you're taking.

How should I store Nebider H 5/12.5 MG Tablet 10?

Store at room temperature in a dry place, away from light and moisture. Keep it out of reach of children and pets.

Last Updated On 02 Jan. 2025 | 12:58PM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

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Manufacturer details

3RD FLOOR, 301-302, KUNTHU COMMERCE CENTRE, BANGUR NAGAR, GOREGAON WEST, Mumbai Suburban, Maharashtra, 400090

Country of origin: INDIA

References

HYPOLOC PLUS. (n.d.). Package leaflet: Information for the user HYPOLOC PLUS 5 mg / 12.5 mg film-coated tablets Nebivolol / Hydrochlorothiazide. https://www.hpra.ie/img/uploaded/swedocuments/ad7d612b-caee-48be-863e-c716264fcb72.pdf
MICRO LABS LIMITED, INDIA. (n.d.). SUMMARY OF PRODUCT CHARACTERISTICS. https://rwandafda.gov.rw/wp-content/uploads/2024/01/NEBILONG-H-Nebivolol-5mg-and-Hydrochlorothiazide-12.5mg-Tablets-SmPC.pdf
USP. (n.d.). HCTZT:R2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/040735s004,040770s003lbl.pdf
Hydrochlorothiazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00999
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2007). [Prescribing information]. In BYSTOLIC (pp. 1–7). https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021742s022lbl.pdf
Nebivolol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04861

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