Gliclaglaze Mr 60 Tablet 15

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Composition

Gliclazide (60 Mg)

Gliclaglaze Mr 60 Tablet 15 is primarily used to manage blood sugar levels in adults suffering from type 2 diabetes mellitus. It is classified as an oral antidiabetic medication and falls under the sulfonylurea category of medicines.

This medicine plays a vital role when diet, exercise, and weight reduction alone are not enough to control blood glucose levels. It can be used on its own or in combination with other medicines, such as metformin, to achieve better glycemic control. However, it is not recommended for managing type 1 diabetes or diabetic ketoacidosis.

Before starting this medicine, you should consult your doctor about the appropriate dosage and frequency of use per day. Inform your doctor if you have any pre-existing conditions or if you are currently taking other medications. If you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking Gliclaglaze Mr 60 Tablet 15 for the duration prescribed by your doctor.

Gliclaglaze Mr 60 Tablet 15 is used for the following:

Management of type 2 diabetes mellitus in adults when dietary changes, physical exercise and weight reduction are not sufficient to control blood glucose levels.
Used alone as a primary treatment or in combination with metformin or other oral antidiabetic medicines.

Directions for Use of Gliclaglaze Mr 60 Tablet 15

Swallow the tablet whole with a full glass of water.
Avoid crushing, chewing or breaking the tablet.
Do not exceed the recommended dose of the medicine without consulting your doctor.
Ensure you take this medicine regularly at the same time each day for best results.
If you miss a dose, never try to compensate by taking a double dose. Instead, just carry on with your next scheduled dose.
Always consult your doctor for specific advice on how to best use this medicine.

Gliclaglaze Mr 60 Tablet 15 is taken orally.

Side Effects of Gliclaglaze Mr 60 Tablet 15

Gliclaglaze Mr 60 Tablet 15 may have the following common side effects:

Hypoglycaemia
Nausea
Vomiting
Diarrhoea
Dyspepsia: This refers to indigestion or an upset stomach

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gliclaglaze Mr 60 Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Diarrhoea: Consider taking Gliclaglaze Mr 60 Tablet 15 with food. Drink plenty of fluids to avoid dehydration.
Dyspepsia: To lessen indigestion, you can take this medicine after meals.

Gliclaglaze Mr 60 Tablet 15 contains gliclazide (60 mg), which works on the body as follows:

Increases Insulin Secretion: Gliclazide stimulates the beta-cells of the pancreas to release more insulin.
Reduces Blood Glucose Levels: The increased insulin secretion from the action of gliclazide aids in lowering blood glucose levels by promoting cellular uptake of glucose.
Increases Tissue Sensitivity to Insulin: In addition to stimulating insulin secretion, gliclazide may also help in increasing tissue sensitivity to insulin.
Inhibits Hepatic Gluconeogenesis: Gliclazide can possibly inhibit hepatic gluconeogenesis, which is the process of making glucose from non-carbohydrate sources in the liver.

Pregnancy

If you are pregnant or planning to conceive, Gliclaglaze Mr 60 Tablet 15 might not be the best option for you. This medicine may harm your unborn baby. It's crucial to discuss this with your doctor before starting this medication.

Breastfeeding

Gliclaglaze Mr 60 Tablet 15 is not recommended for breastfeeding women. This medicine can pass into breast milk and may harm your baby. Always consult with your doctor before starting any new medication while breastfeeding.

Alcohol

Drinking alcohol could enhance the blood sugar-lowering effect of Gliclaglaze Mr 60 Tablet 15, leading to an increased risk of hypoglycaemia (low blood sugar). It's best to minimise alcohol consumption while taking this medication.

Liver

If you have liver problems, using Gliclaglaze Mr 60 Tablet 15 may require special caution. This medicine could affect your liver function, particularly if you have severe liver disease. Make sure to discuss any liver-related concerns with your doctor before starting this treatment.

Kidney

For those with a history of kidney issues, caution is advised when taking Gliclaglaze Mr 60 Tablet 15. Your doctor will guide you based on your health status.

Using Machines & Driving

Hypoglycaemia (low blood sugar) can occur when taking Gliclaglaze Mr 60 Tablet 15 and could affect your ability to drive or operate machinery. If you experience symptoms like dizziness or confusion, refrain from these activities until you feel better.

Allergy

If you're allergic to gliclazide or other sulfonylureas, avoid using Gliclaglaze Mr 60 Tablet 15. An allergic reaction can cause symptoms like skin rashes, itching, or breathlessness. Share your allergic history with your doctor for better guidance.

Children

Gliclaglaze Mr 60 Tablet 15 is not recommended for children under the age of 18 as its safety and effectiveness have not been well-established in this age group.

Older Patients

Older patients should use Gliclaglaze Mr 60 Tablet 15 under medical supervision. You might be more susceptible to its side effects, especially hypoglycaemia. Your doctor will guide you based on your health status.

Interactions of Gliclaglaze Mr 60 Tablet 15

Drug-Drug Interactions

Gliclaglaze Mr 60 Tablet 15 interacts with the following medicines:

Other antidiabetic medicines: Glychek 60 D tablet may enhance the lowering blood sugar effect of other antidiabetic medicines like metformin, leading to a risk of low blood sugar levels.
ACE Inhibitors: Medicines such as lisinopril and ramipril could increase the glucose-lowering effect of Glychek 60 D tablet.
Corticosteroids: Medicines such as prednisone can diminish the glucose-lowering effect of Glychek 60 D tablet.
Thiazide Diuretics: Medicines like hydrochlorothiazide can reduce the blood sugar effect of Glychek 60 D tablet.
Oral Contraceptives: Birth control pills such as ethinylestradiol can decrease the glucose-lowering action of Glychek 60 D tablet.

Drug-Food Interactions

None

Drug-Disease Interactions

Gliclaglaze Mr 60 Tablet 15 interacts with the following diseases:

Malnourishment or Irregular dietary habits: These conditions may increase your risk for hypoglycemia (low blood sugar levels).
Adrenal/Pituitary insufficiency: These conditions can affect how your body responds to Glychek 60 D tablet, potentially impacting its efficacy.
Severe kidney or liver impairment: These conditions can impact how your body processes Glychek 60 D tablet, potentially leading to increased side effects.

Daily Dose

The daily dose of Gliclaglaze Mr 60 Tablet 15 should be taken as advised by your doctor. This dosage might vary based on factors like how severe your condition is and how you respond to the medicine. Always stick to the dosage recommended by your doctor, and don't exceed it without consulting them first.

Over Dose

If you have accidentally taken more Gliclaglaze Mr 60 Tablet 15 than recommended, you may experience symptoms like excessive sweating, tremors, and a rapid heartbeat. These signs are linked to low blood sugar or hypoglycaemia. If you notice these symptoms, inform your doctor promptly.

Missed Dose

If you forget to take your Gliclaglaze Mr 60 Tablet 15, this might disrupt your blood sugar control. If you realise you've missed a dose, take it as soon as you remember. But if it's nearly time for the next one, skip the missed dose and continue your regular schedule. Don't increase your dosage without discussing it with your doctor.

Store Gliclaglaze Mr 60 Tablet 15 at room temperature, ideally between 15-30°C.
Keep the medicine away from sources of light and moisture.
Ensure it is stored in a place out of reach of children.
Make certain to use the tablet before its expiry date.

Maintain a balanced diet low in sugar and high in fibre, as Gliclaglaze Mr 60 Tablet 15 is used to manage type 2 diabetes.
Regular physical exercise can also assist in managing type 2 diabetes. Try to do 30 minutes of exercise daily.

Fact Box

Drug Category	Insulin Secretagogue
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is the role of Gliclaglaze Mr 60 Tablet 15?

Gliclaglaze Mr 60 Tablet 15 manages type 2 diabetes by increasing the amount of insulin your body makes, which lowers your blood sugar levels.

How long does it take for Gliclaglaze Mr 60 Tablet 15 to start working?

The effect of Gliclaglaze Mr 60 Tablet 15 generally starts within 2-4 weeks. For optimal blood sugar control, it may take longer. In general, it depends on your health status and the severity of your condition.

Should I take Gliclaglaze Mr 60 Tablet 15 with food?

Yes, Glychek should be taken with breakfast, or as prescribed by the doctor. It's important not to crush, chew or break the tablet; swallow it whole.

What happens if I miss a dose of Gliclaglaze Mr 60 Tablet 15?

If you miss a dose, take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one.

Can I consume alcohol while taking Gliclaglaze Mr 60 Tablet 15?

Minimise your alcohol intake while on this medication, as it can increase the risk of low blood sugar and cause unpleasant reactions.

Can I use Gliclaglaze Mr 60 Tablet 15 during pregnancy or breastfeeding?

Consult your doctor before using Glychek during pregnancy or breastfeeding, as it may cause harm to the baby.

How should I store my Gliclaglaze Mr 60 Tablet 15?

Store your tablets at room temperature (15-30°C), away from light and moisture. Ensure they are kept out of reach of children.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

References

National Center for Biotechnology Information. (2018). A comparative study of glimepiride and gliclazide in combination with metformin in subjects with type 2 diabetes who are inadequately controlled with metformin alone: a randomized, double-blind, non-inferiority study. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894204/ on 1 April 2024.
U.S. Food and Drug Administration. (2013). Medical Review(s). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2013/204042Orig1s000MedR.pdf on 1 April 2024.
Gliclazide. (n.d.). Retrieved 13 June 2024, from https://go.drugbank.com/drugs/DB01120
Oral hypoglycemics overdose: Medlineplus medical encyclopedia. (n.d.). Retrieved 13 June 2024, from https://medlineplus.gov/ency/article/002588.htm
Gliclazide 60 mg modified-release tablet—Summary of Product Characteristics (Smpc)—(Emc). (n.d.). Retrieved 13 June 2024, from https://www.medicines.org.uk/emc/product/14497

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