Dvn Forte Tablet 10

Overseas Healthcare Pvt Ltd.

Strip of 10 Units

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MRP ~~₹173.50~~

₹142.27

₹17.35/Units

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Composition

Drotaverine (80 Mg) + Paracetamol/acetaminophen (500 Mg)

Dvn Forte Tablet is primarily used to treat various stomach and intestinal issues, such as peptic ulcers, gastritis, excess stomach acid, diarrhoea caused by functional issues, irritable bowel syndrome (IBS), and stomach or intestinal spasms. It is a combination medicine belonging to the class of medications known as antispasmodic agents and non-steroidal anti-inflammatory drugs (NSAIDs).

It is also helpful in managing bile duct disorders like biliary dyskinesia and chronic gallstones. Additionally, it can be used to relieve spasms in the urinary and genital systems.

Before starting this medicine, inform your doctor about any pre-existing conditions or ongoing medications you are taking. If you notice any side effects while on this medicine, consult your doctor immediately. It is important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Dvn Forte Tablet is used to manage the following conditions:

Abdominal pain, cramps, and spasms
IBS (a disorder causing abdominal pain and changes in bowel habits)
Biliary colic and spasms caused by gallstones
Bile duct disorders like biliary dyskinesia and chronic gallstones

Directions for Use of Dvn Forte Tablet 10

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Take the medicine with or after meals to minimise potential stomach discomfort.
Always take the medicine in the dosage and frequency prescribed by your doctor.
If you decide to stop taking this medicine, consult your doctor first.

Dvn Forte Tablet is taken orally.

Dvn Forte Tablet may have the following common side effects:

Nausea and vomiting
Diarrhoea
Constipation
Abdominal discomfort
Indigestion
Bloating or flatulence
Headache
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Dvn Forte Tablet with food or milk to lessen this effect.
Dizziness: Consider taking this medicine at night if it causes dizziness during the day.

Dvn Forte Tablet works in the human body in the following ways:

Drotaverine (80 mg): This ingredient selectively inhibits the phosphodiesterase 4 (PDE4) enzyme. This enzyme is responsible for the degradation of cyclic adenosine monophosphate (cAMP), a compound found inside cells. By inhibiting the PDE4 enzyme, drotaverine increases cAMP levels, leading to the relaxation of smooth muscles in the gut and other internal organs, helping relieve cramps, spasms, and colic.
Paracetamol (500 mg): Paracetamol works by inhibiting the cyclooxygenase (COX) enzyme, responsible for producing prostaglandins (chemical substances that cause pain, inflammation, and fever). By blocking prostaglandin synthesis, paracetamol provides pain relief.

Pregnancy

Dvn Forte Tablet is not recommended to be used in pregnancy as it may cause potential harm to the foetus. If you are pregnant or planning to conceive, it is crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

This medicine is contraindicated while breastfeeding as the components of the medicine are secreted in breast milk, which may cause adverse effects in nursing infants. Always consult your doctor before taking this medicine if you are breastfeeding.

Alcohol

Avoid alcohol consumption while on this medication, as it can increase the risk of stomach infection and other side effects. Always consult your doctor regarding alcohol intake.

Liver

Caution is advised while taking this medicine if you have any liver problems. This medicine may affect liver function, so discuss your condition with your doctor before starting this medication.

Kidney

This medicine is contraindicated in patients with severe kidney disease or kidney impairment, as it could lead to nephrotoxicity (kidney damage). Always consult your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause dizziness or sleepiness in some individuals. If you feel dizzy or unwell after taking this medicine, avoid activities such as driving or operating heavy machinery.

Allergy

Dvn Forte Tablet is contraindicated if you are allergic to drotaverine or paracetamol. Always discuss your allergies with your doctor.

Children

This medicine is not recommended for paediatric use without a doctor's advice. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients, especially those with liver or kidney issues, should take this medicine under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Dvn Forte Tablet may interact with the following medications:

Anticoagulants: Medicines like warfarin and heparin may interact with Dvn Forte Tablet, increasing the risk of bleeding.
Cholesterol-Lowering Medications (Cholestyramine): Cholestyramine can reduce the absorption of paracetamol from the digestive tract. This may decrease the effectiveness of this tablet, requiring careful timing between doses (e.g., a gap of 1-2 hours).
Prokinetic Agents (Metoclopramide and Domperidone): Metoclopramide and domperidone, which enhance stomach emptying, may increase the absorption rate of paracetamol. This can lead to faster onset of action but may also increase the risk of side effects if not monitored.
Anticonvulsants (Carbamazepine): Carbamazepine may enhance the metabolism of paracetamol in the liver, potentially reducing its effectiveness. Additionally, prolonged use can increase the risk of liver toxicity, especially with high doses of paracetamol.
Muscarinic Antagonists (Atropine): Atropine may reduce the efficacy of drotaverine by counteracting its smooth muscle-relaxing effects. This can make the treatment of spasms less effective.
Antiparkinson Agents (Levodopa): Drotaverine can reduce the effectiveness of levodopa by interfering with its muscle-relaxing benefits. Patients using both medications may experience worsening Parkinson’s symptoms, such as tremors or rigidity.
Antidepressants (Diazepam): Diazepam may enhance the sedative effects of drotaverine, leading to increased drowsiness or lethargy. Caution is advised when using these medications together, especially in activities requiring focus.
Antibiotics (Flucloxacillin): Flucloxacillin, a penicillin-class antibiotic, does not directly interact with this tablet but may increase the risk of liver toxicity when combined with high doses of paracetamol. Patients with liver concerns should consult their doctor before combining these medications.

Drug-Food Interactions

There are no specific food items that interact significantly with Dvn Forte Tablet.

Drug-Disease Interactions

Dvn Forte Tablet may interact with the following diseases:

Cardiovascular diseases: Patients with cardiovascular diseases like myocardial infarction (heart attack) or stroke are also contraindicated from using this medicine as it may worsen their condition.
Kidney disease: Patients with severe kidney impairment are also contraindicated from using this medicine as it could potentially worsen their condition.

Daily Dose

The daily dose of Dvn Forte Tablet should be taken as per your doctor's instructions. Your dosage may vary depending on factors such as the severity of your condition and how you respond to the medicine.

Over Dose

If you accidentally take more than the recommended dosage, you might experience common side effects such as nausea, vomiting, or diarrhoea. If these symptoms persist or worsen, do inform your doctor.

Missed Dose

If you missed a dose of the medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Dvn Forte Tablet at room temperature below 30°C.
Keep it away from excess heat, light, and moisture.
Always ensure the tablet container is tightly closed.
Remember to keep this medicine out of the reach of children.
Use the medicine before the expiry date mentioned on the pack.

For conditions like IBS, try including more fibre in your diet. This can help manage symptoms by making your bowel movements more regular.
If you are dealing with painful menstruation or dysmenorrhoea, moderate exercise such as walking or yoga may help reduce pain.

Fact Box

Drug Category	Antispasmodic, NSAIDs
Therapeutic Category	Anti-inflammatory, Pain Reliever
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Dysmenorrhoea, IBS, Renal Colic

What is Dvn Forte Tablet used for?

Dvn Forte Tablet is used for managing abdominal pain, cramps, and spasms associated with conditions like IBS and dysmenorrhoea.

How does Dvn Forte Tablet work?

This medicine works by combining the muscle-relaxing effects of drotaverine with the pain-relieving and anti-inflammatory properties of paracetamol. Together, these components help manage abdominal discomfort.

Can Dvn Forte Tablet be taken with food?

Yes, it is recommended that you take this medicine with food or after your meals. This can help reduce possible side effects, such as stomach pain and discomfort.

What are some common side effects of Dvn Forte Tablet?

Some common side effects of the medicine may include nausea, vomiting, diarrhoea, abdominal discomfort, dizziness, and headache. If these symptoms persist, inform your doctor.

Can Dvn Forte Tablet be used during pregnancy or breastfeeding?

Dvn Forte Tablet is contraindicated in pregnancy and breastfeeding due to potential risks to the baby. Always consult your doctor before starting this medicine.

Is long-term use of Dvn Forte Tablet safe?

No, long-term use of this medicine is not recommended due to potential gastrointestinal, cardiovascular, and renal complications associated with paracetamol, an NSAID. Always consult your doctor for guidance.

What should I do if I miss a dose of Dvn Forte Tablet?

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Last Updated On 15 Jan. 2025 | 11:22AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Kanakia Wall Street- B Wing, 1109, 11th Floor, Andheri - Kurla Rd, Andheri East, Maharashtra 400093

Country of origin: INDIA

References

Clarification -20 tbl and 24 tbl per pack -OTC medicine 100 tbl per packprescription medicine. (n.d.). Ravimiregister.Ee. Retrieved jan 3, 2025 from https://www.ravimiregister.ee/Data/PIL_ENG/PIL_11232_ENG.pdf
PubChem. (n.d.). Drotaverine. Nih.Gov. Retrieved jan 3, 2025 from https://pubchem.ncbi.nlm.nih.gov/compound/1712095
PubChem. (n.d.-e). Drotaverine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Drotaverine
Drotaverine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06751
Efficacy and Safety of Drotaverine Hydrochloride in Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Study. (2014, November). ncbi.nlm.nih.gov. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271014/

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