Venlafaxine
Uses of Venlafaxine
Primarily, Venlafaxine is used for the management of major depressive disorder (MDD), generalised anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder. It is part of the serotonin-norepinephrine reuptake inhibitors (SNRIs) class of medications.
In some cases, Venlafaxine might also be prescribed for managing diabetic neuropathy, menopausal hot flashes and attention deficit hyperactivity disorder (ADHD).
Side effects of Venlafaxine
Nausea
Drowsiness
Dizziness
Dry mouth
Insomnia
How Venlafaxine works
Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI).
It works by increasing the levels of serotonin and norepinephrine in the brain. Serotonin and norepinephrine are neurotransmitters, which are chemicals that transmit signals between nerve cells. Venlafaxine inhibits or prevents these neurotransmitters from being reabsorbed back into the nerve cells in the brain. This leaves more of these chemicals available in the brain, helping to improve mood and reduce feelings of depression and anxiety.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Venlafaxine is available for use via the oral route (immediate-release tablets and extended-release capsules).
Age and Dose Restrictions
This medicine is intended for use in adults only.
Contraindications
Venlafaxine is contraindicated in individuals known to be allergic to Venlafaxine or any of its components. It is also contraindicated in patients who have taken monoamine oxidase inhibitors (MAOIs) within the past 14 days.
Other Medications to Avoid
This medicine can interact with MAOIs (such as phenelzine and selegiline), other antidepressants (like fluoxetine, and paroxetine), and blood thinners (such as warfarin).
Overdose and Missed Dose
An overdose of Venlafaxine may result in symptoms like extreme drowsiness, vertigo, tachycardia, seizures, or even coma. If you suspect an overdose, seek urgent medical attention.
If you forget to take your dose of Venlafaxine, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one. Never take two doses at once.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If you are experiencing nausea or vomiting, try taking this medicine with food.
Drink plenty of water to manage dry mouth.
Try to rest and relax if you are experiencing dizziness or fatigue.
Use in Driving and Operating Machinery
Venlafaxine may affect your ability to drive or operate heavy machinery, as it can cause drowsiness and dizziness. Avoid these activities until you know how this medicine affects you.
Use in Pregnancy and Lactation
It is advised to consult your doctor before taking this medicine if you are pregnant or breastfeeding.
Caution in Other Conditions
Patients with liver or kidney conditions should exercise caution when taking Venlafaxine. Also, individuals with high blood pressure or heart disease should be careful, as this medicine can cause an increase in blood pressure.
Special Dietary and Lifestyle Recommendations
Limit your intake of caffeine, as these can worsen anxiety and may also interact with Venlafaxine.
Frequently asked questions
Can Venlafaxine cause sleep disturbances?
Yes, Venlafaxine can cause sleep disturbances such as insomnia as one of its side effects. If you experience difficulties falling or staying asleep, consult your doctor.
Will taking Venlafaxine affect my fertility?
There is no concrete evidence to suggest that Venlafaxine directly affects fertility. However, if you are planning to conceive, it is advisable to discuss this with your doctor.
Is it safe to take Venlafaxine daily?
Yes, it is safe to take Venlafaxine daily if prescribed by your doctor. It is important not to exceed the recommended dose.
How much time does Venlafaxine take to work?
Venlafaxine may take about 2-4 weeks to start showing noticeable improvements in mood and symptoms. Complete effects may be seen after 6–8 weeks of treatment.
Is Venlafaxine available over the counter, or do I need a prescription?
Venlafaxine requires a prescription and is not available over the counter due to its potential for side effects and interactions with other medications.
Is Venlafaxine a steroid?
No, Venlafaxine is not a steroid.
What is the best time to take Venlafaxine?
The best time to take Venlafaxine should be as advised by your doctor.
Venlafaxine in other salts
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