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Clotrimazole + Tinidazole

Uses of Clotrimazole + Tinidazole

  • The primary use of Clotrimazole + Tinidazole lies in managing bacterial vaginosis, vulvovaginal candidiasis and trichomoniasis. It falls under the group of antifungal and antibiotic medications.

Side effects of Clotrimazole + Tinidazole

  • Vaginal burning, itching, or irritation

  • Headache

  • Nausea or upset stomach

  • Metallic taste in the mouth

  • Diarrhoea

How Clotrimazole + Tinidazole works

  • Clotrimazole is an antifungal agent. It disrupts the cell membrane of fungi by inhibiting the synthesis of ergosterol, an important component of the fungal cell membrane. This action causes the death of the fungal cells, thereby eliminating the infection.

  • Tinidazole is an antibiotic and antiprotozoal medication. It gains access into the bacterial or parasitic cells where it is reduced by cellular enzymes to form unstable molecules known as free radicals. These radicals cause damage to the DNA of these organisms which subsequently results in their death and eradication of the infection. Working together, Clotrimazole and Tinidazole effectively manage various types of vaginal infections caused by bacteria, fungi, and certain parasites.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer|

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 Years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Clotrimazole + Tinidazole is available for use via vaginal route in the form of cream and tablet (usually inserted into the vagina using an applicator), composition suppositories.

Age and Dose Restrictions

  • This combination medication is intended for use in adults aged 18 and above.

  • Use in children is generally not recommended without medical advice.

Contraindications

  • The use of Clotrimazole + Tinidazole is contraindicated in patients with known hypersensitivity to either clotrimazole or tinidazole.

  • It is also contraindicated in patients with a history of hypersensitivity to other azole antifungals or nitroimidazole antibiotics.

Other Medications to Avoid

  • This combination may interact with anticoagulants (such as warfarin), immunosuppressants (like cyclosporine and tacrolimus), anti-seizure medications (including phenytoin), and antacid (like cimetidine).

Overdose and Missed Dose

  • An overdose may cause severe nausea, vomiting, stomach pain, an irregular heartbeat, and seizures. If you suspect an overdose, contact a healthcare professional immediately.

  • If you forget a dose of this medicine, use it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Resting or sleeping in a dark, quiet room can help alleviate headaches.

  • Avoiding spicy or fatty foods may help manage an upset stomach or diarrhoea.

Use in Driving and Operating Machinery

  • Clotrimazole + Tinidazole may cause dizziness or sleepiness. If you experience these side effects, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • The use of Clotrimazole + Tinidazole during pregnancy or lactation should only be done under the advice and supervision of a doctor.

Caution in Other Conditions

  • Patients with liver disease should exercise caution when using Clotrimazole + Tinidazole as it can cause liver damage. Regular monitoring of liver function may be necessary.

  • Caution is advised in patients with blood disorders as this medication can cause a decrease in white blood cells, leading to a higher risk of infections.

Special Dietary and Lifestyle Recommendations

  • Maintain good hygiene to prevent the recurrence of vaginal infections.

  • Wear cotton underwear and avoid tight-fitting pants or jeans to allow air circulation.

  • Avoid using scented soaps, lotions, or other products in the vaginal area that can disrupt the natural balance of bacteria and fungi.

Frequently asked questions

No, Clotrimazole + Tinidazole is not a steroid. It is an antifungal and antibiotic combination used for treating various vaginal infections.

Clotrimazole + Tinidazole is not associated with any effects on sleep. However, if you experience sleep disturbances while using it, please consult your doctor.

Clotrimazole + Tinidazole is not typically associated with any effects on fertility. However, if you are planning to conceive or facing any fertility issues, please discuss with your doctor.

Yes, it is generally safe to use Clotrimazole + Tinidazole daily, for the duration that your doctor has prescribed.

The medicine starts working soon after application; however, it may take a few days before significant improvement is observed in the infection.

The best time to apply Clotrimazole + Tinidazole is as your doctor advises. Please follow your doctor's instructions regarding dosage timings.

The vegan status of Clotrimazole + Tinidazole would depend on the specific formulation and manufacturing process. If this concerns you, discuss it with your doctor or pharmacist.

Terms & Conditions


Available medicines for CLOTRIMAZOLE + TINIDAZOLE
Costrim V 200/500 MG Tablet 4
Costrim V 200/500 MG Tablet 4
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Infa Vt Ointment 45gm
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Clodaz V6 Tablet Vt 6
Clodaz V6 Tablet Vt 6
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Pack of 6 Units
₹40.92
MRP ₹49.90
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