Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B
Uses of Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B
The main use of Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B is to manage bacterial eye infections. It belongs to the group of antibiotic and corticosteroid medicines.
Besides this, it also manages inflammation of the conjunctiva and cornea (bacterial conjunctivitis and keratitis).
Side effects of Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B
Burning sensation in the eyes
Stinging sensation
Irritation
Itching
Redness
Blurred vision
How Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B works
Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B is a combination used to treat eye infections.
Chloramphenicol is an antibiotic. It works by stopping the growth of bacteria by inhibiting their protein synthesis, which is a crucial process for bacteria to grow and reproduce.
Dexamethasone is a corticosteroid. It reduces inflammation by decreasing the body's immune response, thereby reducing swelling, redness, and pain in the affected area.
Phenylmercuric Nitrate is a preservative used in this medication. It does not contribute directly to managing the infection but helps to maintain the potency and stability of the other components in the medicine.
Polymyxin B is another antibiotic included in this combination. It works by disrupting the bacterial cell membranes, leading to cell death.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B combination is available for use via the ophthalmic route, in the form of an eye drop solution.
Age and Dose Restrictions
This medicine is meant for adults and children above 2 years of age.
Contraindications
This medicine combination is contraindicated in patients with known allergies to any of the components, including Chloramphenicol, Dexamethasone, Phenylmercuric Nitrate, or Polymyxin B.
It is also contraindicated in patients with viral or fungal eye infections, mycobacterial eye infections like tuberculosis, narrow-angle glaucoma, and corneal epithelial damage or defects.
Other Medications to Avoid
This combination may may interact with several medications, including other antibiotic eye drops (such as tobramycin or ciprofloxacin), additional corticosteroid eye drops (like prednisolone), and ocular decongestants (such as naphazoline).
Overdose and Missed Dose
In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
If you forget a dose of this medicine, apply it as soon as you remember. However, if it's nearly time for the next dose, skip the missed dose and continue with your regular schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage minor irritation or discomfort after applying the eye drops, try gently closing your eyes and resting for a few moments.
Drinking plenty of water can help manage any feelings of dryness or discomfort.
Use in Driving and Operating Machinery
This medication may blur your vision temporarily. Avoid driving, using machines, or doing anything that needs clear vision until you can see clearly.
Use in Pregnancy and Lactation
The use of this medicine during pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or child. Always consult your doctor before use.
Caution in Other Conditions
Patients with other eye conditions or eye injuries should use this medication with caution. Always discuss your medical history with your doctor before starting this medication.
Special Dietary and Lifestyle Recommendations
Maintain good eye hygiene to help prevent bacterial eye infections.
Try to avoid touching your eyes with unclean hands.
Do not share personal items like towels or makeup to prevent the spread of infection.
Frequently asked questions
Is Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B a steroid?
No, Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B is not entirely a steroid. It is a combination medicine with antibiotics (Chloramphenicol and Polymyxin B), a corticosteroid (Dexamethasone), and a preservative (Phenylmercuric Nitrate).
Is it safe to wear contact lenses while using Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B?
No, it is recommended to remove contact lenses before application. The lenses may be reinserted a few minutes after the application of the medication.
Can Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B cause discoloration in the eyes?
Yes, the preservative Phenylmercuric Nitrate in this medicine may cause a reversible grey-brown discolouration of the eye.
Is Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B addictive?
No, this medicine is not known to cause addiction or dependency.
If I have allergies, can I use Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B?
If you have known hypersensitivity to any component of this medicine, you should not use it. Always consult your doctor before starting any new medication.
Can Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B cause ocular hypertension?
Yes, this medicine may cause temporary ocular hypertension, especially with prolonged use.
What precautions should I take while using Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B?
While using Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B, it is crucial to avoid touching the dropper tip to any surface as it may contaminate the solution. Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi. In some individuals, intraocular pressure may become elevated if the medication is used for 10 days or longer.
Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate + Polymyxin B in other salts
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