Xafinact 100 Mg Tablet 10

Xafinact 100 Tablet 10

Sun Pharmaceutical Industries Ltd

Strip of 10 Units

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MRP ~~₹248~~

₹203.36

₹24.80/Units

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Composition

Safinamide (100 Mg)

Strength:

100 MG 50 MG

Xafinact 100 Tablet is primarily used as an add-on therapy to manage Parkinson's disease symptoms in adults. This medicine is part of a group known as monoamine oxidase type B (MAO-B) inhibitors.

Aside from the primary use, this tablet helps manage "off" episodes often experienced by Parkinson's patients. In these periods, the standard medication loses its effectiveness, leading to heightened symptoms such as difficulty moving and tremors. The usage of this tablet aids in increasing dopamine levels, which enhances motor function and reduces "off" time.

Before you commence taking this tablet, consult your doctor about the correct dosage and frequency for you. It's crucial that your doctor is aware of any existing conditions or ongoing medications you're taking before starting this medication. If you observe any adverse reactions while on this medicine, inform your doctor immediately and continue to take it for the period prescribed by your doctor for optimal results.

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Xafinact 100 Tablet is commonly used for the following health conditions:

Management of Parkinson's disease symptoms in adults
Reduction of "off" episodes in Parkinson's disease patients: "Off" episodes refer to periods when the patient's medications are not working well, leading to an increase in Parkinson's symptoms.
Improvement of motor function: This includes better control over movements and coordination.
Enhancement of daily life quality for Parkinson's disease patients by reducing stiffness and shaking.

Directions for Use of Xafinact 100 Tablet 10

Here are some general guidelines on how to take Xafinact 100 Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet as this can affect how the medicine works.
You can take this medicine with or without food, as per your preference.
Try to take your dose at the same time each day for consistent results.
Always consult your doctor if you have any questions or concerns about how to take this medicine.

Xafinact 100 Tablet is taken orally.

Taking Xafinact 100 Tablet may lead to some common side effects, which include:

Uncontrolled, involuntary movements
Falls
Nausea
Insomnia
Feeling dizzy

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Xafinact 100 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips for managing common side effects:

Uncontrolled, involuntary movements: If you observe uncontrolled movements after taking the medicine, consider adjusting your medication timing to bedtime.
Dizziness: To manage dizziness when standing up, try taking the medicine after meals to lessen this effect.

Xafinact 100 Tablet contains safinamide (100 mg), which acts on your body in the following ways:

Blocks MAO-B Enzyme: Safinamide works by inhibiting an enzyme called monoamine oxidase type B (MAO-B) in your brain. This enzyme is typically involved in breaking down dopamine.
Increases Dopamine Levels: By blocking MAO-B, safinamide effectively enhances dopamine levels in the brain. This increased presence of dopamine helps to manage Parkinson's symptoms.
Modulates Glutamate Release: In addition to inhibiting MAO-B, safinamide also modulates the release of a neurotransmitter named glutamate, which plays a role in Parkinson's disease, contributing further to its therapeutic benefits.

Pregnancy

Caution is advised while taking Xafinact 100 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Breastfeeding while taking Xafinact 100 Tablet is not recommended. It is important to discuss this with your doctor to understand the potential risks and benefits.

Alcohol

t's always a good idea to consult your doctor about this as alcohol may reduce this medicine's efficacy.

Liver

Xafinact 100 Tablet is contraindicated if you have severe liver impairment. If you have any liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before using Xafinact 100 Tablet if you have any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

As Xafinact 100 Tablet may cause drowsiness or dizziness, caution is advised while driving or operating machinery until you know how it affects you.

Allergy

If you are allergic to safinamide or any of the other ingredients in Xafinact 100 Tablet, avoid using this medicine. Consult your doctor for alternatives.

Children

Xafinact 100 Tablet is not recommended for use in children under 18 years of age as its safety and efficacy have not been established in this age group.

Older Patients

Older patients should take Xafinact 100 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised especially if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Xafinact 100 Tablet interacts with the following medicines:

Monoamine Oxidase Inhibitors (MAOIs): These can increase the risk of high blood pressure when taken with Xafinact 100 Tablet. Specific medications include isocarboxazid and phenelzine.
SSRIs, SNRIs, TCAs: Antidepressants like fluoxetine or venlafaxine can interact with Xafinact 100 Tablet, potentially leading to a condition known as serotonin syndrome.
Opioid pain medications: Medicines such as tramadol or methadone may increase the risk of serotonin syndrome when used with this medicine.

Drug-Food Interactions

No specific food interactions have been noted with Xafinact 100 Tablet. However, it's always best to follow your doctor's advice regarding diet while taking any medication.

Drug-Disease Interactions

Xafinact 100 Tablet interacts with the following diseases:

High Blood Pressure: The medication could increase blood pressure levels, so people with hypertension should monitor their blood pressure regularly while on this medication.
Mental Health Disorders: Patients with disorders like schizophrenia, bipolar disorder, or depression should be careful while using this medicine as it might worsen their symptoms.

Daily Dose

You should take the daily dose of Xafinact 100 Tablet as directed by your doctor. The amount you need might vary, depending on factors like how severe your condition is and how you respond to the medication. Always stick to the dosage advised by your doctor and don't exceed it without getting their approval first.

Over Dose

If you accidentally take more than the recommended dose of Xafinact 100 Tablet, you might experience symptoms such as agitation, confusion, hallucinations, sleepiness, and unusual movements. If this happens, get in touch with your doctor for advice.

Missed Dose

If you forget to take your Xafinact 100 Tablet at the usual time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and go back to your normal schedule. Don't double up on doses - if you're unsure what to do, consult your doctor.

Store Xafinact 100 Tablet at room temperature between 20°C to 25°C.
Keep the medicine in its original packaging to protect from moisture.
Ensure that the place of storage is out of sight and beyond the reach of children.
Check the expiry date on the package before use and do not consume if it has passed.

Engage in regular physical activity such as walking or stretching exercises, tailored to your capabilities, to help manage Parkinson's disease symptoms effectively.
Follow a balanced diet rich in antioxidants like fruits, vegetables, and whole grains which can help support brain health and potentially slow down the progression of Parkinson's disease. Always consult your doctor for personalised advice.

Fact Box

Drug Category	MAO-B Inhibitor
Therapeutic Category	Anti-Parkinsonian
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Parkinson's Disease, "Off" Episodes

What is Xafinact 100 Tablet used for?

Xafinact 100 Tablet is used to manage symptoms of Parkinson's disease, like shaking and difficulty moving, in adults experiencing "off" episodes.

How does Xafinact 100 Tablet work?

This medicine contains safinamide which increases dopamine levels in your brain, aiding motor function, and reducing Parkinson's symptoms during "off" episodes.

Can I take Xafinact 100 Tablet with food?

Yes, you can take Xafinact 100 Tablet with or without food. It should be swallowed whole with water for best results.

What are some common side effects of Xafinact 100 Tablet?

Common side effects may include uncontrolled movements, falls, nausea, insomnia, and dizziness when standing up. Consult your doctor if these persist.

Are there any precautions I should take while using Xafinact 100 Tablet?

Inform your doctor if you have liver problems, high blood pressure, mental health issues, sleep disorders, or a history of compulsive behaviours before starting this medicine.

Can Xafinact 100 Tablet interact with other medications?

Yes, it can interact with many medicines like MAO inhibitors, antidepressants and cold and cough medicines. Always inform your doctor about all the medicines you're currently taking.

How should I store Xafinact 100 Tablet?

Store it at room temperature between 20°C to 25°C. Keep the bottle tightly closed to protect from moisture and keep it out of reach of children.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

US WorldMeds, LLC, Inc. (2017). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207145lbl.pdf
DailyMed - XADAGO- safinamide mesylate tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c4d65f28-983f-42b4-bb23-023ae0fe81b2
Safinamide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06654
Safinamide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a617025.html

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