Zoledronic Acid
Uses of Zoledronic Acid
The primary use of Zoledronic Acid is to manage various bone disorders. It belongs to the bisphosphonate class of medicines.
Some secondary uses include the management of hypercalcemia of malignancy (high blood calcium levels due to cancer), prevention of skeletal-related events in patients with bone metastases from solid tumours and multiple myeloma, and treatment of Paget's disease of bone.
Side effects of Zoledronic Acid
Fever
Flu-like symptoms
Nausea
Vomiting
Diarrhoea
How Zoledronic Acid works
Zoledronic Acid is a bisphosphonate class medicine. It operates by binding to the bone tissue and inhibiting the action of osteoclasts, which are cells responsible for breaking down bone tissue.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Zoledronic Acid is administered intravenously (injection).
Age and Dose Restrictions
Zoledronic Acid is typically intended for use in adults. Children and adolescents may require different dosages or may not be suitable candidates for this medication, and thus the usage of Zoledronic Acid should be under the supervision of a doctor.
Contraindications
Zoledronic Acid is contraindicated in patients with hypersensitivity to Zoledronic Acid or any components of the formulation.
It is also contraindicated in individuals suffering from hypocalcemia or abnormally low levels of calcium in the blood.
Other Medications to Avoid
Zoledronic Acid can interact with aminoglycosides (such as gentamicin and amikacin), loop diuretics (such as furosemide and bumetanide) and nephrotoxic medications (such as cisplatin and cyclosporine).
Overdose and Missed Dose
In the case of an overdose of Zoledronic Acid, it's essential to seek immediate medical attention. Overdosing can lead to severe side effects such as kidney impairment, electrolyte imbalance, and bone pain.
If you miss a dose, administer it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses to compensate for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For nausea or vomiting, try taking the medicine with food or milk and drink plenty of water.
For flu-like symptoms, rest and hydration may help to alleviate these symptoms.
Use in Driving and Operating Machinery
Zoledronic Acid may cause dizziness or visual disturbances. As such, it may affect your ability to drive or operate machinery. If you do experience such side effects, avoid such activities until you are sure of how this medicine affects you.
Use in Pregnancy and Lactation
Zoledronic Acid should be used during pregnancy and breastfeeding only if the potential benefit justifies the potential risk to the foetus or infant. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Caution in Other Conditions
Patients with renal impairment should exercise caution when administering Zoledronic Acid as it can potentially worsen kidney function. Regular monitoring of kidney function is recommended in these patients.
Special Dietary and Lifestyle Recommendations
Make sure to maintain a diet rich in calcium and vitamin D as they are crucial for bone health.
Regular weight-bearing exercise can help to increase bone strength.
Frequently asked questions
What category of medicine is Zoledronic Acid?
Zoledronic Acid is not a steroid. It is a medication that belongs to the bisphosphonate class, specifically used for managing various bone disorders.
Can Zoledronic Acid impact my sleep?
Zoledronic Acid is not typically associated with direct effects on sleep. However, some people may experience side effects like fatigue, fever, or muscle pain after infusion, which could indirectly affect sleep. If you notice sleep disturbances, consult your healthcare provider.
Will administering Zoledronic Acid affect my fertility?
Zoledronic Acid can cause harm to the foetus and is therefore not recommended for use in pregnant women or women planning to conceive. Women of reproductive age should use effective contraception during and after treatment with Zoledronic Acid.
Is it safe to administer Zoledronic Acid daily?
The frequency of administering Zoledronic Acid depends on the condition being managed and your doctor's prescription. It is typically not administered daily.
How long does Zoledronic Acid take to show its effect?
The time taken for Zoledronic Acid to show its effect can vary based on the condition being managed and individual patient factors. Your doctor can provide more accurate information based on your specific situation.
Do I need a prescription to get Zoledronic Acid or is it available over the counter?
Zoledronic Acid is typically not available over the counter and usually requires a prescription from a doctor.
Is there any specific monitoring required while on Zoledronic Acid therapy?
Yes, regular kidney function monitoring is essential while on Zoledronic Acid therapy due to its potential for renal toxicity. Also, maintaining good oral hygiene and regular dental check-ups are crucial to prevent osteonecrosis of the jaw.
Subscribe
Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.
Download Truemeds
Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Contact Us
Our customer representative team is available 7 days a week from 9 am - 9 pm.
v3.3.6
2024 - Truemeds | All rights reservedOur Payment Partners
