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Vinorelbine

Uses of Vinorelbine

  • Vinorelbine's primary use lies in managing advanced or metastatic non-small cell lung cancer (NSCLC). It belongs to the vinca alkaloid family of chemotherapy medications.

  • In addition, it may also be used in the management of advanced breast cancer.

Side effects of Vinorelbine

  • Nausea and vomiting

  • Diarrhoea or constipation

  • Fatigue and weakness

  • Hair loss

  • Numbness or tingling in hands and feet

How Vinorelbine works

  • Vinorelbine is a chemotherapy medication.

  • It works by inhibiting microtubule formation during cell division. It binds to tubulin, preventing the proper assembly of microtubules, which disrupts mitosis and inhibits cancer cell proliferation. This mechanism makes it effective in treating various types of cancers, including lung and breast cancer.

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Written By

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Dr. Michelle FrankMedical Content Writer| 8 Years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Vinorelbine is available as an injectable solution.

  • It is administered intravenously by a healthcare professional.

Age and Dose Restrictions

  • This medicine is primarily meant for adults.

  • The specific dosage varies according to the type of cancer being managed and the patient's overall health and response to therapy.

Contraindications

  • This medicine is contraindicated for patients with known hypersensitivity to Vinorelbine or any of its components.

  • It should not be given to patients with severe bone marrow suppression.

Other Medications to Avoid

  • Vinorelbine may interact with several medications, including antifungal medicines like ketoconazole, antibiotics such as erythromycin, and anticonvulsants like phenytoin. It can also interact with anticancer agents such as cisplatin or doxorubicin, calcium channel blockers like diltiazem, and immunosuppressants such as cyclosporine.

Overdose and Missed Dose

  • If you suspect an overdose of Vinorelbine, contact your healthcare provider immediately. An overdose may cause severe side effects like bone marrow suppression leading to infections, bleeding or fatigue.

  • If you miss a dose, contact your doctor right away for instructions. Do not double up on the next dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To reduce nausea and vomiting, try taking small frequent meals. Drink plenty of fluids to prevent dehydration.

  • Try resting more if you experience fatigue or weakness.

  • Proper oral hygiene can help manage mouth sores.

Use in Driving and Operating Machinery

  • Vinorelbine may cause fatigue and weakness which can affect your ability to drive or operate machinery.

  • Avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

  • It is not recommended to use Vinorelbine during pregnancy as it may cause harm to the developing baby.

  • Breastfeeding mothers should also avoid this medicine as it may pass into breast milk.

Caution in Other Conditions

  • Use of Vinorelbine should be done with caution in patients with liver or kidney disease.

  • It should also be used cautiously in patients with existing bone marrow suppression.

Special Dietary and Lifestyle Recommendations

  • Eat a well-balanced diet rich in proteins, fruits, vegetables, and whole grains to help maintain your strength and immunity during cancer treatment.

  • Avoid consuming alcohol as it can potentially aggravate the side effects of Vinorelbine.

  • Rest and relaxation techniques such as meditation can help manage stress and fatigue associated with cancer treatment.

Frequently asked questions

Vinorelbine is a semi-synthetic medicine which has been derived from the periwinkle plant.

Vinorelbine, being a chemotherapy medicine, could potentially cause mood changes as part of its side effects. However, the specific impact on mood varies from patient to patient.

Vinorelbine does not directly affect hormonal balance. However, it may have indirect effects due to its impact on overall health and well-being.

There are no known natural alternatives that can provide the same effect as Vinorelbine. Always consult your doctor before starting any new medication or alternative therapy.

While taking Vinorelbine, it is crucial to maintain a healthy lifestyle and follow all recommendations given by your doctor. No specific lifestyle changes are mentioned related to this medicine.

Switching to another salt without consulting your doctor can be harmful as all medicines have their own side effects and benefits. Always discuss with your doctor about any concerns you may have about your medications.

Vinorelbine is not known to cause dependency; however, it is essential to use it as directed by your doctor for the prescribed duration of treatment.

Terms & Conditions

Available medicines for VINORELBINE
Neoben 10 MG Injection 1 ML
Neoben 10 MG Injection 1 ML
Neon Laboratories Ltd
Pack of 1 ML
₹952.23
MRP ₹1161.25
18.00% OFF
Neoben 50 MG Injection 1 ML
Neoben 50 MG Injection 1 ML
Neon Laboratories Ltd
Pack of 1 ML
₹3569.05
MRP ₹4352.50
18.00% OFF
Vinelbine 10 MG Injection 1 ML
Vinelbine 10 MG Injection 1 ML
Fresenius Kabi India Pvt Ltd
Pack of 1 ML
₹2470.14
MRP ₹3012.36
18.00% OFF
Vinelbine 50 MG Injection 5 ML
Vinelbine 50 MG Injection 5 ML
Fresenius Kabi India Pvt Ltd
Pack of 5 ML
₹10501.45
MRP ₹12806.65
18.00% OFF
Navelbine 10 MG Injection 1 ML
Navelbine 10 MG Injection 1 ML
Abbott Healthcare Pvt. Ltd
Pack of 1 ML
₹2829.00
MRP ₹3450.00
18.00% OFF
Zorelbin 50 MG Injection 5 ML
Zorelbin 50 MG Injection 5 ML
Alkem Laboratories Ltd.
Pack of 5 ML
₹9594.00
MRP ₹11700.00
18.00% OFF
Navelbine 50 MG Injection 5 ML
Navelbine 50 MG Injection 5 ML
Abbott Healthcare Pvt. Ltd
Pack of 5 ML
₹13853.90
MRP ₹16895.00
18.00% OFF
Cevin 10 MG Injection 1
Cevin 10 MG Injection 1
Health Biotech Limited
Pack of 1 UNIT
₹2111.50
MRP ₹2575.00
18.00% OFF

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