Trimetazidine
ANTIANGINALUses of Trimetazidine
- Trimetazidine is used to treat angina pectoris (chest pain caused by coronary disease. It is used in combination with other medicines to treat chest pain.
Side effects of Trimetazidine
- Dizziness
- Headache
- Weakness
- Abdominal pain
- Diarrhoea
- Indigestion
- Nausea
- Vomiting
- Itching
How Trimetazidine works
- Trimetazidine is an antianginal medication.
- Trimetazidine is a partial fatty acid oxidation inhibitor that helps the heart use glucose for energy instead of fatty acids by blocking a specific enzyme.
- It is beneficial because when the heart is not getting enough oxygen, using glucose requires less oxygen than the usual process involving fatty acids.
- By promoting glucose use, Trimetazidine ensures the heart has enough energy even during reduced oxygen supply, supporting proper energy metabolism in these conditions.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Trimetazidine can be taken orally (tablet and capsule).
Age And Dose Restrictions
- It is intended to be used by adults above 18 years.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to Trimetazidine. It is also contraindicated in patients with Parkinson's disease, parkinsonian symptoms, tremors, restless leg syndrome, and other movement disorders. It is also contraindicated in patients with severe renal impairment.
Medications To Avoid With This Drug
- Inform your doctor about the other prescription and non-prescription medicines you are taking.
Overdose And Missed Dose
- If you miss a dose of Trimetazidine, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
Management Of Side Effects
- Take it with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- This medication can make you feel dizzy and drowsy. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking it.
Use In Pregnancy And Lactation
- Caution is advised during pregnancy and breastfeeding.
Caution In Other Conditions
- Caution is advised in older adults and patients with close-angle glaucoma and kidney impairment.
Special Dietary And Lifestyle Recommendation
- Do not stop taking medication without consulting your doctor.
- Avoid smoking or any tobacco use. Smoking is a significant risk factor for cardiovascular disease and can counteract the benefits of Trimetazidine.
- Follow regular check-ups with your doctor to monitor your heart health and adjust treatment if needed.
- Maintain a healthy weight for overall heart health.
- Limit the intake of saturated and trans fats, cholesterol, and sodium to promote heart health.
Frequently asked questions
1. Is Trimetazidine blood thinner?
No, it is not a blood thinner. It is a medication used to treat chest pain.
2. Does Trimetazidine affect the kidney?
It may affect kidney function. However, individuals with pre-existing severe kidney impairment should consult their doctor, as dosage adjustments may be necessary.
3. How much time do Trimetazidine take to work?
The noticeable improvement in angina symptoms may occur within a few days to weeks of using this medication consistently. However, it may take several weeks for maximum improvement. Individual responses may vary.
4. Is Trimetazidine a habit-forming medicine?
No, it is not habit-forming and is generally safe when used as directed.
5. Does Trimetazidine affect fertility?
The use of this medication is not known to impair female fertility.
6. Is the Trimetazidine available over the counter, or do I need a prescription?
This medication usually requires a prescription and is not available over the counter.
7. Can Trimetazidine lower blood pressure?
This medication is not known to affect blood pressure.
8. Is Trimetazidine good for the heart?
Yes, this medication is beneficial for the heart as it improves energy metabolism, particularly during reduced oxygen supply, helping manage angina symptoms and supporting overall cardiovascular function.
9. How long to take Trimetazidine?
Your doctor determines the duration of this medication treatment on your medical condition. It is typically prescribed for the long-term management of stable angina, and the duration will be specified in your individual treatment plan.
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