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Teriparatide

Uses of Teriparatide

  • Teriparatide is mainly used to manage osteoporosis in postmenopausal women, men with primary or hypogonadal osteoporosis, and individuals with glucocorticoid-induced osteoporosis who are at high risk for fracture. It belongs to the group of anabolic agents.

Side effects of Teriparatide

  • Dizziness
  • Headache
  • Nausea
  • Leg cramps
  • Joint pain

How Teriparatide works

  • Teriparatide is a parathyroid hormone analogue.
  • It works by stimulating the formation of new bone, thereby increasing overall bone mass. This is achieved by the action of Teriparatide on the cells that are responsible for creating new bone. This helps in the strengthening weak and thin bones, reducing the risk of fractures.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor|

MSc (Applied Genetics)

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Teriparatide is available in the form of an injection to be administered via a subcutaneous route (injected under the skin).

Age and Dose Restrictions

  • Teriparatide is usually prescribed for adults.

Contraindications

  • Teriparatide is contraindicated in patients with hypersensitivity to any of its components. It is also contraindicated in patients with pre-existing hypercalcemia (high calcium level), severe kidney impairment, metabolic bone diseases other than osteoporosis, unexplained elevations of alkaline phosphatase, prior radiation therapy involving the skeleton, or skeletal malignancies or bone metastases.

Other Medications to Avoid

  • This medicine can interact with cardiac glycosides (e.g., digoxin), thiazide diuretics (e.g., hydrochlorothiazide and indapamide), and loop diuretics (e.g., furosemide).

Overdose and Missed Dose

  • Overdose of Teriparatide may result in symptoms such as nausea, vomiting, loss of appetite, and increased urination. If you observe these symptoms, inform your doctor immediately.
  • If you miss a dose of this medication, take it as soon as you remember. But if the time of the next dose is close, skip the missed dose and go back to regular schedule. Do not take two doses simultaneously.

Management of Side Effects

Most side effects of Teriparatide are temporary and generally harmless and resolve upon discontinuation of this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience injection site reactions such as redness or swelling, try to rotate the injection sites as directed by your doctor to avoid repeated trauma to the same area.
  • In case of nausea or vomiting, take this medicine with food as it can help to reduce these symptoms.
  • Increasing fluid intake may help reduce constipation caused by this medication.

Use in Driving and Operating Machinery

  • Teriparatide may cause dizziness. This could affect your ability to drive or operate machinery. If you experience dizziness after taking this medicine, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • Teriparatide should not be used during pregnancy and breastfeeding unless recommended by your doctor due to insufficient data on its safety. It's crucial to consult your doctor before using this medicine during pregnancy and breastfeeding.

Caution in Other Conditions

  • Patients with kidney conditions should exercise caution when taking Teriparatide due to the risk of hypercalcaemia (high calcium level). It should also be used with caution in patients with a history of bone cancer or other bone diseases due to the potential risk of osteosarcoma.

Special Dietary and Lifestyle Recommendations

  • It is advisable to follow a diet rich in calcium and vitamin D while taking this medication, as these nutrients are essential for bone health.
  • Regular monitoring of bone density is advised to assess the progress of osteoporosis management.
  • Limiting the intake of caffeine and alcohol, which can inhibit calcium absorption, is also recommended.
  • Smoking cessation is also advised as smoking can lower bone mineral density and increase fracture risk.

Frequently asked questions

Some individuals have reported weight gain while using Teriparatide. However, it is not a common side effect. If you notice substantial weight changes while taking this medicine, consult your doctor.

The time for noticeable improvements varies from person to person. However, regular bone density tests can help monitor the effectiveness of this medication.

Long-term use of Teriparatide can potentially increase the risk of osteosarcoma. Therefore, this medication is typically prescribed for a maximum duration of 2 years.

Store Teriparatide injections in the refrigerator at a temperature between 2°C to 8°C. Do not freeze the medication, and keep it out of reach of children. If you are travelling, carry the medication in a cooler with ice packs.

Combining Teriparatide with other osteoporosis medications like bisphosphonates or denosumab may provide additional benefits in treating osteoporosis. However, the combination should be carefully monitored by your doctor to avoid potential interactions or adverse effects.

Regular doctor visits are essential while using Teriparatide to monitor your response to treatment, bone density changes, and any potential side effects. Your doctor will determine the frequency of visits based on your individual health status and treatment progress.

Currently, there is no generic version of Teriparatide available. It is only marketed under brand names such as Forteo and Forsteo. If cost is a concern, discuss potential financial assistance or alternative treatment options with your healthcare provider.

Terms & Conditions

Available medicines for TERIPARATIDE
Gemtide 600mcg Disposable Pen 2.4ml
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Tricium Pth Injection 3ml
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Terifrac Injection 3ml
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Nu Pth 750mcg Injection 3ml
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₹4444.40
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Gemfrac Injection 1
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Bonista Pf Injection 2.4ml
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Bonmax Pth 750 MCG Cartridge 3 ML
Bonmax Pth 750 MCG Cartridge 3 ML
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Bonista Injection 3ml
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