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Tapentadol

OPIOID ANALGESIC

Uses of Tapentadol

Tapentadol is used for the relief of moderate to severe acute pain in adults. 

Side effects of Tapentadol

  • Headache
  • Dizziness
  • Sleepiness
  • Fatigue
  • Decreased appetite
  • Nausea
  • Constipation
  • Diarrhoea 
  • Vomiting

How Tapentadol works

Tapentadol works by acting on μ type of opioid receptors inside the brain and also inhibits the reuptake of a neurotransmitter called norepinephrine. Both these actions are responsible for the effective pain relief provided by this medicine.

Certified content

Written By

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Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Tapentadol can be taken orally (tablet, capsule) and nasally (nasal spray).

Age and Dose Restrictions

  • It is intended to be used by adults above 18 years of age.

Contraindications

  • It is contraindicated in patients with a history of hypersensitivity to Tapentadol. It is also contraindicated in patients with impaired pulmonary function, paralytic ileus, and severe kidney impairment. 

Other Medications To Avoid With This Medicine

  • Avoid taking centrally acting medications (clonidine) and monoamine oxidase inhibitors (phenelzine). These medications may alter the safety and effectiveness of Tapentadol.

Overdose and Missed Dose

  • Overdose can cause miosis, vomiting, cardiovascular collapse, consciousness disorders up to coma, convulsions and respiratory depression up to respiratory arrest. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of Tapentadol, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Use In Driving And Operating Machinery

  • Refrain from driving or operating machinery after using this medication.

Use in Pregnancy and Lactation

  • Tapentadol is not recommended during pregnancy and breastfeeding.

Caution In Other Conditions

  • Caution is advised in older adults, patients with a history of seizures, serotonin syndrome, debilitated patients, those suffering from conditions accompanied by hypoxia, hypercapnia, or upper airway obstruction and patients having increased intracranial pressure.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol consumption while on Tapentadol, as it may increase the risk of side effects.

Frequently asked questions

No, it should ideally not be taken before bed as it may rarely cause some respiratory symptoms.

Yes. it can lower your blood pressure when taken in excessive doses but, it is not meant for this purpose.

It is not indicated for patients with severe liver diseases as it can worsen them. Dose adjustment will be needed for such patients.

Yes, it is a narcotic medicine. 

Yes, it is a habit-forming medication.

It is not indicated for use in children below 18 years of age.

Terms & Conditions

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