Rizatriptan
Uses of Rizatriptan
Rizatriptan is used predominantly to manage acute migraine headaches in adults. It falls into the category of selective serotonin receptor agonists or triptans.
It has no secondary uses, as it is specifically designed to deal with migraines.
Side effects of Rizatriptan
Dizziness
Sleepiness
Tingling sensations
Fatigue
Nausea
How Rizatriptan works
Rizatriptan is a selective serotonin receptor agonist, also known as a triptan.
It works by binding to serotonin 5-HT1B and 5-HT1D receptors in the brain. This action leads to the narrowing of dilated blood vessels in the brain, which are often associated with migraine headaches. Furthermore, Rizatriptan inhibits the release of substances in the brain that can cause pain, nausea, and other symptoms associated with migraines. As a result, it provides relief from acute migraine pain and associated symptoms.
Certified content
Written By
BDS, MDS
Reviewed By
BAMS, APG, PG
Expert Advice
Dosage Forms Available
Rizatriptan can be taken orally (tablets).
Age and Dose Restrictions
This medicine is primarily meant for adults. It can also be given to children older than 12 years of age, under the guidance of a doctor.
Contraindications
Rizatriptan is contraindicated in patients with ischemic heart disease, coronary artery vasospasm, a history of stroke or transient ischemic attack, peripheral vascular disease, uncontrolled hypertension, and hemiplegic or basilar migraine.
Other Medications to Avoid
This medicine may interact with ergot-containing medicines (e.g., ergotamine, methysergide), other triptans (e.g., sumatriptan, zolmitriptan), and MAO inhibitors (e.g., phenelzine, selegiline).
Overdose and Missed Dose
Overdose of Rizatriptan can potentially cause serious effects like fainting, heart rhythm disturbances, and severe high blood pressure. In case of overdose, immediate medical attention should be sought.
If a dose of Rizatriptan is missed, take it as soon as you remember, but do not double the dose to make up for the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.
Drinking plenty of fluids can help manage dizziness caused by Rizatriptan.
Lying down in a quiet and dark room can aid in relieving dizziness and sleepiness.
Light physical activities like walking can help counter fatigue associated with this medicine.
Use in Driving and Operating Machinery
Rizatriptan may cause dizziness or sleepiness. If you experience these effects, avoid driving or operating heavy machinery until these symptoms subside.
Use in Pregnancy and Lactation
Rizatriptan is not recommended during pregnancy and lactation unless prescribed by the doctor. It is always recommended to consult your doctor before taking this medicine during pregnancy or breastfeeding.
Caution in Other Conditions
Patients with phenylketonuria should be cautious with Rizatriptan orally disintegrating tablets due to phenylalanine, and those with heart disease or risk factors should use Rizatriptan with caution.
Special Dietary and Lifestyle Recommendations
Avoiding potential migraine triggers such as stress, certain foods and beverages, lack of sleep and physical exertion can also help in managing migraines.
Apply a cold compress or ice pack to your forehead for about 15 minutes to ease pain and reduce blood vessel dilation.
Avoid skipping meals, as irregular eating patterns can contribute to migraines.
Frequently asked questions
Is Rizatriptan available over the counter, or do I need a prescription?
Rizatriptan is a prescription medicine and is not available over the counter. You should always consult your doctor before starting any new medication.
Are there any natural alternatives to Rizatriptan for managing migraines?
Yes, there are several natural alternatives that may help manage migraines. Magnesium, riboflavin (Vitamin B2), coenzyme Q10 (CoQ10), peppermint oil, lavender oil, acupuncture, and yoga can help reduce the chances of migraine headaches. However, remember, these alternatives are not substitutes for Rizatriptan. Take this medicine as prescribed by the doctor, and always consult your doctor before making any changes to your migraine management plan.
Can Rizatriptan affect my mood?
Rizatriptan does not typically affect mood. However, each individual may react differently to medication. If you notice any changes in your mood or behaviour after starting Rizatriptan, consult your doctor immediately.
How long does the effect of Rizatriptan last in the body?
Rizatriptan has a half-life of about 2-3 hours, which means most of it is eliminated from the body within this duration.
Will taking Rizatriptan affect my menstrual cycle?
Rizatriptan is not known to affect the menstrual cycle directly. However, if you notice any changes in your menstrual cycle after starting on Rizatriptan, consult your doctor.
Is Rizatriptan a steroid?
No, Rizatriptan is not a steroid. It belongs to a class of medicines called selective serotonin receptor agonists, also known as triptans.
Will Rizatriptan affect fertility?
Rizatriptan is not known to have any direct effect on fertility. As with any medication, if you have concerns about your fertility, it is recommended to consult your doctor.
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