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Ranibizumab

Uses of Ranibizumab

  • The primary use for Ranibizumab is in managing various eye conditions including wet age-related macular degeneration (AMD), macular oedema following retinal vein occlusion, diabetic macular oedema, and diabetic retinopathy in patients with diabetic macular oedema. It belongs to the group of anti-vascular endothelial growth factor (VEGF) agents.

Side effects of Ranibizumab

  • Conjunctival haemorrhage (bleeding in the white of the eye after injection)

  • Eye pain

  • Vitreous floaters

  • Blurred vision

  • Increased intraocular pressure

How Ranibizumab works

  • Ranibizumab is an anti-VEGF (vascular endothelial growth factor) agent. It performs its function by inhibiting VEGF-A, a specific protein that encourages the development of abnormal blood vessels in the eye. These unusual vessels can cause swelling and leakage. By blocking VEGF-A, Ranibizumab decreases these issues, effectively managing the risk of vision loss if left unaddressed.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer|

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Ranibizumab is available in the form of injection. It is administered through the intravitreal route, meaning the medicine is injected directly into the eye.

Age and Dose Restrictions

  • This medicine is meant for adult use.

Contraindications

  • Ranibizumab is contraindicated in patients with active eye infections or periocular infections.

  • It should not be used in eyes with active intraocular inflammation.

  • It is also contraindicated in patients who are hypersensitive to Ranibizumab or any of its components.

Other Medications to Avoid

  • This medicine may interact with other anti-vascular endothelial growth factor agents (such as bevacizumab and aflibercept).

Overdose and Missed Dose

  • Overdose with Ranibizumab, particularly due to over-injection, can lead to increased intraocular pressure, inflammation, or infection. In case of suspected overdose, monitor the patient for signs or symptoms of adverse reactions and manage them symptomatically.

  • If a dose is missed, the patient should consult their doctor to discuss when to administer the next dose without doubling it.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For mild eye irritation or redness, resting the eyes can help relieve discomfort.

Use in Driving and Operating Machinery

  • Ranibizumab may cause vision changes. You are advised not to drive or operate heavy machinery until you know how this medicine affects your vision.

Use in Pregnancy and Lactation

  • Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with a history of thromboembolic events should exercise caution when using Ranibizumab due to the potential risk of arterial thromboembolic events associated with intravitreal use of VEGF inhibitors.

Special Dietary and Lifestyle Recommendations

  • Maintain a diet rich in omega-3 fatty acids, zinc, and antioxidants which are known to support eye health. Foods like fish, nuts, seeds, and green leafy vegetables are advisable.

  • Regular eye examinations are recommended to monitor the condition being treated with Ranibizumab.

  • Smoking cessation is crucial as smoking can exacerbate conditions like macular degeneration.

  • Managing underlying conditions such as diabetes through diet, exercise, and medication adherence can help improve outcomes when treating diabetic macular oedema or diabetic retinopathy with Ranibizumab.

Frequently asked questions

No, Ranibizumab is not a steroid. It is an anti-vascular endothelial growth factor (VEGF) agent used to manage several eye conditions.

The research data provided does not mention any effects of Ranibizumab on sleep. However, it is always best to consult your doctor for any concerns related to your medication and sleep patterns.

No specific studies or data suggest that Ranibizumab has an impact on fertility. If you have fertility concerns while taking this medicine, please consult your doctor.

There are no specific diet restrictions mentioned in the research data while taking Ranibizumab. However, it is always a good idea to discuss your diet and lifestyle with your doctor when starting any new medication.

Ranibizumab is usually administered once a month or as per the condition being managed and the patient's response. Your doctor will determine the suitable frequency based on your case.

The onset of action for Ranibizumab may vary based on the individual patient's response and the specific eye condition being managed.

Ranibizumab is administered by your doctor through an injection into the eye, so the timing will be determined by your doctor's schedule and your appointment timing.

Terms & Conditions

Available medicines for RANIBIZUMAB
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Lucentis 0.5 MG Injection 0.05 ML
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Ranieyes 10 MG Injection 0.23 ML
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Visumab 0.5 MG Injection 0.23 ML
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