The primary use of Quetiapine is for the management of mental health conditions such as schizophrenia and bipolar disorder. It belongs to the group of medicines known as atypical antipsychotics.
Secondary uses of Quetiapine include the management of depressive episodes associated with bipolar disorder and as an adjunct treatment for major depressive disorder in adults. Doctors may also prescribe it off-label for conditions such as anxiety disorders, post-traumatic stress disorder (PTSD), delirium, autism, and obsessive-compulsive disorder (OCD).
Drowsiness
Dry mouth
Dizziness
Constipation
Increased appetite and weight gain
Quetiapine is an atypical antipsychotic.
It works primarily by blocking two types of neurotransmitter receptors in the brain: dopamine type 2 (D2) and serotonin type 2A (5-HT2A). These are chemical messengers that help neurons, or nerve cells, communicate with each other. By blocking these receptors, Quetiapine helps to balance the levels of dopamine and serotonin, thereby reducing symptoms of mental disorders.
MD Ayurveda
BMS, FMC, MD Resident
Quetiapine is available for oral use in the form of immediate-release tablets. It is also available in the form of extended-release tablets which allow for once-daily dosing.
This medicine is indicated for adults and adolescents aged 13 years and above.
Quetiapine is contraindicated in patients with known hypersensitivity to Quetiapine or any of the excipients found in its formulation.
Additionally, it is contraindicated in patients diagnosed with dementia-related psychosis due to an increased risk of mortality.
Quetiapine can interact with antifungal medications (such as ketoconazole, itraconazole, and fluconazole), antibiotics (like erythromycin), and protease inhibitors which are used in the treatment of HIV infection.
It is also important to note that the efficacy of Quetiapine can be decreased with the concurrent use of medications like phenytoin, carbamazepine, and rifampin.
An overdose of Quetiapine may lead to symptoms such as drowsiness, sedation, tachycardia, hypotension, and QT prolongation. In case of an overdose, it is crucial to seek immediate medical attention.
If you forget a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
Drinking plenty of water may help manage constipation that may occur as a side effect.
If you experience drowsiness, it can help to take the medicine at bedtime.
Quetiapine may cause dizziness or drowsiness. Therefore, caution is advised when driving or operating heavy machinery until you know how this medicine affects you.
Quetiapine falls under Pregnancy Category C, implying potential risk to the foetus. Therefore, it should only be used during pregnancy if the benefits outweigh the risks.
As Quetiapine is excreted in human breast milk, breastfeeding while on this medication is not recommended.
Patients with liver impairment may need dose adjustments of Quetiapine due to altered metabolism and elimination of the medicine.
Quetiapine should also be used with caution in patients with a known history of seizures, as it may lower the seizure threshold.
Regular intake of a balanced diet with adequate fruits and vegetables can help support overall health and well-being.
Limiting consumption of caffeine and alcohol can help manage symptoms of conditions that Quetiapine is prescribed for, such as anxiety disorders and bipolar disorder.
Regular physical activity can promote overall physical health and help manage symptoms of depression.
Adequate sleep is important for maintaining mental health, particularly for individuals with conditions like schizophrenia and bipolar disorder. Creating a sleep-friendly environment and maintaining regular sleep schedules can be beneficial.
Stress management techniques like yoga, meditation or deep-breathing exercises can help manage symptoms of anxiety disorders or bipolar disorder.
Frequently asked questions
While Quetiapine is used to manage symptoms of certain mental disorders, it may cause anxiety in some people. However, everyone reacts differently to medications.
Quetiapine can help to improve mood disorders such as bipolar disorder and depression by balancing the neurotransmitters in the brain.
Quetiapine may affect your cognitive function, including your ability to concentrate and remember information. Always discuss any concerns with your doctor.
Stopping Quetiapine abruptly may lead to withdrawal symptoms such as nausea and insomnia. It is important to gradually taper off the medicine under the supervision of your doctor.
Quetiapine may cause increased appetite and weight gain. If you notice significant weight changes while taking this medicine, consult your doctor.
Yes, since Quetiapine acts on neurotransmitters in the brain like serotonin and dopamine, it can help to balance mood and reduce symptoms of mental health disorders such as depression and mania.
Yes, Quetiapine is a prescription-only medication as it is used for the management of serious mental health conditions and should only be taken under the supervision of a doctor.
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