Pitavastatin
Uses of Pitavastatin
Pitavastatin is primarily used to manage high levels of cholesterol in the blood (hyperlipidemia), in adults and children above 6 years old, and is a member of the statin group of medicines.
It is also used as an adjunctive therapy alongside diet changes to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides in patients with primary hyperlipidemia or mixed dyslipidemia. Additionally, it finds use as an adjunctive therapy to diet and other LDL-lowering therapies in patients with Homozygous Familial Hypercholesterolemia (HoFH).
Side effects of Pitavastatin
Constipation
Muscle pain
Back pain
Diarrhoea
How Pitavastatin works
Pitavastatin is a type of cholesterol-lowering medicine known as a statin.
It works by inhibiting an enzyme called HMG-CoA reductase in the body. This enzyme plays a key role in the production of cholesterol. By blocking this enzyme, Pitavastatin effectively reduces the level of harmful low-density lipoprotein (LDL) cholesterol and triglycerides in your blood. At the same time, it increases the level of beneficial high-density lipoprotein (HDL) cholesterol. This helps to maintain an optimum balance of cholesterol in your body and lower the risk of heart disease.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Pitavastatin can be taken orally (tablet).
Age and Dose Restrictions
Pitavastatin is prescribed to adults and children aged 6 years and above.
Contraindications
Pitavastatin is contraindicated in patients with active liver disease, including unexplained persistent elevations in hepatic transaminases. It is also contraindicated in those who have known hypersensitivity to Pitavastatin or any of its components.
Other Medications to Avoid
Pitavastatin may interact with immunosuppressive agents (such as cyclosporine), macrolide antibiotics (like erythromycin), antituberculosis medicines (like rifampin), antifungal agents (including itraconazole), and fibric acid derivatives (such as gemfibrozil).
Overdose and Missed Dose
An overdose of Pitavastatin may lead to excessive lowering of cholesterol levels in the blood. If an overdose is suspected, one should consult a doctor immediately.
In case you miss a dose of Pitavastatin, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects are temporary, generally harmless, and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
For nausea or upset stomach, taking the medication with food can help alleviate these symptoms.
Drinking plenty of water can help manage constipation.
Maintaining good body posture may help manage back pain.
Rest and relaxation techniques can help manage headaches and dizziness.
Use in Driving and Operating Machinery
Pitavastatin does not usually affect your ability to drive or operate heavy machinery. However, should you feel dizzy or have reduced mental alertness after taking this medicine, it is advised to refrain from driving or operating machinery.
Use in Pregnancy and Lactation
Pitavastatin is contraindicated during pregnancy and lactation due to potential harm to the fetus or infant. It is advised to consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Caution in Other Conditions
Patients with renal or hepatic conditions should exercise caution when taking Pitavastatin as it may require dose adjustment in these patients.
Special Dietary and Lifestyle Recommendations
Adopting a low-fat, low-cholesterol diet is beneficial for patients taking Pitavastatin.
Regular monitoring of cholesterol levels is encouraged to assess the effectiveness of the treatment.
Frequently asked questions
Is Pitavastatin a steroid?
No, Pitavastatin is not a steroid. It is a lipid-lowering medication belonging to the statin class of medicines.
Does Pitavastatin have any effect on sleep?
Different individuals may experience different side effects and it is always advisable to observe any abnormal changes after starting the medicine and discuss them with your doctor.
Will Pitavastatin affect fertility?
Pitavastatin has not been reported to affect fertility in humans. However, if you are planning a pregnancy or having difficulties in conceiving, please discuss this with your doctor.
Is it safe to take Pitavastatin daily?
Yes, it is safe to take Pitavastatin daily as long as it is prescribed by your doctor. Always follow your doctor's instructions regarding dosage and duration of treatment.
How much time does Pitavastatin take to work?
Pitavastatin starts working soon after ingestion but the noticeable effects on cholesterol levels may take several weeks or months depending on individual patient factors and the severity of the condition.
What is the best time to take Pitavastatin?
Pitavastatin can be taken at any time of the day but it should be taken at the same time each day for optimum results. Always follow your doctor's instructions on how to take this medication.
Can I stop taking Pitavastatin if my cholesterol levels decrease?
It is important not to stop taking Pitavastatin without consulting your doctor, even if your cholesterol levels have improved. Stopping abruptly could lead to a rebound increase in cholesterol levels.
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