Nimodipine
Uses of Nimodipine
The primary use of Nimodipine is to manage subarachnoid haemorrhage (SAH), which is a type of bleeding in the brain. It belongs to the class of medicines known as calcium channel blockers.
There are no secondary uses for this medication. It is specifically used for managing SAH to improve blood flow to the brain and reduce the risk of complications and brain damage.
Side effects of Nimodipine
Low blood pressure
Headache
Nausea
Swelling (oedema)
Dizziness
How Nimodipine works
Nimodipine is a calcium channel blocker.
It operates by blocking the calcium channels present in the walls of blood vessels, particularly in the brain. This action leads to the relaxation and expansion of these blood vessels, which, in turn, enhances the blood flow to areas of the brain impacted by a haemorrhage.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Nimodipine is available for use via the oral route in the form of capsules and an oral solution.
Age and Dose Restrictions
Nimodipine is intended for adults. The age range is from 18 years of age onwards.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to Nimodipine or other dihydropyridine calcium channel blockers.
It is also contraindicated for patients with hypotension and heart failure.
Other Medications to Avoid
Nimodipine may interact with several medications, including antifungal medicines (such as ketoconazole), anticonvulsants (like phenytoin or carbamazepine), antibiotics (such as erythromycin), and other calcium channel blockers (like diltiazem or verapamil).
Overdose and Missed Dose
An overdose of Nimodipine may result in severe hypotension or heart failure. In such a situation, immediate medical attention is necessary.
If you miss a dose of this medication, take it as soon as you remember. However, do not double the dosage to make up for a missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For headaches, rest and drink plenty of fluids.
For nausea, try taking this medication with food.
Use in Driving and Operating Machinery
Nimodipine may cause dizziness or fatigue. Therefore, you should avoid driving or operating heavy machinery if you experience these side effects.
Use in Pregnancy and Lactation
It is advised to consult a doctor before using Nimodipine during pregnancy and breastfeeding.
Caution in Other Conditions
Patients with severe hepatic impairment should exercise caution when taking Nimodipine.
Special Dietary and Lifestyle Recommendations
Avoid consumption of grapefruit and grapefruit juice as they can increase Nimodipine concentrations in the body, potentially leading to adverse effects.
Maintain a balanced diet and adequate hydration.
Regular monitoring of blood pressure is recommended to manage the underlying condition effectively.
Frequently asked questions
Can I start taking Nimodipine on my own?
No, you should not start taking Nimodipine without consulting your doctor. This medicine is usually prescribed by a doctor based on your medical condition.
Is Nimodipine a steroid?
No, Nimodipine is not a steroid. It is a type of medicine known as a calcium channel blocker.
Does Nimodipine have any effect on mood?
Nimodipine is not directly associated with affecting mood. If you experience unusual mood swings while taking Nimodipine, please consult your doctor.
Can I get addicted to Nimodipine?
No, Nimodipine does not cause physical or psychological dependency as it is not a habit-forming medicine.
How long does Nimodipine remain in the body?
The half-life of Nimodipine is approximately 8-9 hours, which means half the medicine is eliminated from the body within this time. However, it may take several half-lives for the medicine to be completely removed from your system.
Are there natural alternatives to Nimodipine?
While there might be natural products that help improve brain health, they cannot replace the specific action of Nimodipine in managing subarachnoid haemorrhage. Always consult your doctor before adding any herbal or natural remedies to your regimen.
How quickly does Nimodipine start working?
Nimodipine is rapidly absorbed from the gastrointestinal tract and reaches peak levels in the blood within 1-2 hours after ingestion.
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