Nateglinide
Uses of Nateglinide
The main use of Nateglinide is to manage type 2 diabetes in adults. This medicine belongs to the group of medications known as meglitinides.
In addition to being used on its own, Nateglinide is often used in combination with other diabetes medications like metformin to improve glycemic control.
Side effects of Nateglinide
Upper respiratory tract infection
Back pain
Flu symptoms
Dizziness
Diarrhoea
How Nateglinide works
Nateglinide is a member of the meglitinides therapeutic category.
It works by stimulating the pancreas to release insulin in response to meals. By enhancing insulin secretion, Nateglinide helps lower blood sugar levels, especially after eating.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Nateglinide is available for use via oral route in the form of tablets.
Age and Dose Restrictions
This medicine is meant for adults. It is not recommended for the treatment of type 1 diabetes or diabetic ketoacidosis in children.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to Nateglinide or its inactive ingredients.
Other Medications to Avoid
Nateglinide may interact with rifampin (a cytochrome P450 2C9 inducer), which may reduce its efficacy.
It may also interact with CYP2C9 inhibitors like fluconazole which may elevate Nateglinide levels.
Before starting any prescription or over-the-counter medications, it is critical to consult a doctor.
Overdose and Missed Dose
An overdose of Nateglinide can cause severe hypoglycemia which requires immediate medical treatment.
If you forget to take your dose of Nateglinide, take it as soon as you remember but do not double the dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage side effects such as diarrhoea.
Side effects like dizziness can be managed by sitting down or lying down until the feeling passes.
Use in Driving and Operating Machinery
Nateglinide may cause dizziness as a side effect and thus, may affect your ability to drive or operate heavy machinery.
Use in Pregnancy and Lactation
The use of this medicine during pregnancy or breastfeeding is not recommended without a doctor's advice. It is best to consult your doctor before taking this medication if you are pregnant or nursing.
Caution in Other Conditions
Caution is advised in patients with liver or kidney disease due to possible medicine accumulation.
Caution is also advised in elderly, debilitated, or malnourished patients, and those with adrenal or pituitary insufficiency, as they may be more susceptible to hypoglycemia.
Special Dietary and Lifestyle Recommendations
Eating a healthy diet rich in fruits, vegetables, lean proteins, and whole grains can help manage your blood sugar levels.
Regular physical activity can also help keep your blood sugar levels in check.
Avoid smoking and limit your alcohol intake as these can increase your risk of hypoglycemia.
Frequently asked questions
Is Nateglinide a steroid?
No, Nateglinide is not a steroid. It is a medication that belongs to the class of meglitinides and is used for managing type 2 diabetes in adults.
Can Nateglinide affect my mood?
Nateglinide's primary function is to help manage blood sugar levels and it does not directly impact mood. However, fluctuating blood sugar levels can indirectly affect mood. If you notice significant mood changes, consult your doctor.
Is Nateglinide a long-term medication?
Yes, Nateglinide is often prescribed as a long-term medication to manage type 2 diabetes, along with diet and exercise. Your doctor will provide guidance based on your health condition.
Does Nateglinide cause weight gain?
Nateglinide does not directly cause weight gain. However, managing type 2 diabetes often involves lifestyle changes, including diet and exercise, which can influence your weight.
Does Nateglinide work immediately?
Yes, Nateglinide starts working quickly, within 20 minutes of taking the dose to manage blood sugar levels that is why it is usually taken before meals.
Can I take Nateglinide if I am fasting?
If you are fasting for an extended period, consult your doctor before taking Nateglinide as skipping meals can affect the management of blood sugar level by this medicine.
What are natural alternatives to Nateglinide?
While some lifestyle changes like a healthy diet and regular exercise can help manage blood sugar levels, they cannot replace the action of medicines like Nateglinide. Always consult your doctor before making any changes to your medication.
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