Natamycin
Uses of Natamycin
Natamycin is used to manage fungal infections, particularly in the eye. It falls under the category of polyene antibiotics.
Aside from its medical uses, Natamycin is also employed as a food preservative. It helps prevent mould growth in certain dairy products like cheese.
Side effects of Natamycin
Eye irritation
Burning sensation
Stinging sensation
Temporary blurred vision
Rare allergic reactions like itching, swelling, or rash around the eyes
How Natamycin works
Natamycin is a naturally occurring antifungal agent.
It functions by binding to ergosterol, a primary component found in the cell membranes of fungi. This interaction disrupts the normal structure of the fungal cell membrane, causing leakage of vital cellular components and eventually leading to cell death. By selectively targeting ergosterol, a substance not present in human cells, Natamycin can prevent fungal growth without harming human tissues.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Natamycin is available as an ophthalmic suspension, which is instilled directly into the eye.
In the food industry, Natamycin is used in the form of a powder or solution for preservation purposes.
Age and Dose Restrictions
Natamycin is primarily prescribed for use in adults.
Contraindications
Natamycin is contraindicated in individuals with known hypersensitivity to this medicine or any of its components.
It is also contraindicated for patients with known allergies to polyene antibiotics.
Other Medications to Avoid
Natamycin may interact with other antifungal agents (e.g., amphotericin B and clotrimazole).
If other ophthalmic medications are being used concurrently with Natamycin, they should be administered at least 5 minutes apart to avoid dilution or washout of either medicine.
Overdose and Missed Dose
Overdosing on Natamycin is unlikely due to its low absorption rate. However, in case of accidental ingestion, patients should drink plenty of water and seek medical advice.
If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.
If you experience eye irritation after applying Natamycin eye drops, rinsing the eye with water may help alleviate discomfort.
Patients experiencing temporary blurred vision after application should rest their eyes until their vision clears.
Use in Driving and Operating Machinery
Some patients may experience temporary blurred vision after applying Natamycin eye drops. As such, it is recommended to avoid driving or operating machinery until the vision clears.
Use in Pregnancy and Lactation
The safety of Natamycin during pregnancy and lactation has not been established. Pregnant or breastfeeding women should consult a doctor before using this medicine.
Caution in Other Conditions
No specific medical conditions have been identified for which caution needs to be taken while using Natamycin. However, as with any medicine, patients with chronic health conditions should consult their doctor before starting treatment.
Special Dietary and Lifestyle Recommendations
Individuals should maintain a high standard of eye hygiene to help manage fungal eye infections. This can include regularly washing hands before touching the eyes to prevent further infection.
Patients should avoid wearing contact lenses while using Natamycin for several days after stopping treatment to allow the eye to heal.
In the case of food preservation, manufacturers should ensure that their products are stored at appropriate temperatures to minimise mould growth and other microorganisms.
Frequently asked questions
Is Natamycin a steroid?
No, Natamycin is not a steroid. It is a naturally occurring antifungal agent and belongs to the class of polyene antibiotics.
Does Natamycin have any effect on sleep?
There is no information available suggesting that Natamycin has any direct effect on sleep.
Is Natamycin available over-the-counter, or do I need a prescription?
Natamycin is usually available only with a doctor's prescription and is not typically sold over-the-counter.
What is the duration of treatment with Natamycin?
The duration of treatment with Natamycin depends on the severity and type of infection being treated. Typically, treatment lasts for 2-3 weeks or until the infection resolves.
Is it safe to take Natamycin daily?
Yes, it is safe to take Natamycin daily as per your doctor's prescription and directions. Always adhere to the prescribed dosage and do not self-medicate.
How much time does Natamycin take to work?
Natamycin starts working immediately upon application, but visible improvement in symptoms may take several days. Most fungal eye infections require 2-3 weeks of treatment for complete resolution.
What is the best time to take Natamycin?
Natamycin should be taken as directed by your doctor. The timing could vary depending on the severity of the infection and the specific formulation used.
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