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Nalbuphine

Uses of Nalbuphine

  • Nalbuphine is primarily used for managing moderate to severe pain and it belongs to opioid agonist-antagonist analgesic medications.

  • This medicine may also be used to alleviate pain before and after surgery and during childbirth. Other uses may be determined by the doctor as relevant to your health condition.

Side effects of Nalbuphine

  • Sedation

  • Sweating

  • Nausea and vomiting

  • Dizziness

  • Headache

How Nalbuphine works

  • Nalbuphine is an opioid agonist-antagonist that functions by binding to specific proteins known as opioid receptors, located in the brain, spinal cord, and gastrointestinal tract. By attaching to these receptors, nalbuphine blocks the transmission of pain signals from the nerves to the brain, effectively reducing the sensation of pain.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 Years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • This medicine is available as a liquid formulation for infusion (subcutaneous, intramuscular, or intravenous)routes.

Age and Dose Restrictions

  • This medicine is intended for use in adults and children.

Contraindications

  • Nalbuphine is contraindicated in patients who have known hypersensitivity to the medicine.

  • It is also contraindicated in individuals with severe respiratory depression.

Other Medications to Avoid

  • This medicine may interact with benzodiazepines and other central nervous system (CNS) depressants (e.g., alcohol, sedatives), serotonergic drugs (e.g., SSRIs, tricyclic antidepressants), monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine, tranylcypromine), muscle relaxants (e.g., cyclobenzaprine), and anticholinergic drugs (e.g., atropine).

Overdose and Missed Dose

  • An overdose of Nalbuphine may result in severe respiratory depression, extreme drowsiness, and hypotension. In case of a suspected overdose, seek immediate medical attention.

  • If you miss a dose of this medicine, administer it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing Nalbuphine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea or vomiting, it may help to administer this medication with food.

  • If you experience dizziness or lightheadedness, sit or lie down until the symptoms pass.

  • Keep yourself well hydrated to manage headaches.

Use in Driving and Operating Machinery

  • Nalbuphine may cause dizziness, drowsiness or blurred vision which could affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how this medication affects you.

Use in Pregnancy and Lactation

  • This medicine is not recommended during pregnancy and breastfeeding unless specifically advised by a healthcare professional. Consult a doctor before taking this medicine during these periods.

Caution in Other Conditions

  • Patients with kidney or liver disease should use Nalbuphine with caution as adjustments in dosing might be required.

  • Caution should also be exercised in patients with respiratory issues, as this medicine can cause respiratory depression.

Special Dietary and Lifestyle Recommendations

  • A balanced diet rich in fruits, vegetables, lean proteins, and whole grains can contribute to overall health and well-being.

  • Adequate hydration is important for overall health and can help manage potential side effects such as dry mouth or constipation.

Frequently asked questions

No, Nalbuphine is not a steroid. It is an opioid analgesic, a type of medication used to manage moderate to severe pain.

Yes, Nalbuphine may cause sedation, which could affect your sleep patterns or make you feel drowsy or sleepy.

Nalbuphine is not associated with affecting fertility. However, it should be used under the guidance of a doctor if you are planning to conceive or experiencing fertility issues.

Nalbuphine should be administered as prescribed by your doctor. Its safety for daily use depends on the individual's health condition and the duration of therapy recommended by the doctor.

The onset of action for Nalbuphine varies among individuals but generally, it starts working in approximately 15 minutes after administration.

The best time to administer Nalbuphine is as advised by your doctor, based on your specific medical conditions and requirements.

Nalbuphine is a prescription medication and is not available over the counter.

Terms & Conditions

Available medicines for NALBUPHINE
Rubuphine 20 MG Injection 1 ML
Rubuphine 20 MG Injection 1 ML
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₹52.32
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Rubuphine 10 MG Injection 1 ML
Rubuphine 10 MG Injection 1 ML
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Ruffy 10 MG Injection 1 ML
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₹31.16
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Nacphin 20 MG Injection 1 ML
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₹217.02
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Ruffy 20 MG Injection 1 ML
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Nacphin 10 MG Injection 1 ML
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₹35.42
MRP ₹43.20
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Nalfy 10 MG Injection 1 ML
Nalfy 10 MG Injection 1 ML
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₹36.90
MRP ₹45.00
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Nalfy 20 MG Injection 1 ML
Nalfy 20 MG Injection 1 ML
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₹54.94
MRP ₹67.00
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