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Meropenem + Sulbactam

Uses of Meropenem + Sulbactam

  • Meropenem + Sulbactam is primarily used for the management of severe bacterial infections. It is part of the carbapenem and beta-lactamase inhibitor group of medicines.

  • This medicine is also used to manage conditions such as respiratory tract infections like pneumonia and bronchitis, urinary tract infections, intra-abdominal infections, gynaecological infections, skin and soft tissue infections, septicemia, bacteremia, and meningitis and other central nervous system infections.

Side effects of Meropenem + Sulbactam

  • Diarrhoea

  • Nausea and vomiting

  • Headache

  • Dizziness

  • Pain and inflammation at the injection site

How Meropenem + Sulbactam works

  • Meropenem is used to treat bacterial infections of the skin and stomach in adults and children. Meropenem belongs to a group called carbapenem antibiotics. It works by halting the production of bacterial cell walls, which are crucial for their survival. Without these walls, the bacterial cells cannot maintain their structure and eventually break down, leading to their death.

  • Sulbactam is used in the treatment of severe bacterial infections. Sulbactam falls under the beta-lactamase inhibitors category. It safeguards Meropenem by binding itself to specific enzymes in bacteria that could otherwise destroy Meropenem. This allows Meropenem to perform its task unhindered.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer|

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Meropenem + Sulbactam is available for use via the parenteral route (injection).

Age and Dose Restrictions

  • This medication is meant for adults and children 3 months of age and older. For paediatric population, dose adjustment is considered based on the child's weight.

Contraindications

  • Meropenem + Sulbactam is contraindicated in patients with known hypersensitivity to the components of this medication, namely carbapenems, penicillin's, cephalosporins, or beta-lactamase inhibitors.

Other Medications to Avoid

  • This combination may interact with anticonvulsants (such as valproic acid and divalproex sodium), and with renal excretion aiding compounds (like probenecid).

Overdose and Missed Dose

  • An overdose of Meropenem + Sulbactam could potentially lead to symptoms such as seizures, confusion and involuntary eye movements. If you suspect an overdose, contact your doctor immediately.

  • If you miss a dose of this medication, administer it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage common side effects such as diarrhoea, nausea, or vomiting, try taking the medication with food.

  • For managing headaches or dizziness, ensure that you are well hydrated and rest adequately.

Use in Driving and Operating Machinery

  • Meropenem + Sulbactam may cause side effects such as dizziness or drowsiness, which could affect your ability to drive or operate heavy machinery. It is advised to refrain from such activities until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Meropenem + Sulbactam should be used during pregnancy and lactation only if the benefits to the mother outweigh the potential risks to the foetus or infant. Always consult your doctor before using this medicine in pregnancy and breastfeeding.

Caution in Other Conditions

  • Patients with renal impairment should exercise caution when taking Meropenem + Sulbactam as dose adjustments may be necessary based on creatinine clearance rates.

  • Similarly, patients with a history of seizures or CNS disorders should be closely monitored while on this medication.

Special Dietary and Lifestyle Recommendations

  • Maintain good hydration throughout treatment to support kidney function, as this medication is primarily eliminated via renal excretion.

  • Good personal hygiene practices are vital when dealing with bacterial infections.

Frequently asked questions

No, Meropenem + Sulbactam does not contain steroids. It is a combination of two active ingredients: Meropenem, a carbapenem antibiotic, and Sulbactam, a beta-lactamase inhibitor.

While some patients may experience side effects such as dizziness with Meropenem + Sulbactam, it is not specifically known to cause sleep disturbances. If you experience persistent sleep problems while taking this medication, please consult your doctor.

No, Meropenem + Sulbactam is a prescription medicine. It can only be obtained with a doctor's prescription.

While there might be natural remedies that can support your immune system, they should not be used as a substitute for Meropenem + Sulbactam or any other prescribed antibiotics. Always consult your doctor before starting any new treatment.

Meropenem + Sulbactam should be taken as advised by your doctor. The timing can depend on various factors such as the severity of infection and renal function.

Meropenem + Sulbactam should be administered as recommended by your doctor based on your condition and the severity of the infection.

The time taken by Meropenem + Sulbactam to show its effect may vary depending on the type and severity of infection. Consult your doctor for more information.

Terms & Conditions


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