Melphalan
Uses of Melphalan
It is primarily used in the management of certain types of cancer, specifically multiple myeloma and ovarian cancer. It belongs to a class of anti-cancer medicines known as alkylating agents.
In addition, it is also indicated for managing malignant melanoma of the eye that has spread to the liver. It may also be used off-label for other types of cancer as determined by your doctor.
Side effects of Melphalan
Nausea and vomiting
Diarrhoea
Mouth sores
Loss of appetite
Fatigue and weakness
Hair loss (usually reversible)
How Melphalan works
Melphalan is an alkylating agent classified as a chemotherapeutic medication. It works by cross-linking DNA strands within cancer cells, which interferes with their ability to divide and reproduce, thereby inhibiting the growth and spread of cancer.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
This medicine can be taken orally in the form of tablets.
It is also available as an injectable solution and powder, which is administered through the intravenous route by a healthcare professional.
Age and Dose Restrictions
It is intended for use in adults over the age of 18.
Contraindications
Melphalan is contraindicated in patients with a known allergy to it.
It should not be given to patients who have severely depressed bone marrow function.
Other Medications to Avoid
It may interact with antibiotics (such as nalidixic acid), immunosuppressants (such as cyclosporine), and antacids (like cimetidine).
Overdose and Missed Dose
An overdose may cause severe nausea, vomiting, diarrhoea, mouth sores, and dangerously low blood cell counts. If you observe these symptoms, inform your doctor immediately.
If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help to manage some of the side effects like nausea and vomiting.
Taking the medicine with food might reduce the severity of gut-related side effects, like diarrhoea.
Use in Driving and Operating Machinery
This medicine can cause side effects such as dizziness and tiredness, which may affect your ability to drive or operate heavy machinery. Avoid these activities if you feel unwell.
Use in Pregnancy and Lactation
It is recommended to consult a doctor before using this medicine during pregnancy or breastfeeding as it may harm the baby.
Caution in Other Conditions
Patients with liver or kidney disease should exercise caution when taking this medicine.
Those with a history of radiation therapy should also be cautious.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet to help manage the side effects and support your general health during cancer treatment.
Regular gentle exercise, such as walking or yoga, can help boost energy levels and manage fatigue associated with this medicine.
Avoiding exposure to sunlight or wearing protective clothing outdoors can help prevent skin reactions to the medicine.
Frequently asked questions
Is Melphalan a type of chemotherapy?
Yes, Melphalan is indeed a type of chemotherapy. It belongs to a group of medicines called alkylating agents, which are used to manage certain types of cancer.
Does Melphalan have any effect on sleep?
Melphalan is not associated with affecting sleep. However, it can cause fatigue and weakness which could indirectly affect a patient's sleep patterns. If you experience any persistent sleep disturbances while taking this medicine, please consult your doctor.
Will Melphalan affect fertility?
Yes, Melphalan might affect fertility in both men and women. It may cause infertility which could potentially be permanent. If you are planning to have children in the future, it is important to discuss this with your doctor before commencing treatment with this medicine.
How long does it take for Melphalan to start working?
The time for Melphalan to start showing its effects can vary from person to person and depends on the type and stage of cancer being managed. Your doctor will monitor your progress regularly during the treatment.
What is the best time to take Melphalan?
The best time to take Melphalan depends on your treatment plan and should be determined by your doctor. Always follow the schedule provided by your doctor faithfully.
Can I buy Melphalan over the counter?
No, Melphalan is a prescription medicine and can only be obtained with a doctor's prescription due to potential severe side effects and the need for close monitoring during treatment.
Is Melphalan a steroid?
No, Melphalan is not a steroid. It is a type of chemotherapy medicine known as an alkylating agent.
Subscribe
Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.
Download Truemeds
Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Contact Us
Our customer representative team is available 7 days a week from 9 am - 9 pm.
v3.3.6
2024 - Truemeds | All rights reservedOur Payment Partners
