Mebeverine
Uses of Mebeverine
Mebeverine is used to manage symptoms associated with irritable bowel syndrome (IBS). It belongs to the class of medicines known as musculotropic antispasmodics.
In addition to IBS, Mebeverine may also be used for other conditions involving intestinal spasms, such as chronic irritable colon, spastic constipation, mucous colitis, and spastic colitis.
Side effects of Mebeverine
Nausea
Headache
Dizziness
Insomnia
Allergic skin reactions
How Mebeverine works
Mebeverine is a musculotropic antispasmodic agent.
It performs its function by directly relaxing the smooth muscles in the gut, which helps in relieving painful spasms. This muscle relaxation is achieved through two key mechanisms.
By blocking voltage-operated calcium channels, it prevents calcium influx and smooth muscle contraction.
By antagonising muscarinic acetylcholine receptors, it reduces cholinergic transmission and intestinal motility.
Certified content
Written By
BDS, MDS
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
Mebeverine is available for oral administration via the following forms: immediate-release tablets, sustained-release capsules, and granules for oral suspension.
Age And Dose Restrictions
Mebeverine is intended for use in adults and adolescents above 12 years of age. The suitable dose would be advised by the doctor.
Contraindications
Mebeverine is contraindicated in individuals with a known hypersensitivity to Mebeverine or any of its components.
Patients with porphyria, a group of rare genetic disorders that affect the nervous system, should not use this medicine.
Other Medications To Avoid With This Medicine
Mebeverine may interact with antimuscarinic medicines (such as atropine and scopolamine), opioids (such as codeine and morphine), antifungals (like ketoconazole), and medications for tuberculosis (such as rifampicin).
Overdose And Missed Dose
An overdose of Mebeverine may lead to symptoms like severe headache, vomiting, and dizziness. If you observe these symptoms, inform your doctor immediately.
If you forget to take a dose of this medicine, take it as soon as you remember. However, do not double the dose if it is close to the time for the next dose.
Management Of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking ample water can help ease dry mouth.
Relaxation techniques like deep breathing exercises can help manage dizziness and insomnia.
Use In Driving And Operating Machinery
Mebeverine may cause side effects such as dizziness or sleepiness. If you experience these after taking the medicine, avoid driving or operating heavy machinery until you feel well again.
Use In Pregnancy And Lactation
Mebeverine should be used during pregnancy and lactation only if prescribed by your doctor.
Caution In Other Conditions
Patients with significant bladder outflow obstruction, angle-closure glaucoma, and myasthenia gravis (weakness and rapid fatigue of voluntary muscles) should use this medicine carefully, as it may exacerbate these conditions.
Special Dietary And Lifestyle Recommendation
Maintain a balanced diet with plenty of fruits, vegetables, and whole grains.
Regular physical activity can help relieve stress and improve digestion.
Limit intake of gas-producing foods like beans, broccoli, and cabbage, which may worsen IBS symptoms.
Avoid food triggers, which can vary from person to person but may include dairy products, caffeine, and alcohol.
Frequently asked questions
Is Mebeverine a steroid?
No, Mebeverine is not a steroid. It belongs to the class of antispasmodic medications, specifically known as musculotropic antispasmodics.
Does Mebeverine have any effect on sleep?
Mebeverine has been reported to cause insomnia in some cases, but this side effect is relatively uncommon. Always consult your doctor if you experience unexpected or severe side effects.
Will Mebeverine affect fertility?
There is no evidence to suggest that Mebeverine affects fertility in men or women. However, if you have any concerns or experience any issues, you should discuss them with your doctor.
Is it safe to take Mebeverine daily?
Mebeverine should be taken in the dosage and duration as prescribed by your doctor and used according to their instructions.
How much time does Mebeverine take to work?
The exact time for Mebeverine to start working can vary between different individuals, but generally, it starts acting within a few hours of administration.
What is the best time to take Mebeverine?
The best time to take Mebeverine is approximately 20 minutes before meals, as advised by your doctor.
Is Mebeverine available over the counter, or do I need a prescription?
Mebeverine usually requires a prescription and is not typically available over the counter.
Mebeverine in other salts
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