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Mebendazole

Uses of Mebendazole

  • Mebendazole is principally used to manage various parasitic worm infections in humans. It belongs to the anthelmintic class of medicines.

  • The medicine can be used to handle infections caused by Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale and Necator americanus (hookworms), Strongyloides stercoralis (threadworm), and Taenia spp. (tapeworms).

Side effects of Mebendazole

  • Common side effects of this medication include:

  • Abdominal pain

  • Diarrhoea

  • Flatulence

  • Nausea

  • Vomiting

How Mebendazole works

  • Mebendazole is an anthelmintic medicine, a type of medication designed to kill parasitic worms.

  • It works by specifically stopping the development of microtubules in parasitic worms. These microtubules are like tiny tubes within the cell that help the worm take in glucose, a type of sugar that gives them energy.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 Years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Mebendazole is available for oral administration in the form of (tablets).

Age and Dose Restrictions

  • Mebendazole is intended for both adults and children who are 2 years of age and older.

Contraindications

  • Mebendazole is contraindicated in patients with a known hypersensitivity to it or any of its excipients.

  • It should also be used with caution in patients with hepatic impairment or bone marrow depression.

Other Medications to Avoid

  • Mebendazole may interact with histamine H2 receptor antagonists (such as cimetidine), anti-infective agents (like metronidazole), antiepileptic agents (such as phenytoin), and bronchodilators (like theophylline).

Overdose and Missed Dose

  • Overdose symptoms of Mebendazole can include nausea, vomiting, diarrhoea, and abdominal pain. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience upset stomach or nausea, try taking Mebendazole with food.

  • Drink plenty of water to manage minor side effects such as flatulence and diarrhoea.

Use in Driving and Operating Machinery

  • There is no known effect of Mebendazole on the ability to drive or operate machinery. However, if you feel dizzy or fatigued after taking this medicine, avoid such activities.

Use in Pregnancy and Lactation

  • Mebendazole should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. It may pass into breast milk, but no adverse effects on infants have been seen. Consult your doctor before using during pregnancy or breastfeeding.

Caution in Other Conditions

  • Caution is advised when using Mebendazole in patients with liver disease as it is mainly metabolised by the liver.

  • Caution is also advised for patients with bone marrow depression, as some severe side effects may worsen this condition.

Special Dietary and Lifestyle Recommendations

  • Maintaining a balanced diet can help strengthen the immune system to fight off parasitic infections.

  • Regular hand washing, especially before meals and after using the toilet, is essential to prevent re-infection.

  • Avoid walking barefoot in areas where soil-transmitted helminth infections are endemic.

  • Ensure that your living space is clean and hygienic to prevent worm infections from spreading.

Frequently asked questions

No, Mebendazole is not a steroid. It is an anthelmintic medicine that belongs to the benzimidazole class.

Mebendazole does not generally affect sleep. However, individual experiences can vary. If you experience any unusual sleep-related side effects after taking this medication, consult your doctor.

There is no mentioned effect of Mebendazole on fertility in the available literature. If you have concerns about fertility-related issues, it is advisable to discuss this with your doctor.

The duration of treatment with Mebendazole varies depending on the type and severity of the worm infection being treated. Always follow your doctor's instructions regarding the duration of treatment.

The safety of daily use of Mebendazole depends on the type and severity of the worm infection being treated. It should be taken exactly as directed by your doctor.

The worms usually die within a few days after Mebendazole administration. However, it may take up to 3 weeks for symptoms to completely resolve.

Mebendazole is a prescription medication in most countries. It requires a valid prescription from a doctor.

Terms & Conditions

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