Levetiracetam
ANTIEPILEPTICUses of Levetiracetam
- Levetiracetam helps treat Epilepsy/Seizures.
- Levetiracetam helps control various types of seizures, including partial-onset seizures (which start in one part of the brain), myoclonic seizures (brief, shock-like muscle jerks), and tonic-clonic seizures (involving loss of consciousness and muscle stiffening and jerking).
Side effects of Levetiracetam
- Sleepiness
- Dizziness
- Fatigue
- Headache
- Decreased appetite
- Behavioral changes
- Aggressive behavior
- Irritation Agitation
- Nasal congestion (stuffy nose)
- Infection
How Levetiracetam works
- Levetiracetam falls under the Antiepileptic category.
- It works by affecting the transmission of electrical signals in the brain. It binds to a specific protein (SV2A) on the surface of nerve cells, which is involved in the release of neurotransmitters.
- This interaction helps stabilize abnormal electrical activity in the brain and reduces the frequency and severity of seizures.
- Additionally, levetiracetam may modulate certain ion channels and neurotransmitter systems, contributing to its overall anticonvulsant effects.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Levetiracetam can be taken orally (tablets), and intravenously (injection).
Age and Dose Restrictions
- Levetiracetam can be taken by adults and children with appropriate dosage.
Contraindications
- Levetiracetam is contraindicated if you have known allergy to Levetiracetam or any of its excipients.
- It is also contraindicated in patients with severe kidney impairment.
Other Medications to Avoid With This Medicine
- Avoid taking anticoagulants (warfarin), other antiepileptics (Phenytoin or Carbamazepine, and CNS Depressants (benzodiazepines or opioids). The concomitant use may lower the effectiveness of Levetiracetam and increase the risk of side effects.
Overdose and Missed Dose
- Overdose can cause drowsiness, agitation, aggression, or decreased consciousness. Immediate medical attention is necessary.
- If a dose is missed, it should be taken as soon as remembered. If it’s almost time for the next dose, skip the missed dose. Do not double up to make up for it.
Management of Side Effects
- To combat drowsiness and fatigue, adjust the dosage or timing to take this medicine.
Use In Driving And Operating Machinery
- It's crucial to evaluate individual tolerance to the medication before engaging in activities requiring full alertness, such as driving or operating machinery. If any impairments are noted, it is advisable to avoid such tasks.
Use in Pregnancy and Lactation
- Levetiracetam should be cautiously used during pregnancy and breastfeeding.
Caution in Other Conditions
- Caution is advised in the patients with kidney Impairment and psychiatric disorders.
Special Dietary and Lifestyle Recommendations
- To maintain stable medicine levels and avoid gastrointestinal upset, take Levetiracetam with or without food consistently.
- Adequate hydration can support kidney function, which is important for the metabolism and excretion of the drug.
- Alcohol can intensify side effects such as drowsiness and dizziness, so it’s best to limit or avoid alcohol consumption while on Levetiracetam.
Frequently asked questions
1. Is Levetiracetam safe to use during pregnancy?
No, using it during pregnancy may not be safe. Although there is a lack of information in human research, there is evidence from animal studies that this is harmful to a fetus. Your doctor will consider the risks and benefits before a prescription is given. Please consult your physician.
2. How much time does it take to work?
Within 1 to 2 hours, you must experience the benefit of Levetiracetam.
3. Is it safe for breastfeeding mothers?
No, it's likely unsafe to take Levetiracetam during breastfeeding. According to human data, the medicine may enter the breast milk and harm the unborn baby.
4. Which medications should be avoided while using Levetiracetam?
It is not recommended to use any anti-HIV medications (amprenavir, ritonavir), medications for anxiety or seizures (carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone), medications for acid reflux (cimetidine), alcoholism treatment (disulfiram), TB treatment (rifampin), Parkinson's disease treatment (levodopa), and asthma (theophylline). Before using any prescription or over-the-counter medications, you must consult your doctor.
5. What warnings and precautions should I take while taking Levetiracetam?
Do not use Levetiracetam if you have an allergic reaction (hypersensitivity) to any of its components. Do not take Levetiracetam if you consume multivitamins, multi-mineral, or other herbal supplements and alcohol. Due to a possible interaction, Levetiracetam may increase the chance of serious adverse effects. We recommend that you consult a doctor as soon as possible.
6. Should I stop taking Levetiracetam if I feel healthy?
No, please do not stop taking Levetiracetam without first consulting your doctor. There is a chance that symptoms may return if the medicine is suddenly stopped.
7. Does taking Levetiracetam cause weight gain?
No, it is unlikely to cause weight gain. You should consult a doctor if you have any unusual symptoms while taking
8. Does Levetiracetam a habit-forming medicine?
No, the use of Levetiracetam will not lead to the development of any habitual actions. There have been no reports that withdrawal symptoms may appear when it is stopped. It is possible for people in this situation to develop a psychological dependence on the medication if they continue to use it.
9. Does taking Levetiracetam cause nausea and vomiting?
Yes, using this medicine can cause you to feel nausea and vomiting. If you vomit, drink water or other liquids continuously in small quantities. If you observe symptoms of dehydration, such as persistent vomiting, dark urine with a strong odour, or infrequent urination, consult your doctor. Without first consulting a doctor, avoid taking any additional medications.
10. Is it safe to drink alcohol while taking Levetiracetam?
No, avoid consuming alcohol while taking Levetiracetam because it could increase dizziness and drowsiness.
11. Does Levetiracetam affect fertility?
No, it is unlikely to affect fertility in either men or women. However, there is currently insufficient evidence to justify any clear conclusion. Consult your doctor for the most accurate information.
12. Is it safe for patients with kidney disease to use Levetiracetam?
Yes, it should be used with precaution, specifically if you have a history of kidney disorders or problems. Some patients may need a dosage modification of Levetiracetam. If you have any problems, you should consult your doctor.
13. Is it safe for patients with liver disease to use Levetiracetam?
Yes, it should be used with precaution, specifically if you have a history of liver disorders or problems. Some patients may need a dosage modification of Levetiracetam. If you have any problems, you should consult your doctor.
14. Does taking Levetiracetam cause dizziness?
Yes, it may cause dizziness. While using Levetiracetam, it is recommended that you should not drive or operate heavy machinery. Relaxing until you feel better if you are experiencing sleep or dizziness is suggested.
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