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Kanamycin

Uses of Kanamycin

  • The primary use of Kanamycin is to manage serious bacterial infections. It belongs to the group of aminoglycoside antibiotics.

  • The medicine is also used in cases of urinary tract infections, respiratory tract infections, meningitis, septicemia, bone and joint infections, and skin and soft tissue infections.

Side effects of Kanamycin

  • Nausea and vomiting

  • Diarrhoea

  • Increased risk of kidney damage

  • Hearing loss (ototoxicity)

  • Allergic reactions

How Kanamycin works

  • Kanamycin is an aminoglycoside antibiotic.

  • It acts by binding to the 30S subunit of the bacterial ribosome, which disrupts the initiation process of protein synthesis, leading to the production of defective proteins.

  • The accumulation of these faulty proteins interferes with vital cellular processes, ultimately leading to the death of the susceptible bacteria.

  • Kanamycin's action is particularly potent against aerobic gram-negative bacteria, making it an effective weapon against many harmful infections caused by these types of bacteria.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer|

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Kanamycin is available as an injectable solution, which is administered either through the intramuscular or intravenous route.

  • Additionally, Kanamycin can be taken orally in the form of capsules.

Age and Dose Restrictions

  • This medicine is meant for use by both adults and children. However, specific age restrictions may apply, depending on the severity of the infection and the patient's overall health condition.

Contraindications

  • This medicine is contraindicated in patients with known allergies to aminoglycosides.

  • It is also contraindicated in individuals with severe renal, vestibular and auditory impairment.

Other Medications to Avoid

  • Kanamycin may interact with neuromuscular blockers (such as vecuronium and pancuronium), loop diuretics (including furosemide), and certain anaesthetics (like propofol).

Overdose and Missed Dose

  • An overdose of Kanamycin may lead to serious complications such as nephrotoxicity (kidney damage) or ototoxicity (hearing loss). Immediate medical attention is necessary if an overdose is suspected.

  • If a dose of Kanamycin is missed, it should be taken as soon as possible unless it is nearly time for the next dose. In such cases, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Adjusting the timing of medication may help manage some side effects.

  • Ensuring adequate hydration can help reduce the risk of nephrotoxicity.

Use in Driving and Operating Machinery

  • Kanamycin may cause dizziness or drowsiness. It is advised to avoid driving or operating heavy machinery if these symptoms are experienced after administration.

Use in Pregnancy and Lactation

  • Kanamycin is generally not recommended during pregnancy and breastfeeding due to potential risks to the fetus and infant. Consulting a doctor before using this medication during pregnancy or lactation is crucial.

Caution in Other Conditions

  • Patients with existing kidney diseases should use Kanamycin with caution due to its potential nephrotoxic effects.

  • Individuals with hearing problems should also be cautious, as Kanamycin can exacerbate ototoxicity.

Special Dietary and Lifestyle Recommendations

  • Maintaining adequate hydration is crucial while using Kanamycin to help mitigate potential kidney damage.

  • Monitoring salt intake may be advisable, especially for patients prone to oedema or those with hypertension.

  • Regular hearing checks could be beneficial for long-term users of Kanamycin to detect any early signs of ototoxicity.

  • Engaging in low-impact physical activities like walking or swimming can support overall health without overstraining the body, especially for those managing severe infections.

Frequently asked questions

While some antibiotics can interfere with the effectiveness of birth control pills, there is no specific information available suggesting that Kanamycin does. However, if you are on birth control, it is better to consult your doctor to be sure.

There is no mention in the provided references about an interaction between alcohol and Kanamycin. However, as alcohol can potentially exacerbate the side effects of many medicines, it is advisable to consult your doctor before consuming alcohol while taking this medicine.

Taking a double dose of Kanamycin may increase your risk of experiencing side effects such as nausea, vomiting or kidney damage. If you accidentally take a double dose, consult your doctor immediately.

There is no evidence to suggest that Kanamycin causes changes in mood or behaviour. However, if you notice any changes in your mood or behaviour while taking this medicine, consult your doctor immediately.

There are no natural alternatives that have been proven to be as effective as Kanamycin for treating bacterial infections.

There is no known relationship between shellfish allergies and an increased risk of allergic reaction to Kanamycin. However, if you have any kind of allergy, inform your doctor before starting this medication.

Although there are no known interactions between vitamins and Kanamycin mentioned in the provided references, it is always a good idea to inform your doctor about any other medications or supplements you are taking.

Terms & Conditions

Available medicines for KANAMYCIN
Efficin 750 MG Injection 10 ML
Efficin 750 MG Injection 10 ML
Lupin Ltd
Pack of 10 ML
₹27.88
MRP ₹34.00
18.00% OFF
Efficin 1000 MG Injection 1
Efficin 1000 MG Injection 1
Lupin Ltd
Pack of 1 Units
₹29.19
MRP ₹35.60
18.00% OFF
Kanamac 1000 Injection 1
Kanamac 1000 Injection 1
Macleods Pharmaceuticals Pvt.ltd
Pack of 1 UNITS
₹35.99
MRP ₹43.89
18.00% OFF
Kancin 1000 MG Injection 1
Kancin 1000 MG Injection 1
Alembic Ltd
Pack of 1 Units
₹25.63
MRP ₹31.25
18.00% OFF
Kanamac 500 Injection 1
Kanamac 500 Injection 1
Macleods Pharmaceuticals Pvt.ltd
Pack of 1 Units
₹19.53
MRP ₹23.82
18.00% OFF
Efficin 500 MG Injection 1
Efficin 500 MG Injection 1
Lupin Ltd
Pack of 1 Units
₹13.13
MRP ₹16.01
18.00% OFF
Kanamac 750 Injection 1
Kanamac 750 Injection 1
Macleods Pharmaceuticals Pvt.ltd
Pack of 1 UNITS
₹33.54
MRP ₹40.90
18.00% OFF

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