Iohexol
Uses of Iohexol
The main use of Iohexol is to enhance imaging in various radiological procedures such as X-rays, computed tomography (CT) scans and angiography. It belongs to the group of iodinated contrast media.
It is also indicated for diagnostic imaging of different parts of the body, including the brain, spine, heart, blood vessels, gastrointestinal tract and joints. Other procedures where Iohexol is used include myelography, arthrography, hysterosalpingography, intravenous pyelography and herniography.
Side effects of Iohexol
Nausea
Vomiting
Headache
Warmth at the injection site
Itching
How Iohexol works
Iohexol is a non-ionic, water-soluble, iodinated contrast medium. It helps enhance imaging in various radiological procedures. The iodine component in Iohexol has a high atomic number and is capable of attenuating X-rays. When Iohexol is administered into the body, it temporarily increases the density of the tissues or fluids it reaches. This enhances the contrast between different structures during imaging.
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Doctor of Medicine
Expert Advice
Dosage Forms Available
Iohexol is available in various strengths for infusion (intravascular injection) and for oral administration (solution).
Age and Dose Restrictions
This medicine is recommended for adults and children of age above 12 years.
Contraindications
Iohexol is contraindicated in patients with known severe hypersensitivity to Iohexol or other iodinated contrast media. Additionally, it should not be used in patients with manifest thyrotoxicosis due to the risk of thyroid storm.
Other Medications to Avoid
Iohexol may interact with antidiabetic agents (such as metformin), cardiovascular medicines (like atenolol), anti-inflammatory medicines (such as ibuprofen and paracetamol), kidney-damaging medications (like tobramycin and amikacin), and immune response modifiers (such as daclizumab and basiliximab).
Overdose and Missed Dose
Overdosing with Iohexol although highly unlikely as it is administered by a healthcare professional may result in exaggerated side effects such as nausea, vomiting, and dizziness. In case of a suspected overdose, contact your doctor promptly for guidance.
If you miss a scheduled dose of Iohexol, consult your doctor for instructions. Do not attempt to make up for the missed dose without medical advice.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage side effects such as nausea and vomiting.
Taking rest may help alleviate dizziness or headache.
Applying a cold compress to the injection site might help manage discomfort or pain.
Use in Driving and Operating Machinery
There might be transient side effects such as dizziness or blurred vision after taking Iohexol, which may affect one’s ability to drive or operate machinery. It is advisable to avoid such tasks until these effects subside.
Use in Pregnancy and Lactation
Iohexol should only be used during pregnancy and lactation if needed and the potential benefits outweigh the potential risks. It is advised to consult a doctor before its use during these conditions.
Caution in Other Conditions
Patients with renal impairment, diabetes, multiple myeloma, or cardiovascular disease should exercise caution when taking Iohexol. These underlying conditions may increase the risk of adverse reactions.
Special Dietary and Lifestyle Recommendations
Ensure proper hydration before and after the procedure to help flush the contrast medium from the body and reduce the risk of kidney damage.
Regular monitoring of blood pressure and blood glucose levels would be beneficial for those with cardiovascular disease or diabetes respectively, while undergoing a procedure involving Iohexol.
Frequently asked questions
Is Iohexol a steroid?
No, Iohexol is not a steroid. It is a non-ionic, water-soluble iodinated contrast medium.
Can Iohexol affect my mood?
Iohexol is not associated with affecting mood. However, if you experience any unusual changes in your mood after receiving Iohexol, please consult your doctor immediately.
Is Iohexol an over-the-counter medicine?
No, Iohexol is not an over-the-counter medicine. It is used in specific diagnostic procedures and must be administered by a doctor.
Is Iohexol to be administered only in hospital settings?
Yes, Iohexol should only be administered by a doctor in radiological procedures in appropriate medical settings.
Does Iohexol have any effect on menstruation?
Iohexol is not associated with affecting the menstrual cycle. However, if you notice any changes in your menstrual cycle after receiving Iohexol, please consult your doctor.
Can I take natural alternatives instead of Iohexol for a diagnostic procedure?
No, natural alternatives cannot substitute the use of Iohexol in diagnostic imaging procedures.
How does Iohexol leave the body?
Iohexol is mainly eliminated from the body through the kidneys within 24 hours after administration.
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