Insulin Lispro
Uses of Insulin Lispro
Insulin Lispro is primarily utilised to manage both type 1 and type 2 diabetes mellitus in adults and children and belongs to the category of rapid-acting insulin analogues.
It is often used alongside longer-acting insulins or oral diabetes medicines, to allow optimal blood sugar control. Its fast-acting property makes it especially useful in managing post-meal blood sugar spikes.
Side effects of Insulin Lispro
Hypoglycaemia (low blood sugar)
Injection site reactions
Weight gain
How Insulin Lispro works
Insulin Lispro is a fast-acting insulin analogue.
It works by copying the actions of naturally produced insulin in the human body. It helps control blood sugar levels by facilitating the uptake of glucose into cells, especially in muscle and fat tissues.
The result of this process is a decrease in blood sugar levels, which helps manage diabetes effectively.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Insulin Lispro is available in various dosage formulations, including vials, prefilled pens, and cartridges.
This medication is typically administered by a subcutaneous injection, which means it is injected under the skin using a syringe, an insulin pen, or an insulin pump.
Age and Dose Restrictions
This medicine is intended for use in both adults and children (above 3 years old) to manage type 1 diabetes.
This medication should not be used to manage type 2 diabetes in a child of any age. However, it can be used by adults for type 2 diabetes under a doctor's supervision.
Contraindications
Insulin Lispro is not recommended for use in patients who have hypersensitivity to any of its components.
It is also contraindicated in patients who have hypoglycaemia (low blood glucose levels).
Other Medications to Avoid
Insulin Lispro may interact with oral diabetes medications (such as metformin and sulphonylureas), corticosteroids (like prednisone and cortisone), thyroid medications (like levothyroxine and liothyronine), and beta-blockers (for example, atenolol and propranolol).
Before starting any prescription or over-the-counter medications, it is crucial to consult a doctor to avoid any potential interaction.
Overdose and Missed Dose
An overdose of the medicine may result in hypoglycaemia, marked by symptoms like shakiness, dizziness, sweating, and confusion. If you observe these symptoms, inform your doctor immediately.
If you forget to administer a dose of this medicine, do it as soon as you remember. However, avoid repeating the dose.
Management of Side Effects
Most side effects of Insulin Lispro are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For minor injection site reactions such as pain, swelling, or itching, rotating injection sites can help minimise these reactions.
Use in Driving and Operating Machinery
As Insulin Lispro can potentially cause hypoglycaemia which may result in dizziness or confusion, it could impair your ability to drive or operate heavy machinery. It is therefore recommended to avoid engaging in such activities after administering the medicine.
Use in Pregnancy and Lactation
It should be used during pregnancy and whilst breastfeeding only if clearly needed and under close medical supervision. It is advised to consult a doctor before using this medicine during these periods.
Caution in Other Conditions
Patients with kidney or liver problems should exercise caution when using Insulin Lispro as they may require dose adjustments.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet that is low in sugars and refined carbohydrates to manage blood sugar levels effectively.
Regular monitoring of blood sugar levels is crucial in managing diabetes.
Engage in regular physical activity as directed by your doctor to aid in maintaining healthy blood sugar levels.
Smoking should be avoided as it increases the risk of diabetes-related complications.
Frequently asked questions
Is Insulin Lispro a kind of natural insulin?
No, this is a man-made form of insulin. It is known as an insulin analogue and works similarly to natural human insulin, helping control blood sugar levels.
Does Insulin Lispro have any impact on one's mood?
It primarily manages blood glucose levels, which indirectly can influence your mood. Inconsistent blood sugar levels may lead to mood swings. However, it does not directly affect one's mood.
Can Insulin Lispro influence my menstrual cycle?
The medicine works to manage blood glucose levels in the body and does not directly affect the menstrual cycle. However, poorly managed diabetes can impact the menstrual cycle, so it's important to use it as prescribed by your doctor.
Are there any natural alternatives to Insulin Lispro?
There are no natural alternatives that can substitute the effects of Insulin Lispro. Managing diabetes requires medical supervision and appropriate medication. Lifestyle changes like a healthy diet and regular exercise can complement your treatment but cannot replace medication.
If I am allergic to certain types of insulin, could I be allergic to Insulin Lispro?
Allergies vary from person to person. If you have had allergic reactions to other types of insulin, consult your doctor before using this medicine.
How long does one dose of Insulin Lispro stay active in the body compared to regular human insulin?
It has a faster onset and shorter duration of action compared to regular human insulin, making it ideal for managing blood sugar levels around mealtimes.
Is there any particular timing for administering Insulin Lispro?
It is typically administered around meal times due to its rapid onset of action. However, it's important to follow your doctor's instructions regarding when and how often to administer the medicine.
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