Haloperidol + Trihexyphenidyl

Dosage Forms Available

• Haloperidol + Trihexyphenidyl is available in the form of tablets and oral solutions, which are to be taken orally.

Age and Dose Restrictions

• This medication is typically recommended for adults and children over the age of 12 years.

Contraindications

• Haloperidol + Trihexyphenidyl should not be given to patients suffering from severe central nervous system depression.
• It is also contraindicated in patients with a history of QT prolongation or other heart rhythm disorders and in those diagnosed with Parkinson's disease.

Other Medications to Avoid

• This combination may interact with other anticholinergics (such as benztropine and oxybutynin), antidepressants (such as fluoxetine and paroxetine), antihistamines (such as diphenhydramine and levocetirizine), antihypertensives (such as propranolol and atenolol), and Parkinson's disease medications (such as levodopa and carbidopa).

Overdose and Missed Dose

• Overdose symptoms can include severe drowsiness, confusion, agitation, irregular heartbeat, and muscle stiffness. Seek emergency medical attention immediately if you suspect an overdose.
• If a dose is missed, take the medicine as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage side effects like dry mouth and constipation.
• Rest and avoiding sudden movements can help manage dizziness.
• Make sure to take this medicine with food to help reduce any potential stomach upset.

Use in Driving and Operating Machinery

• Haloperidol + Trihexyphenidyl may cause drowsiness and dizziness. If affected, you should not drive or operate machinery until these symptoms subside.

Use in Pregnancy and Lactation

• The safety of Haloperidol + Trihexyphenidyl during pregnancy has not been established. It is advised to consult a doctor before using this combination during pregnancy or breastfeeding.

Caution in Other Conditions

• Patients with a history of seizures, heart problems, liver or kidney disease, glaucoma, or urinary retention should use Haloperidol + Trihexyphenidyl with caution.

Special Dietary and Lifestyle Recommendations

• Practising good sleep hygiene can also help manage any potential sleep disturbances caused by this medication.
• Regular, light physical activity like walking or stretching can be beneficial in managing restlessness that could potentially be caused by this medicine.