Gemifloxacin
Uses of Gemifloxacin
Gemifloxacin is primarily used for managing bacterial infections, particularly those affecting the respiratory tract. It belongs to the group of fluoroquinolone antibiotics.
This medicine is also indicated for managing acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, and acute bacterial sinusitis.
Side effects of Gemifloxacin
Diarrhoea
Skin rash
Nausea
Headache
Dizziness
Abdominal pain
How Gemifloxacin works
Gemifloxacin is a synthetic antibacterial agent, which belongs to the fluoroquinolone class of antibiotics.
It works by inhibiting two key enzymes in bacteria: DNA gyrase and topoisomerase IV. These enzymes are crucial for bacterial DNA replication, transcription, repair, and recombination, which are all necessary processes that bacteria need to grow and multiply. When Gemifloxacin interferes with these processes, it stops the growth and replication of bacteria, leading to their death. This effectively helps in controlling and managing bacterial infections.
Certified content
Written By
Doctor of Medicine
Reviewed By
BAMS, APG, PG
Expert Advice
Dosage Forms Available
Gemifloxacin is available in tablet form for oral administration.
Age and Dose Restrictions
Gemifloxacin is intended for use in adults only. The safety and efficacy of this medication have not been well-established in children.
Contraindications
Gemifloxacin is contraindicated in patients with a known hypersensitivity to it or other quinolones.
Other Medications to Avoid
Gemifloxacin may interact with antacids and other medicines containing metal cations such as iron and zinc (e.g., aluminium hydroxide, magnesium hydroxide, and calcium carbonate) and anticoagulants (like warfarin and probenecid).
Overdose and Missed Dose
In case of an overdose of Gemifloxacin, seek immediate medical help. Overdose can result in severe nausea, vomiting, diarrhoea, or dizziness, which need to be managed by health professionals.
If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule.
Management of Side Effects
Most side effects induced by Gemifloxacin are temporary and generally harmless and resolve upon discontinuation of this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage diarrhoea caused by this medicine.
For managing nausea or vomiting, it can be helpful to take medication with food.
Use in Driving and Operating Machinery
This medicine may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy or sleepy after taking this medicine.
Use in Pregnancy and Lactation
Gemifloxacin is not recommended in pregnancy unless recommended by your doctor. It may cause harm to the foetus based on animal data. In the case of breastfeeding, it is not known if this medication is excreted in human milk. Always consult your doctor before using this medicine during pregnancy and breastfeeding.
Caution in Other Conditions
Patients with myasthenia gravis (muscle weakness and fatigue) should exercise caution when taking Gemifloxacin due to an increased risk of muscle weakness.
Patients with renal impairment should use Gemifloxacin with caution, with dose adjustment for those with creatinine clearance of <40 mL/min.
Special Dietary and Lifestyle Recommendations
Avoid exposure to sunlight or tanning beds as Gemifloxacin can make you susceptible to sunburns. Wear protective clothing and use sunscreen with an SPF of 30 or higher when you are outdoors.
Maintain adequate hydration by drinking plenty of fluids. Gemifloxacin can potentially increase the risk of crystalluria (crystals in the urine), which may lead to kidney damage if not managed properly.
Frequently asked questions
Is Gemifloxacin a steroid?
No, Gemifloxacin is not a steroid. It is an antibacterial agent belonging to the fluoroquinolone class of antibiotics.
Does Gemifloxacin have any effect on sleep?
There is no specific mention of Gemifloxacin affecting sleep, but consult your doctor if you experience sleep disturbances.
Will Gemifloxacin affect fertility?
There is no specific mention of Gemifloxacin affecting fertility, but consult your doctor if you’re planning a pregnancy or have fertility concerns.
Is it safe to take Gemifloxacin daily?
Gemifloxacin should be taken as prescribed by your doctor. The duration and frequency of use depend on the type and severity of the condition.
How much time does Gemifloxacin take to work?
The effectiveness of Gemifloxacin varies with the infection type and severity; consult your doctor for specific information on how long it may take to see results.
What is the best time to take Gemifloxacin?
Gemifloxacin can generally be taken at any time of the day, but it should be taken at least 2 hours before or 3 hours after taking any medications containing multivalent cations such as iron, zinc, or antacids.
Is Gemifloxacin available over the counter, or do I need a prescription?
Gemifloxacin is an antibiotic medication and typically requires a doctor's prescription. It is usually not available for purchase over the counter.
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