Gabapentin + Mecobalamin
Uses of Gabapentin + Mecobalamin
Gabapentin + Mecobalamin is primarily used for managing neuropathic pain and belongs to the group of anticonvulsant and vitamin B12 medicines
This combination medicine is also prescribed for conditions like diabetic neuropathy, postherpetic neuralgia, and other types of neuropathic pain like trigeminal neuralgia, complex regional pain syndrome, or pain related to spinal cord injuries.
Side effects of Gabapentin + Mecobalamin
Drowsiness
Dizziness
Nausea or vomiting
Dry mouth
Blurred vision
How Gabapentin + Mecobalamin works
Gabapentin + Mecobalamin is a anticonvulsant medication.
Gabapentin, the anticonvulsant, works by sticking to specific spots on calcium channels in the brain. This action helps lessen the release of neurotransmitters that can cause seizures and neuropathic pain. It also influences the activity of GABA (gamma-aminobutyric acid), a substance which helps control nerve signalling.
Mecobalamin, a form of Vitamin B12, plays a significant role in keeping the nervous system healthy. It aids the development of the myelin sheath, a cover that insulates and guards nerve fibres. This promotes proper nerve function and decreases pain signals.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Gabapentin + Mecobalamin is available for use as tablets and capsules.
These oral solutions are administered by taking them through the mouth.
Age and Dose Restrictions
This medicine is meant for adults.
Contraindications
Gabapentin + Mecobalamin is contraindicated in patients with severe kidney impairment.
It is also contraindicated in individuals who have a known allergy to gabapentin or mecobalamin, or any of the inactive ingredients in the formulation.
Overdose and Missed Dose
An overdose of Gabapentin + Mecobalamin might lead to symptoms such as severe dizziness, double vision, slurred speech, and loss of coordination. If you suspect an overdose, it is crucial to seek immediate medical attention.
If you miss a dose of this medicine, take it as soon as you remember unless it is almost time for your next scheduled dose. Do not take two doses at one time to make up for a missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For dizziness or drowsiness, try taking the medicine at a time when you can rest and recover after administration.
If experiencing dry mouth, increase your intake of water to help alleviate discomfort.
Caution in Other Conditions
Caution is advised when using Gabapentin + Mecobalamin in patients with renal impairment. Adjustments in dosage might be necessary to avoid build-up of the medication due to reduced kidney function.
Special Dietary and Lifestyle Recommendations
For individuals managing neuropathic pain like diabetic neuropathy, maintaining a balanced diet rich in vitamins and minerals can aid nerve health. Include foods high in B vitamins (meat, eggs, nuts), magnesium (leafy greens, nuts), and antioxidants (berries, nuts).
Regular non-strenuous exercise such as walking can increase blood flow to peripheral nerves and aid overall nerve health.
It is beneficial to avoid smoking and limit alcohol consumption as these can worsen neuropathic pain.
Managing blood sugar levels effectively through diet is crucial for those with diabetic neuropathy. Monitor carbohydrate intake and consider consulting a nutritionist for personalised advice.
Frequently asked questions
Can Gabapentin + Mecobalamin cause allergic reactions?
Yes, Gabapentin + Mecobalamin can cause allergic reactions in some individuals. If symptoms such as skin rash, itching, swelling of the face, tongue or throat, severe dizziness or difficulty in breathing occur, seek immediate medical help.
Is Gabapentin + Mecobalamin safe during pregnancy and breastfeeding?
The use of Gabapentin + Mecobalamin during pregnancy and breastfeeding should be under the supervision of a doctor. It should only be used if the potential benefits outweigh the risks.
Can I stop taking Gabapentin + Mecobalamin abruptly?
No, you should not stop taking Gabapentin + Mecobalamin abruptly as it may lead to withdrawal symptoms or worsening of your condition. Always consult your doctor before altering the dosage or stopping the medicine.
Is Gabapentin + Mecobalamin safe for children?
The safety and effectiveness of Gabapentin + Mecobalamin in children have not been fully established. Therefore, it should be given to children only under the supervision of a doctor.
Does Gabapentin + Mecobalamin interact with other medicines?
Yes, this combination may interact with antacids containing aluminium or magnesium, opioids (like morphine, methadone), CNS depressants (including alprazolam, zolpidem), and other anti-convulsants (such as phenytoin, carbamazepine).
Can Gabapentin + Mecobalamin cause mood changes?
In rare cases, Gabapentin + Mecobalamin may cause changes in mood or behaviour, including thoughts of suicide. If you notice any unusual changes in mood or behaviour, seek immediate medical attention.
Can I drive after taking Gabapentin + Mecobalamin?
Gabapentin + Mecobalamin may cause drowsiness, dizziness or trouble with coordination. These side effects could affect your ability to drive or operate machinery. Therefore, avoid driving or operating heavy machinery until you know how the medication affects you.
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