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Fluoxetine + Olanzapine

Uses of Fluoxetine + Olanzapine

  • Fluoxetine + Olanzapine is primarily used to manage depressive episodes related to bipolar I disorder, and belongs to a group of medicines known as selective serotonin reuptake inhibitor (SSRI) antidepressants and atypical antipsychotics.

Side effects of Fluoxetine + Olanzapine

  • Increased Appetite

  • Weight Gain

  • Dry Mouth

  • Fatigue

  • Dizziness

How Fluoxetine + Olanzapine works

  • Fluoxetine is a selective serotonin reuptake inhibitor (SSRI). This means it works by increasing the activity of a neurotransmitter called serotonin in the brain. Serotonin helps regulate mood, so having more of it available can help reduce symptoms of depression.

  • Olanzapine is an atypical antipsychotic. It acts by blocking certain receptors in the brain for chemicals like dopamine and serotonin. This helps to stabilize mood and reduce symptoms of mania in bipolar disorder. Together, these medicines work in synergy to relieve depressive symptoms in bipolar disorder while maintaining mood stability.

Certified content

Written By

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Dr Vatsalya D GhanekarMedical Content Writer| 5 Years

MD Ayurveda

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Fluoxetine + Olanzapine can be taken orally (capsule).

Age and Dose Restrictions

  • Fluoxetine + Olanzapine is specifically indicated for adults over the age of 18 years.

Contraindications

  • Fluoxetine + Olanzapine is contraindicated in patients with known hypersensitivity to fluoxetine, olanzapine, or any component of the formulation. It is also contraindicated in patients who have recently discontinued (within the last 14 days) monoamine oxidase inhibitors (MAOIs).

Other Medications to Avoid

  • Fluoxetine + Olanzapine can interact with monoamine oxidase inhibitors (such as phenelzine and selegiline), serotonergic medicines (e.g., triptans like sumatriptan), tricyclic antidepressants (such as amitriptyline), antiarrhythmics (like amiodarone), and medicines that prolong the QT interval (such as certain antipsychotics and antibiotics).

Overdose and Missed Dose

  • An overdose of this medication can cause severe symptoms such as hallucinations, fast heartbeat, muscle rigidity, high fever, and confusion. In case of suspected overdose, seek immediate medical attention.

  • If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage side effects like dry mouth and constipation.

  • Resting and avoiding sudden movements can help manage dizziness.

  • Regular eye check-ups are advised if blurred vision persists.

Use in Driving and Operating Machinery

  • Fluoxetine + Olanzapine may cause drowsiness and affect your ability to drive or operate machinery. Avoid these activities if you feel dizzy or sleepy after taking this medication.

Use in Pregnancy and Lactation

  • Fluoxetine + Olanzapine should only be used during pregnancy or while breastfeeding if the potential benefits justify the potential risks to the baby. Consult your doctor before using this medicine during these periods.

Caution in Other Conditions

  • Patients with diabetes should exercise caution when taking Fluoxetine + Olanzapine as it can affect blood sugar control.

  • Caution is also needed in patients with a history of seizures, glaucoma, or abnormal heart rhythms.

Special Dietary and Lifestyle Recommendations

  • Regular monitoring of blood sugar levels is advised for patients with diabetes.

  • Regular monitoring of blood pressure is recommended as this medication may cause a drop in blood pressure upon standing.

  • Regular eye check-ups are advised for those at risk of glaucoma.

Frequently asked questions

Yes, one of the common side effects of Fluoxetine + Olanzapine is weight gain. Increasing appetite may also lead to weight gain. It is advisable to monitor your weight regularly while taking this medicine and consult your doctor if you notice any significant weight changes.

Fluoxetine + Olanzapine might decrease sexual desire or ability in some people. If you notice any changes in your sexual drive or performance while taking this medicine, it is recommended to discuss this with your doctor.

It is not recommended to abruptly stop taking Fluoxetine + Olanzapine as it may cause withdrawal symptoms. You should always consult your doctor before stopping or adjusting the dose of any medication.

Yes, generic versions of Fluoxetine + Olanzapine are available. However, always consult with your doctor or pharmacist before switching from a branded medicine to its generic equivalent.

Yes, taking Fluoxetine + Olanzapine can cause an increase in appetite, which may lead to weight gain. If this becomes a concern, please discuss it with your doctor.

Yes, Fluoxetine + Olanzapine is prescribed to manage mood swings associated with bipolar I disorder. It can help stabilize mood and manage symptoms of both depression and mania.

There is no significant evidence suggesting that Fluoxetine + Olanzapine negatively impacts fertility. However, if you have concerns about fertility, it is best to consult your doctor for advice.

Terms & Conditions


Fluoxetine + Olanzapine in other salts

Available medicines for FLUOXETINE + OLANZAPINE
Olanex F 5/20 MG Tablet 10
Olanex F 5/20 MG Tablet 10
Emcure Pharmaceuticals Ltd
Pack of 10 Units
₹88.31
MRP ₹107.70
18.00% OFF
Flujoy 5/20 MG Tablet 10
Flujoy 5/20 MG Tablet 10
Mayflower India
Pack of 10 Units
₹49.20
MRP ₹60.00
18.00% OFF
Elanza Plus Tablet 10
Elanza Plus Tablet 10
Solvate Laboratories Pvt Ltd
Pack of 10 Units
₹73.80
MRP ₹90.00
18.00% OFF
Olaset F 20/5 MG Tablet 10
Olaset F 20/5 MG Tablet 10
Ardent Life Sciences Pvt Ltd
Pack of 10 Units
₹69.70
MRP ₹85.00
18.00% OFF
Depten Oz 5/20 MG Tablet 10
Depten Oz 5/20 MG Tablet 10
Psycormedies
Pack of 10 Units
₹49.20
MRP ₹60.00
18.00% OFF
Olanzia Plus Tablet 10
Olanzia Plus Tablet 10
Chemo Health Care Pvt Ltd
Pack of 10 Units
₹72.98
MRP ₹89.00
18.00% OFF

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