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Etomidate

Uses of Etomidate

  • The primary use of Etomidate is in the induction and maintenance of general anaesthesia for surgeries. This medicine belongs to the group of general anaesthetics.

  • It also has secondary uses in critical care settings, where it's used for sedating mechanically ventilated patients.

Side effects of Etomidate

  • Pain or reaction at the injection site

  • Nausea and vomiting

  • Respiratory depression (slow and shallow breathing)

  • Hypotension (low blood pressure)

  • Myoclonus (involuntary muscle jerking)

How Etomidate works

  • Etomidate is a short-acting intravenous anesthetic used for the induction of general anesthesia and sedation during short medical procedures.

  • It works by enhancing the effects of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the central nervous system, leading to sedation and unconsciousness. Etomidate is known for its rapid onset of action and minimal effects on cardiovascular function, making it useful in patients with unstable hemodynamics.

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Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Etomidate is available in a liquid form as a clear, colourless solution.

  • It is administered intravenously, meaning it is injected directly into a vein.

Age and Dose Restrictions

  • This medicine is meant for use in adults. The safety and efficacy of Etomidate in children have not been well established.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to Etomidate or any of its components.

  • It should be used with caution in patients who have a history of epilepsy or seizures.

Other Medications to Avoid

  • This medicine can interact with central nervous system depressants such as opioids (like morphine and fentanyl), benzodiazepines (such as diazepam and lorazepam), and barbiturates (like phenobarbital).

Overdose and Missed Dose

  • Symptoms of Etomidate overdose include profound respiratory depression, cardiovascular collapse, and coma. Treatment focuses on ventilatory and hemodynamic support.

  • If you miss a dose of Etomidate during a scheduled medical procedure, the administering medical team will adjust the timing and dosage as needed. It is used under strict medical supervision, so missed doses are typically managed by healthcare professionals in a clinical setting.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

  • For mild nausea or vomiting, adjusting the timing of the medication might help.

  • Staying hydrated may help alleviate mild headache or dizziness.

Use in Driving and Operating Machinery

  • Etomidate affects your ability to drive or operate machinery significantly as it induces sedation and impaired cognitive functions. Avoid these activities until full recovery from its effects.

Use in Pregnancy and Lactation

  • Etomidate should be used during pregnancy only if the potential benefits justify the potential risk to the foetus. It is not known if Etomidate is excreted in human milk. Consult your doctor before using this medicine during pregnancy or while breastfeeding.

Caution in Other Conditions

  • Patients with hepatic impairment should exercise caution when taking Etomidate as it undergoes metabolism primarily in the liver.

  • Although renal impairment does not significantly affect the pharmacokinetics of Etomidate, critically ill patients with renal failure may be more susceptible to its effects.

Special Dietary and Lifestyle Recommendations

To support general health during recovery from surgery or intensive care where Etomidate might be used:

  • Maintain a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to promote healing.

  • Adequate hydration is crucial; aim to drink six to eight glasses of water daily unless otherwise directed by a doctor due to specific health conditions.

  • Limit caffeine intake as it may exacerbate anxiety or sleep issues post-surgery.

  • Avoid alcohol as it can interfere with medications and delay recovery processes.

  • Prioritize rest and follow medical advice on gradually increasing activity levels to regain strength.

Frequently asked questions

No, Etomidate is not a steroid. It is an anaesthetic medication used to induce general anaesthesia prior to surgical procedures or for sedating mechanically ventilated patients.

Yes, Etomidate is a sedative medication that induces sleepiness or drowsiness. It is used to put patients to sleep before surgery.

There is no known evidence or scientific research that suggests Etomidate affects fertility. However, if you have concerns about this, it would be best to consult your doctor.

There are no known dietary restrictions while taking Etomidate. However, this medicine is typically administered in a hospital setting under the supervision of a healthcare professional.

Etomidate is generally not intended for daily use. It is typically used as a one-time injection before surgery or other medical procedures.

Etomidate acts quickly and its effects are generally felt within a minute after administration.

Etomidate is administered by a healthcare professional in a hospital setting, so patients do not need to worry about timing their doses.

Terms & Conditions

Available medicines for ETOMIDATE
Paranir 650 MG Tablet 10
Paranir 650 MG Tablet 10
Nirlife Healthcare
Pack of 10 Units
₹4.65
MRP ₹5.67
18.00% OFF
Celodate 20 MG Injection 1
Celodate 20 MG Injection 1
Celon Labs
Pack of 1 Units
₹426.40
MRP ₹520.00
18.00% OFF
Hypnodate 2 MG Injection 10 ML
Hypnodate 2 MG Injection 10 ML
Neon Laboratories Ltd
Pack of 10 ML
₹446.08
MRP ₹544.00
18.00% OFF
Troymidate Injection 10 ML
Troymidate Injection 10 ML
Troikaa Pharmaceuticals Ltd
Pack of 10 ML
₹383.35
MRP ₹467.50
18.00% OFF

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