Home/Drugs By Ailments / Dactinomycin

Dactinomycin

Uses of Dactinomycin

  • Dactinomycin, an antitumor antibiotic, is chiefly used to manage several types of cancer including Wilms' tumour, rhabdomyosarcoma, Ewing's sarcoma, gestational trophoblastic neoplasia, and testicular cancer that has spread to other parts of the body.

Side effects of Dactinomycin

  • Nausea and vomiting

  • Loss of appetite

  • Diarrhoea or constipation

  • Mouth sores or ulcers

  • Fatigue and weakness

  • Hair loss

  • Skin rash or itching

How Dactinomycin works

  • Dactinomycin is a chemotherapy medicine used to treat various types of cancer, including certain sarcomas and testicular cancer.

  • It works by binding to DNA and inhibiting RNA synthesis, which prevents cancer cells from growing and dividing. Dactinomycin is typically used in combination with other treatments to enhance its effectiveness.

Certified content

Written By

docImg
Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 Years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Dactinomycin is available for use as an injectable medication through the intravenous route.

Age and Dose Restrictions

  • This medicine is meant for use in both adults and children. Specific age restrictions depend on the type and stage of cancer being managed.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to Dactinomycin. It is also contraindicated in patients with severe bone marrow suppression, severe liver disease, or severe kidney disease.

Other Medications to Avoid

  • This medicine can interact with antineoplastic agents (such as cisplatin, doxorubicin, and etoposide), radiation therapy, immunosuppressants (like cyclosporine and tacrolimus), hepatotoxic medications (such as acetaminophen, ketoconazole, and rifampin), and antibiotics (like aminoglycosides).

Overdose and Missed Dose

  • An overdose of Dactinomycin may result in severe adverse effects like damage to internal organs. Immediate medical attention should be sought if an overdose is suspected.

  • If a dose of Dactinomycin is missed, the next dose should be administered as scheduled. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For side effects such as nausea or loss of appetite, try taking the medication at different times or after meals.

  • Staying hydrated may help manage mild side effects like fatigue or weakness.

Use in Driving and Operating Machinery

  • This medicine does not generally affect the ability to drive or operate machinery. However, individual responses can vary, and it is essential to know how you respond to Dactinomycin before engaging in such activities.

Use in Pregnancy and Lactation

  • Dactinomycin is not recommended for use during pregnancy or while breastfeeding. The potential risks to the fetus or infant must be weighed against the benefits of using this medicine in cancer management. Always consult your doctor for advice on using this medication during pregnancy and lactation.

Caution in Other Conditions

  • Patients with existing liver or kidney conditions should use Dactinomycin with caution.

  • Regular monitoring of liver and kidney function may be necessary while using this medicine.

Special Dietary and Lifestyle Recommendations

  • Maintain adequate hydration to support body functions during cancer treatment.

  • A balanced diet rich in vitamins and minerals can help maintain body strength and enhance recovery.

  • Avoid excessive sun exposure as Dactinomycin can increase skin sensitivity; wearing protective clothing and using sunscreen when outdoors is advisable.

  • Since immunity may be compromised during treatment with Dactinomycin, maintaining cleanliness and avoiding contact with sick individuals can prevent infections.

Frequently asked questions

Yes, hair loss (alopecia) is one of the common side effects of Dactinomycin. However, it often grows back after treatment is completed.

Dactinomycin can decrease your body's white blood cell count, making you more prone to infections. Thus, it is advisable to avoid close contact with people who have infections while taking this medication.

Yes, Dactinomycin may increase your skin's sensitivity to sunlight. It is recommended that you protect your skin from excessive sun exposure while on this medication.

While taking Dactinomycin, it is advisable to avoid vaccinations, particularly live vaccines, without consulting your doctor.

There is no specific information about the interaction between alcohol and Dactinomycin. However, considering the medicine's effects on liver function, it would be best to consult your doctor about this.

Dactinomycin should be stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F), and protected from light. It should be prepared and administered only by healthcare professionals trained in handling chemotherapeutic agents.

No, dactinomycin is not a steroid.

Terms & Conditions

Available medicines for DACTINOMYCIN
Cosmegen 500 MCG Injection 1 ML
Cosmegen 500 MCG Injection 1 ML
Wockhardt Ltd
Pack of 1 ML
₹74.28
MRP ₹90.58
18.00% OFF
Dacilon 0.5 MG Injection 1
Dacilon 0.5 MG Injection 1
Celon Labs
Pack of 1 Units
₹364.90
MRP ₹445.00
18.00% OFF
Dacmozen 0.5 MG Injection 2 ML
Dacmozen 0.5 MG Injection 2 ML
Vhb Life Sciences Limited
Pack of 2 ML
₹573.18
MRP ₹699.00
18.00% OFF
Actinocin 0.5 MG Injection 1
Actinocin 0.5 MG Injection 1
Neon Laboratories Ltd
Pack of 1 Units
₹405.90
MRP ₹495.00
18.00% OFF

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.

playstoreIcon

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v3.3.6

copyright2024 - Truemeds | All rights reserved

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner