Colchicine
Uses of Colchicine
The primary use of Colchicine is to manage and prevent gout attacks. It is part of a category of medicines known as anti-gout agents.
Besides being used for gout, Colchicine also aids in managing familial Mediterranean fever (FMF) in both adults and children aged four years or older.
Side effects of Colchicine
Diarrhoea
Nausea
Vomiting
Abdominal Pain
How Colchicine works
Colchicine is an anti-gout medication or agent.
It functions by reducing inflammation in the body. This is achieved by inhibiting the migration of a specific type of white blood cells, called granulocytes, to areas of inflammation. By doing so, it reduces the build-up of uric acid crystals that trigger pain and swelling in joints affected by gout. This helps to manage the symptoms of gout attacks and familial Mediterranean fever (FMF).
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Colchicine is available as an oral tablet intended for ingestion. It is to be swallowed and can be taken with or without food as per the doctor's advice.
Age and Dose Restrictions
This medicine is appropriate for use in adults and children 4 years or older.
Contraindications
Colchicine is contraindicated for patients who have severe kidney or liver disease.
Patients who are on strong inhibitors of CYP3A4 or P-glycoprotein, and have liver or kidney impairment should also avoid this medication.
Other Medications to Avoid
Colchicine can interact with antibiotics (such as clarithromycin, erythromycin and telithromycin), antifungals (itraconazole and ketoconazole), HIV medications (atazanavir, indinavir, nelfinavir, ritonavir and saquinavir) and heart medications (diltiazem, verapamil and quinidine).
Overdose and Missed Dose
An overdose of Colchicine can lead to severe symptoms like nausea, vomiting, diarrhoea, abdominal pain, muscle weakness, and organ failure. It is essential to seek immediate medical attention if an overdose is suspected.
If you forget to take your dose of Colchicine, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose. Do not take two doses at once.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids can help manage some of the gastrointestinal side effects such as diarrhoea and nausea.
Resting and avoiding heavy physical activity can lessen muscle pain or weakness.
Use in Driving and Operating Machinery
Colchicine may cause dizziness or fatigue in some patients. It is advised to avoid driving or operating heavy machinery if you experience these side effects.
Use in Pregnancy and Lactation
Colchicine is not recommended for use in pregnant women unless the benefits outweigh the risks.
This medicine may pass into breast milk. Nursing mothers should consult their doctor before using Colchicine.
Caution in Other Conditions
Patients with kidney or liver disease need to exercise caution when taking Colchicine. Dosage adjustment may be necessary based on the degree of impairment.
Individuals with a history of stomach disorders should also take this medication with caution.
Special Dietary and Lifestyle Recommendations
Maintain a healthy weight: Being overweight can increase the risk of gout.
Be physically active: Regular physical activity can help maintain a healthy weight and reduce the risk of gout attacks.
Avoid foods high in purines: Foods high in purines, such as red meat and seafood, can increase uric acid levels in the body. Try to limit these foods to prevent gout attacks.
Frequently asked questions
Does Colchicine require a prescription, or is it available over the counter?
Colchicine typically requires a prescription and is not usually available over the counter. It is important to consult your doctor for accurate dosage and administration instructions based on your specific health condition.
Is Colchicine a steroid?
No, Colchicine is not a steroid. It belongs to a class of medicines known as anti-gout agents.
Does Colchicine have any effect on sleep?
Colchicine is not associated with affecting sleep patterns. However, if you notice any changes in your sleep patterns while taking this medication, please inform your doctor.
How much time does it take for Colchicine to start working?
The time taken for Colchicine to start showing its effects can vary from person to person and also depends on the condition being managed. Consult your doctor for more information relevant to your specific health condition.
Are there natural alternatives to Colchicine?
There are no known direct natural alternatives to Colchicine. However, lifestyle changes such as a balanced diet, regular exercise and maintaining a healthy weight can aid in managing symptoms of conditions like gout.
Can the intake of Colchicine lead to weight gain?
Weight gain is not a reported side effect of taking Colchicine. However, every individual may respond differently to medicines and experience different side effects. If you notice unexplained weight gain while taking Colchicine, consult your doctor.
Does Colchicine affect mood or cause mood swings?
Colchicine is not directly associated with affecting mood or causing mood swings. However, any medicine can have different effects on different individuals. If you notice any significant changes in your mood or behaviour while taking Colchicine, consult your doctor immediately.
Subscribe
Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.
Download Truemeds
Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Contact Us
Our customer representative team is available 7 days a week from 9 am - 9 pm.
v3.3.6
2024 - Truemeds | All rights reservedOur Payment Partners
