Clomipramine

Expert Advice

Dosage Forms Available

• Clomipramine can be taken orally (tablets, capsules, or an oral solution).

Age and Dose Restrictions

• Clomipramine is intended for use in adults and children aged 10 years and above.

Contraindications

• Clomipramine is contraindicated in individuals with a known hypersensitivity to Clomipramine or any tricyclic antidepressants.

• It should not be used by individuals who have recently had a heart attack or have severe liver impairment.

Other Medications to Avoid

• Clomipramine can interact with Monoamine Oxidase Inhibitors (such as Isocarboxazid and phenelzine), Selective Serotonin Reuptake Inhibitors (SSRIs), serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) (like Fluoxetine and venlafaxine), triptans (Sumatriptan and rizatriptan), and Opiate analgesics (Tramadol).

• It can also interact with antiarrhythmics (Quinidine, Flecainide), anticholinergics (Benztropine, Dicyclomine), barbiturates (Phenobarbital), anticonvulsants (Phenytoin and Carbamazepine) and anticoagulants (Warfarin).

Overdose and Missed Dose

• Overdose of Clomipramine may cause irregular heartbeat, hypotension, seizures, coma, or respiratory depression. If this occurs, immediately contact poison control or emergency medical services.

• If you missed a dose of Clomipramine, take the medication as soon as you remember. However, avoid doubling the dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage dry mouth, try chewing sugar-free gum or sucking on sugar-free sweets.

• If you're experiencing constipation, try to add more fibre to your diet and drink plenty of water.

• Drowsiness can be managed by taking the medication at bedtime.

Use in Driving and Operating Machinery

• Clomipramine may cause drowsiness and dizziness. Therefore, it is advised not to drive or operate machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

• It is recommended to consult with your doctor before using Clomipramine during pregnancy and breastfeeding.

Caution in Other Conditions

• Caution should be exercised when using Clomipramine in individuals with conditions such as seizures, glaucoma, heart disease, liver or kidney disease, bipolar disorder, and schizophrenia.

Special Dietary and Lifestyle Recommendations

• Regular exercise may help reduce anxiety and improve mood.

• A balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats can support overall mental health.

• Try to limit caffeine intake as it may exacerbate feelings of anxiety.

• Practising mindfulness techniques such as meditation or yoga can help manage stress levels.

Frequently asked questions

Terms & Conditions