Chlorpheniramine Maleate + Diethylcarbamazine
Uses of Chlorpheniramine Maleate + Diethylcarbamazine
Chlorpheniramine Maleate + Diethylcarbamazine is primarily used for managing filariasis, a parasitic infection caused by roundworms. This combination belongs to the group of antiparasitic and antihistamine medicines.
Besides, it effectively helps in relieving symptoms associated with these worm infections, such as itching, swelling, hives, and redness.
Side effects of Chlorpheniramine Maleate + Diethylcarbamazine
Drowsiness or dizziness
Dry mouth, nose, or throat
Nausea or vomiting
Blurred vision
Restlessness or excitability
How Chlorpheniramine Maleate + Diethylcarbamazine works
Chlorpheniramine Maleate is an antihistamine. It competes with histamine for H1-receptor sites on effector cells in the body. By blocking the effects of histamine released during allergic reactions, it helps alleviate symptoms such as itching, swelling, rashes, and hives that may occur as the worms die off.
Diethylcarbamazine is an anthelmintic. It works by disrupting the metabolism and reproduction of susceptible worms. It paralyses the young worms, also known as microfilariae, and alters the adult worms' surface membrane, rendering them more vulnerable to destruction by the body's immune system. This leads to the death of these parasitic worms. Together, these two components work in unison to effectively rid the body of parasitic worm infections while also managing the associated allergic symptoms.
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Written By
Bachelor of Dental Surgery
Reviewed By
Doctor of Medicine
Expert Advice
Dosage Forms Available
Chlorpheniramine Maleate + Diethylcarbamazine is available in the form of oral tablets and syrups.
Age and Dose Restrictions
This medication is suitable for use in adults and children above 6 years of age.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to either diethylcarbamazine or chlorpheniramine.
Other Medications to Avoid
This combination may interact with opioids (such as morphine), sedatives (like diazepam), muscle relaxants (including flexeril), MAO inhibitors (such as isocarboxazid), and tricyclic antidepressants (like amitriptyline).
Overdose and Missed Dose
An overdose can cause severe drowsiness, convulsions, and decreased heart rate. If you suspect an overdose, seek medical help immediately.
If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next dose, skip the missed dose and go back to your regular schedule. Do not double up on doses.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids can help manage dry mouth, nose, or throat.
Taking the medication with food can help manage nausea, vomiting, stomach pain or loss of appetite.
Use in Driving and Operating Machinery
This medication may cause drowsiness or dizziness. Therefore, caution should be taken when driving or operating heavy machinery until you know how this medication affects you.
Use in Pregnancy and Lactation
It should only be used if the potential benefits outweigh the risks. Consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution in Other Conditions
Patients with liver or kidney disease should exercise caution when taking Chlorpheniramine Maleate + Diethylcarbamazine.
Caution should also be exercised in patients with cardiovascular disease, as this medication may cause an irregular heartbeat or chest pain.
Special Dietary and Lifestyle Recommendations
Regularly monitoring your blood pressure and heart rate can help manage any cardiovascular effects of this medication.
Trying to keep a consistent sleep schedule can help manage side effects such as drowsiness and insomnia.
Frequently asked questions
Is Chlorpheniramine Maleate + Diethylcarbamazine a steroid?
No, Chlorpheniramine Maleate + Diethylcarbamazine is not a steroid. This combination consists of an antiparasitic agent (Diethylcarbamazine) and an antihistamine (Chlorpheniramine Maleate). Together, they work to kill parasitic worms and manage the allergic symptoms associated with these infections.
Does Chlorpheniramine Maleate + Diethylcarbamazine have any effect on menstruation?
No, Chlorpheniramine Maleate + Diethylcarbamazine is not known to affect menstruation. However, any unusual changes should be discussed with a doctor.
Is it safe to take Chlorpheniramine Maleate + Diethylcarbamazine daily?
Chlorpheniramine Maleate + Diethylcarbamazine should be taken as prescribed by your doctor. The duration and frequency of use will depend on the specific condition being managed and individual patient factors.
How much time does Chlorpheniramine Maleate + Diethylcarbamazine take to work?
The antiparasitic effects of Diethylcarbamazine may take a few days to weeks to become evident. On the other hand, the antihistamine action of Chlorpheniramine Maleate usually provides symptom relief within a few hours of taking the medication.
What is the best time to take Chlorpheniramine Maleate + Diethylcarbamazine?
This medication should be taken as directed by your doctor. As it can cause drowsiness, some people may choose to take it at night.
Will Chlorpheniramine Maleate + Diethylcarbamazine affect fertility?
Chlorpheniramine Maleate + Diethylcarbamazine is not associated with any effects on fertility. However, if you have concerns about fertility or are trying to conceive, it is best to discuss these concerns with your doctor.
Is there a vegetarian alternative to Chlorpheniramine Maleate + Diethylcarbamazine?
The composition of medicine tablets can vary and may contain non-vegetarian ingredients. You should consult your doctor or pharmacist to find out if a vegetarian alternative is available.
Chlorpheniramine Maleate + Diethylcarbamazine in other salts
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