Cefpirome
Uses of Cefpirome
Cefpirome is primarily used for managing a range of bacterial infections, including urinary tract infections, skin and soft tissue infections, bloodstream infections, intra-abdominal infections, genital infections and respiratory tract infections. It belongs to the group of fourth-generation cephalosporin antibiotics.
Side effects of Cefpirome
Diarrhea
Nausea
Vomiting
Headache
Rash
How Cefpirome works
Cefpirome is a fourth-generation cephalosporin antibiotic.
It acts by inhibiting the production of bacterial cell walls. It achieves this by binding to and disabling penicillin-binding proteins, which are key enzymes required to build a major part of the bacterial cell wall known as peptidoglycan. This disruption in the formation of the cell wall leads to the bursting and subsequent death of the bacterial cells. Additionally, Cefpirome is effective against many bacteria that produce beta-lactamases, enzymes that often make bacteria resistant to other antibiotics. This enhances its ability to manage a broader range of bacterial infections.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Cefpirome can be administered via the intravenous route (injection).
Age and Dose Restrictions
Cefpirome is meant for adults and children over 12 years of age.
Contraindications
This medicine is contraindicated in patients with a known allergy to Cefpirome or any other cephalosporin antibiotics. It should also not be used by patients with severe renal impairment.
Other Medications to Avoid
Cefpirome may interact with aminoglycosides (such as gentamicin and neomycin), diuretics (like furosemide), and anticoagulants (such as warfarin).
Overdose and Missed Dose
Overdose of Cefpirome can lead to symptoms like seizure, severe nausea, vomiting, and diarrhoea. If you suspect an overdose, seek immediate medical attention.
If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take double doses to make up for the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage some gastrointestinal side effects like nausea and diarrhoea.
Resting and avoiding intense physical activity can help manage dizziness or fatigue.
Use in Driving and Operating Machinery
Cefpirome may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating heavy machinery until you are sure you can perform these activities safely.
Use in Pregnancy and Lactation
It is recommended to consult your doctor before using Cefpirome during pregnancy and lactation. The potential benefits must be weighed against the potential risks before taking this medicine.
Caution in Other Conditions
Patients with kidney problems or a history of penicillin allergy should exercise caution when using Cefpirome. Regular kidney function tests may be required to monitor the effect of this medicine on the kidneys.
Special Dietary and Lifestyle Recommendations
Adequate hydration is essential for overall health and can help manage some side effects associated with Cefpirome.
Frequently asked questions
Can Cefpirome cause mood changes?
While not common, some people may experience mood changes when taking Cefpirome. If you experience any unusual mood swings or changes in behaviour, contact your doctor immediately.
Is there a natural alternative to Cefpirome?
There is no natural alternative that has been proven to be as effective as Cefpirome for managing bacterial infections. Antibiotics are prescribed by doctors based on the type of infection and the patient's medical history.
Is there a vegan option for Cefpirome?
Cefpirome does not contain any animal-derived ingredients. However, if you are concerned about the excipients or additives in the medication, you should discuss this with your doctor or pharmacist.
Can Cefpirome cause weight gain?
There is no evidence to suggest that Cefpirome causes weight gain. However, individual responses to medicine can vary.
Does Cefpirome have any effect on menstruation?
No known effect of Cefpirome has been reported on menstruation. However, if you notice any irregularities or changes, please consult your doctor.
How quickly does Cefpirome begin to work?
Cefpirome begins to work soon after it is administered, but the time may vary depending on the type and severity of the infection.
Is Cefpirome safe for long-term use?
Cefpirome should be used as recommended by your doctor. Long-term use without medical advice may lead to antibiotic resistance.
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