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Bupropion

Uses of Bupropion

  • Bupropion is primarily used to manage Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). It also aids in smoking cessation. It belongs to the class of atypical antidepressants.

  • While Bupropion is not typically the first choice for treating depression, it can be an effective option for individuals who have not responded well to other antidepressants.

Side effects of Bupropion

  • Dry mouth

  • Nausea

  • Insomnia

  • Headache

  • Dizziness

How Bupropion works

  • Bupropion is an atypical antidepressant.

  • It works by inhibiting, that is, blocking the reuptake of two neurotransmitters, namely dopamine and norepinephrine, in the brain. Neurotransmitters are chemicals that transmit signals between nerve cells. By blocking their reuptake, Bupropion increases their levels in the brain. This helps in regulating mood, reducing depression and enhancing general well-being. The exact way in which Bupropion helps with smoking cessation is not fully understood. However, it is believed to influence the reward pathways in the brain. This results in a reduction in cravings for and withdrawal symptoms of nicotine, assisting individuals to quit smoking.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 Years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer|

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Bupropion can be taken orally (immediate-release (IR) tablets, sustained-release (SR) tablets and extended-release (XL) tablets).

Age and Dose Restrictions

  • Bupropion is primarily intended for adults.

Contraindications

  • Bupropion is contraindicated in patients with a history of seizures or eating disorders such as anorexia or bulimia because of the increased risk of seizures associated with its use. It is also contraindicated in individuals who are currently abstaining from alcohol, benzodiazepines, barbiturates, or antiepileptic medicines due to the risk of withdrawal seizures. Lastly, individuals with known hypersensitivity or allergy to Bupropion should avoid its use.

Other Medications to Avoid

  • Bupropion may interact with monoamine oxidase inhibitors (MAOIs such as selegiline or phenelzine), antipsychotics (like quetiapine or risperidone), bronchodilators (like theophylline, doxofylline), and systemic corticosteroids (such as prednisolone or dexamethasone).

Overdose and Missed Dose

  • In case of an overdose of Bupropion, immediate medical attention should be sought. Overdose symptoms can include hallucinations, loss of consciousness, heart palpitations, and seizures.

  • If you miss a dose of Bupropion, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your usual dosing schedule. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects of Bupropion are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.

  • Drinking plenty of water can help manage side effects such as dry mouth and constipation.

  • If you experience insomnia, try taking your last dose of the day earlier to avoid interference with sleep.

Use in Driving and Operating Machinery

  • Bupropion may cause dizziness, confusion or impaired judgement. Therefore, caution should be exercised when driving or operating heavy machinery while taking Bupropion.

Use in Pregnancy and Lactation

  • It is advised to consult a doctor before using Bupropion during pregnancy or breastfeeding. The benefits of Bupropion must be weighed against potential risks to the foetus or baby.

Caution in Other Conditions

  • Patients with liver or kidney impairment may need adjusted doses of Bupropion. Similarly, elderly patients and those with a history of head trauma or seizures should exercise caution when taking Bupropion due to an increased risk of seizures.

Special Dietary and Lifestyle Recommendations

  • Practice relaxation techniques like yoga, meditation, or deep breathing exercises to help manage stress and anxiety, which can exacerbate depression or increase nicotine cravings.

Frequently asked questions

No, Bupropion is not a steroid. It is an antidepressant medication that falls into the category of atypical antidepressants. It is primarily used to manage major depressive disorder, and seasonal affective disorder, and help in smoking cessation.

Bupropion is not directly associated with affecting fertility. If you have concerns about fertility related to taking Bupropion, you should consult with your doctor.

Yes, it is generally considered safe to take Bupropion daily when it is prescribed by your doctor.

You may begin to notice the effects of Bupropion in 1-2 weeks for smoking cessation and 4-6 weeks for depression and seasonal affective disorder. However, everyone's response may vary.

The best time to take Bupropion depends on the specific formulation you have been prescribed and your doctor's instructions.

The duration of treatment with Bupropion varies depending on what it is being used for and the individual's response to the medication. Always adhere to your doctor’s prescription.

Bupropion requires a prescription and is not available over the counter.

Terms & Conditions

Available medicines for BUPROPION
Buprex 150 MG Tablet Sr 10
Buprex 150 MG Tablet Sr 10
Bondane Pharma
Pack of 10 Units
₹73.80
MRP ₹90.00
18.00% OFF
Bupron Sr 300 MG Tablet 10
Bupron Sr 300 MG Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹67.24
MRP ₹82.00
18.00% OFF
Bupron 100 MG Tablet 10
Bupron 100 MG Tablet 10
Cipla Ltd.
Pack of 10 Units
₹67.24
MRP ₹82.00
18.00% OFF
Smoquit Sr 150 MG Tablet 10
Smoquit Sr 150 MG Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹124.64
MRP ₹152.00
18.00% OFF
Zupion Sr 150 MG Tablet 10
Zupion Sr 150 MG Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹86.92
MRP ₹106.00
18.00% OFF
Zyban 150 MG Tablet 10
Zyban 150 MG Tablet 10
Glaxosmithkline Pharmaceuticals Ltd.
Pack of 10 Units
₹328.00
MRP ₹400.00
18.00% OFF
Atydep Sr 150 MG Tablet 10
Atydep Sr 150 MG Tablet 10
Ikon Remedies Pvt Ltd
Pack of 10 Units
₹63.96
MRP ₹78.00
18.00% OFF
Zyban Sr 150 MG Tablet 10
Zyban Sr 150 MG Tablet 10
Glaxosmithkline Pharmaceuticals Ltd.
Pack of 10 Units
₹328.00
MRP ₹400.00
18.00% OFF

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