Benzathine Penicillin G
Uses of Benzathine Penicillin G
The primary use of Benzathine Penicillin G is to manage certain bacterial infections including syphilis, yaws, bejel, and pinta. It belongs to the group of penicillin antibiotics.
This medicine is also indicated for the management of rheumatic fever, prevention of recurrent rheumatic fever and rheumatic heart disease, and mild to moderate upper respiratory tract infections. Additionally, it is used as a prophylaxis against bacterial endocarditis in dental procedures for high-risk patients.
Side effects of Benzathine Penicillin G
Injection site pain, swelling, or redness
Low-grade fever
Nausea and vomiting
Headache
Fatigue
How Benzathine Penicillin G works
Benzathine Penicillin G is an antibiotic. It works by stopping the growth of bacteria. Specifically, it attaches to and inactivates specific enzymes, known as penicillin-binding proteins, that are essential for the synthesis of bacterial cell walls. Without a fully functional cell wall, the bacterial cells cannot survive, leading to their destruction.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Benzathine Penicillin G is available for use via the intramuscular route in the form of a suspension for injection.
Age and Dose Restrictions
This medicine is meant for both adults and children of age above 12 years.
Contraindications
Benzathine Penicillin G is contraindicated in patients with a history of severe allergic reactions to any penicillin antibiotic.
It is also contraindicated in patients with a history of anaphylaxis to any allergen.
Other Medications to Avoid
This medicine can interact with antigout agents (such as probenecid), antimetabolites (such as methotrexate), and aminoglycosides (like gentamicin and neomycin).
Overdose and Missed Dose
An overdose of this medicine may cause severe reactions including seizures, particularly in patients with renal impairment. If you observe any abnormal symptoms, inform your doctor immediately.
If you forget to administer this medicine, ensure it is administered as soon as you remember. Never repeat the dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids can help manage side effects such as nausea and diarrhoea.
Rest techniques can help manage the feelings of fatigue.
Cool compresses or a gentle massage can help manage the pain, swelling or redness at the injection site.
Use in Driving and Operating Machinery
This medication may affect your ability to drive or operate heavy machinery due to side effects such as dizziness. Avoid such activities if these symptoms occur.
Use in Pregnancy and Lactation
It is advisable to consult your doctor before using this medicine during pregnancy and breastfeeding.
Caution in Other Conditions
Benzathine Penicillin G should be used with caution in patients with a history of allergies, especially to penicillins or cephalosporins.
Patients with kidney dysfunction may require a reduced dosage of this medicine.
Special Dietary and Lifestyle Recommendations
Maintain good personal hygiene to prevent recurrent infections.
Regular check-ups with your doctor can help monitor the progress and effectiveness of the medication.
If you have been diagnosed with a sexually transmitted disease, ensure you follow safe sex practices to avoid spreading it to others.
Frequently asked questions
Does Benzathine Penicillin G cause drowsiness?
Benzathine Penicillin G is not associated with influencing drowsiness. However, individual reactions can vary, and if you experience any unusual symptoms, you should consult your doctor.
Can Benzathine Penicillin G cause weight gain?
Benzathine Penicillin G is not directly associated with affecting weight gain. If you notice any significant weight changes, it is advisable to consult your doctor.
Does Benzathine Penicillin G affect menstrual periods?
Benzathine Penicillin G is not associated with affecting menstrual periods. If you notice any changes in your menstrual pattern while on this medication, please consult your doctor.
Does Benzathine Penicillin G require a prescription?
Yes, Benzathine Penicillin G usually requires a prescription from a doctor and is not available over the counter.
Is Benzathine Penicillin G a steroid?
No, Benzathine Penicillin G is not a steroid. It is an antibiotic medicine used to manage certain bacterial infections.
How long does Benzathine Penicillin G stay in the body?
Benzathine Penicillin G stays in the body for an extended period after being injected into a muscle. A single intramuscular dose provides low but persistent serum levels of penicillin for up to 4 weeks.
Is Benzathine Penicillin G a vegetarian medicine?
Yes, Benzathine Penicillin G does not contain any animal-derived components. However, it is always best to check the product packaging or consult your doctor for more information.
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