Ampicillin + Dicloxacillin
Uses of Ampicillin + Dicloxacillin
Ampicillin + Dicloxacillin is mainly used for managing bacterial infections. It is a combination antibiotic medicine that contains two penicillin-type medicines.
It is indicated for the management of respiratory tract infections, urinary tract infections, gastrointestinal tract infections, meningitis, septicemia, endocarditis, bone and joint infections, and skin and soft tissue infections.
Side effects of Ampicillin + Dicloxacillin
Nausea
Diarrhoea
Skin rash
Headache
Dizziness
How Ampicillin + Dicloxacillin works
Ampicillin works by disabling the process that bacteria use to construct their cell walls. It binds to specific proteins in the bacteria, causing the cell wall to weaken and eventually rupture, leading to bacterial cell death.
Dicloxacillin complements this action. It, too, inhibits the formation of bacterial cell walls in a similar way, leading to the death of the bacteria.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Ampicillin + Dicloxacillin can be taken orally (oral suspension or capsule).
Age and Dose Restrictions
The use of Ampicillin + Dicloxacillin is recommended for adults and children.
Contradictions
Ampicillin + Dicloxacillin is contraindicated in patients with a known hypersensitivity to penicillins or cephalosporins.
It should not be used in patients with infectious mononucleosis.
Other Medications to Avoid
This combination may interact with uricosuric agents (such as probenecid), xanthine oxidase inhibitors (such as allopurinol), and aminoglycosides (such as gentamicin, and tobramycin).
Overdose and Missed Dose
An overdose of Ampicillin + Dicloxacillin may result in severe nausea, vomiting, diarrhoea, or abdominal pain. In such cases, contact your doctor immediately.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and resume your usual dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage nausea or upset stomach, it might be helpful to take this medicine with food.
If diarrhoea persists, drink plenty of fluids to stay hydrated.
Use in Driving and Operating Machinery
Ampicillin + Dicloxacillin may cause dizziness. Avoid driving and operating heavy machinery if you experience this side effect after taking the medicine.
Use in Pregnancy and Lactation
Ampicillin + Dicloxacillin is classified as pregnancy category B. However, it is always advised to consult your doctor before using this combination during pregnancy or breastfeeding.
Caution in Other Conditions
Patients with renal impairment or liver disease should exercise caution when taking Ampicillin + Dicloxacillin, as the medication is primarily eliminated by the kidneys.
Special Dietary and Lifestyle Recommendations
Consuming a balanced diet rich in fruits, vegetables, lean proteins, and whole grains can help strengthen your immune system and aid in quicker recovery from infections.
Adequate hydration is essential while taking antibiotics to help your body recover and prevent dehydration from potential side effects such as diarrhoea.
Regular rest and sleep are key to recovery from any infection. Ensure you get ample rest to allow your body to heal.
Frequently asked questions
Does Ampicillin + Dicloxacillin affect mood or emotions?
There is no scientific evidence to suggest that Ampicillin + Dicloxacillin directly affects mood or emotions. However, you should consult your doctor immediately.
Can I take Ampicillin + Dicloxacillin if I am vegan or vegetarian?
Yes, Ampicillin + Dicloxacillin can be taken by individuals following a vegan or vegetarian diet.
Does Ampicillin + Dicloxacillin cause dependency or withdrawal symptoms?
No, Ampicillin + Dicloxacillin does not cause dependency or withdrawal symptoms since it is an antibiotic and not a narcotic or psychoactive medicine.
Can Ampicillin + Dicloxacillin be used for off-label purposes?
While Ampicillin + Dicloxacillin has its approved uses, using it for anything other than these should be done on the expert advice of your doctor.
How long does it take for Ampicillin + Dicloxacillin to leave the body?
The half-life of Ampicillin is 1-1.5 hours, and that of Dicloxacillin is 0.7-1 hour. This means that within this time period, half the medicine is eliminated from the body.
Can Ampicillin + Dicloxacillin cause allergic reactions?
Yes, serious and occasionally fatal hypersensitivity reactions have been reported with the use of penicillins like Ampicillin + Dicloxacillin. If an allergic reaction occurs, the medicine should be discontinued immediately.
Can Ampicillin + Dicloxacillin be taken for viral infections?
No, Ampicillin + Dicloxacillin is an antibiotic medication that is effective against bacterial infections, not viral infections.
Ampicillin + Dicloxacillin in other salts
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